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Archive for the ‘genetics’ category: Page 353

Oct 28, 2019

How sunlight on the skin directly affects the gut microbiome

Posted by in categories: biotech/medical, genetics

New research from a team of Canadian scientists has for the first time demonstrated how exposure to Narrow Band Ultraviolet B light (UVB) can directly influence gut microbiome diversity in humans. The research hypothesizes that this result is modulated by vitamin D and presents evidence of a novel skin-gut communication pathway.

Autoimmune diseases such as inflammatory bowel disease (IBD) and multiple sclerosis are thought to be caused by a number of environmental and genetic factors. Gut bacterial diversity, exposure to sunlight and vitamin D levels, have all been observed as influential factors for inflammatory disease, however a new study is asserting a causal chain may link all three of these elements.

The new research examined 21 female subjects who were all administered three 60-second full-body UVB exposure sessions across one week. Blood and fecal samples were taken from all subjects at the beginning and end of the study to track changes to vitamin D levels and gut bacterial diversity. Half of the subjects were noted as having taken vitamin D supplements across the prior three winter months.

Oct 28, 2019

Genetic testing

Posted by in categories: economics, genetics

The low cost of genetic testing has prompted a slew of Chinese companies, including 23Mofang and Shenzhen-based WeGene, to enter the market and tap growing demand in the world’s second largest economy, which is expected to reach US$4.3 billion by 2023. Compared to the US, China remains a fairly nascent market for direct-to-consumer genetic testing.


The low cost of direct-to-consumer genetic testing has prompted a slew of Chinese companies to enter the domestic market, which is expected to reach US$4.3 billion by 2023.

Oct 27, 2019

Rare Diseases! — University of Pennsylvania’s Dr. David Fajgenbaum, MD — ideaXme — Ira Pastor

Posted by in categories: aging, bioengineering, biotech/medical, business, DNA, genetics, health, life extension, science, transhumanism

Oct 26, 2019

We May Not Have to Age So Fast

Posted by in categories: genetics, life extension

Researchers in epigenetics are learning how to slow down—and even turn back—the clock that governs aging in our cells.

Oct 25, 2019

Intensive DNA search yields 10 genes tied directly to schizophrenia

Posted by in categories: biotech/medical, genetics, neuroscience


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Rare genetic variants could point to new treatments for severe psychiatric disorder.

Oct 25, 2019

New gene editing tool is more powerful than CRISPR and could fix 89% of genetic defects

Posted by in categories: bioengineering, biotech/medical, genetics

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Oct 25, 2019

New gene editing technology could correct 89% of genetic defects

Posted by in categories: bioengineering, biotech/medical, genetics

Scientists have developed a new gene-editing technology that could potentially correct up to 89% of genetic defects, including those that cause diseases like sickle cell anemia.

The new technique is called “prime editing,” and was developed by researchers from the Broad Institute of MIT and Harvard, who published their findings Monday in the journal Nature.

Prime editing builds on powerful CRISPR gene editing, but is more precise and versatile — it “directly writes new genetic information into a specified DNA site,” according to the paper.

Oct 25, 2019

The Ouroboros Code: Bridging Advanced Science and Transcendental Metaphysics

Posted by in categories: biological, cosmology, ethics, existential risks, genetics, nanotechnology, neuroscience, quantum physics, robotics/AI, science, singularity, transhumanism, virtual reality

By contemplating the full spectrum of scenarios of the coming technological singularity many can place their bets in favor of the Cybernetic Singularity which is a sure path to digital immortality and godhood as opposed to the AI Singularity when Homo sapiens is retired as a senescent parent. This meta-system transition from the networked Global Brain to the Gaian Mind is all about evolution of our own individual minds, it’s all about our own Self-Transcendence. https://www.ecstadelic.net/top-stories/the-ouroboros-code-br…etaphysics #OuroborosCode


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Oct 25, 2019

Gut instincts: Researchers discover first clues on how gut health influences brain health

Posted by in categories: biotech/medical, genetics, health, neuroscience

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell’s Ithaca campus.

Over the last two decades, scientists have observed a clear link between and a variety of psychiatric conditions. For example, people with autoimmune disorders such as (IBD), psoriasis and multiple sclerosis may also have depleted gut microbiota and experience anxiety, depression and mood disorders. Genetic risks for autoimmune disorders and psychiatric disorders also appear to be closely related. But precisely how gut health affects brain health has been unknown.

“Our study provides new insight into the mechanisms of how the gut and brain communicate at the molecular level,” said co-senior author Dr. David Artis, director of the Jill Roberts Institute for Research in Inflammatory Bowel Disease, director of the Friedman Center for Nutrition and Inflammation and the Michael Kors Professor of Immunology at Weill Cornell Medicine. “No one yet has understood how IBD and other chronic gastrointestinal conditions influence behavior and mental health. Our study is the beginning of a new way to understand the whole picture.”

Oct 24, 2019

NIH and Gates Foundation lay out ambitious plan to bring gene-based treatments for HIV and sickle cell disease to Africa

Posted by in categories: biotech/medical, genetics, health

Two major U.S. biomedical research funders plan to each put at least $100 million over 4 years toward bringing cutting-edge, gene-based treatments to a part of the world that often struggles to provide access to even basic medicines: sub-Saharan Africa. The National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation today announced the unusual collaboration to launch clinical trials for gene-based cures for HIV and sickle cell disease within the region in the coming decade.

The ambitious goal is to steer clear of expensive, logistically impractical strategies that require stem cell transplantation, and instead develop simpler, affordable ways of delivering genes or gene-editing drugs that can cure these diseases. “Yes, this is audacious,” NIH Director Francis Collins said during a press teleconference this morning on the project. “But if we don’t put our best minds, resources, and visions together right now, we would not live up to our mandate to bring the best science to those who are suffering.”

After decades of work and setbacks, the traditional gene therapy approach of delivering DNA into the body to replace a defective gene or boost a protein’s production is now reaching the clinic for several diseases, including inherited blindness, neuromuscular disease, and leukemia. Animal studies and some clinical trials have suggested that two diseases prevalent in Africa, HIV and sickle cell disease, can be treated by gene therapies or newer genome-editing tools such as CRISPR.