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Category: computing – Page 719

Metabolic perceptrons for neural computing in biological systems

Synthetic biological circuits are promising tools for developing sophisticated systems for medical, industrial, and environmental applications. So far, circuit implementations commonly rely on gene expression regulation for information processing using digital logic. Here, we present a different approach for biological computation through metabolic circuits designed by computer-aided tools, implemented in both whole-cell and cell-free systems. We first combine metabolic transducers to build an analog adder, a device that sums up the concentrations of multiple input metabolites. Next, we build a weighted adder where the contributions of the different metabolites to the sum can be adjusted. Using a computational model fitted on experimental data, we finally implement two four-input perceptrons for desired binary classification of metabolite combinations by applying model-predicted weights to the metabolic perceptron. The perceptron-mediated neural computing introduced here lays the groundwork for more advanced metabolic circuits for rapid and scalable multiplex sensing.

Researchers Demonstrate The World’s First Quantum Radar

Yes, we know that sometimes it feels like they just tack the word quantum on new technology and call it a day like we are all living in the Marvel Cinematic Universe. Nevertheless, quantum technology is very real and is just as exciting. Our better understanding of the quantum world and handle on the principals will help us improve everything from computing to encryption.

Researchers advance organ-on-chip technology to advance drug development

Researchers from Carnegie Mellon University (CMU) and Nanyang Technological University, Singapore (NTU Singapore) have developed an organ-on-an-electronic-chip platform, which uses bioelectrical sensors to measure the electrophysiology of the heart cells in three dimensions. These 3D, self-rolling biosensor arrays coil up over heart cell spheroid tissues to form an “organ-on-e-chip,” thus enabling the researchers to study how cells communicate with each other in multicellular systems such as the heart.

The organ-on-e-chip approach will help develop and assess the efficacy of drugs for disease treatment—perhaps even enabling researchers to screen for drugs and toxins directly on a human-like , rather than testing on animal tissue. The platform will also be used to shed light on the connection between the heart’s and disease, such as arrhythmias. The research, published in Science Advances, allows the researchers to investigate processes in cultured cells that currently are not accessible, such as tissue development and cell maturation.

“For decades, electrophysiology was done using cells and cultures on two-dimensional surfaces, such as culture dishes,” says Associate Professor of Biomedical Engineering (BME) and Materials Science & Engineering (MSE) Tzahi Cohen-Karni. “We are trying to circumvent the challenge of reading the heart’s electrical patterns in 3D by developing a way to shrink-wrap sensors around heart cells and extracting electrophysiological information from this tissue.”

Quantum radar has been demonstrated for the first time

One of the advantages of the quantum revolution is the ability to sense the world in a new way. The general idea is to use the special properties of quantum mechanics to make measurements or produce images that are otherwise impossible.

Much of this work is done with photons. But as far as the electromagnetic spectrum is concerned, the quantum revolution has been a little one-sided. Almost all the advances in quantum computing, cryptography, teleportation, and so on have involved visible or near-visible light.

Complex quantum teleportation achieved for the first time

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Austrian and Chinese scientists have succeeded in teleporting three-dimensional quantum states for the first time. High-dimensional teleportation could play an important role in future quantum computers.

Researchers from the Austrian Academy of Sciences and the University of Vienna have experimentally demonstrated what was previously only a theoretical possibility. Together with quantum physicists from the University of Science and Technology of China, they have succeeded in teleporting complex high-dimensional quantum states. The research teams report this international first in the journal Physical Review Letters.

In their study, the researchers teleported the of one photon (light particle) to another distant one. Previously, only two-level states (“qubits”) had been transmitted, i.e., information with values “0” or “1”. However, the scientists succeeded in teleporting a three-level state, a so-called “qutrit”. In , unlike in classical computer science, “0” and “1” are not an ‘either/or’ – both simultaneously, or anything in between, is also possible. The Austrian-Chinese team has now demonstrated this in practice with a third possibility “2”.

DARPA’s Handheld Nuclear Fusion Reactor

fusionsunLast year, Pentagon mad science arm DARPA was working on one of its wildest projects yet: a microchip-sized nuclear reactor. The program is now officially done, the agency says. But these sorts of far-out projects have a habit of being reemerging under new managers and new names.

The project, known as the “Chip-Scale High Energy Atomic Beams” program, is an effort aimed at working on the core technologies behind a tiny particle accelerator, capable of firing subatomic particles at incredible speeds. It’s part of a larger DARPA plan to reduce all sorts of devices to microchip-scale – including cryogenic coolers, video cameras and multi-purpose sensors. All of the projects are ambitious (this is DARPA, after all). But this had to be the most ambitious of the lot. Here’s how DARPA’s plans for fiscal year 2009 described it:

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Gene editing turns cells into minicomputers that can record data

Gene editing can turn living cells into minicomputers that can read, write and perform complex calculations. The technology could track what happens inside the body over time.

DNA computers have been around since the 1990s, when researchers created DNA molecules able to perform basic mathematical functions. Instead of storing information as 0s and 1s like digital computers do, these computers store information in the molecules A, C, G and T that make up DNA.

‘Electron pairing’ found well above superconductor’s critical temperature

Physicists have found “electron pairing,” a hallmark feature of superconductivity, at temperatures and energies well above the critical threshold where superconductivity happens.

Rice University’s Doug Natelson, co-corresponding author of a paper about the work in this week’s Nature, said the discovery of Cooper pairs of electrons “a bit above the critical temperature won’t be ‘crazy surprising’ to some people. The thing that’s more weird is that it looks like there are two different energy scales. There’s a higher energy scale where the pairs form, and there’s a lower energy scale where they all decide to join hands and act collectively and coherently, the behavior that actually brings about superconductivity.”

Electrical resistance is so common in the modern world that most of us take it for granted that computers, smartphones and warm up during use. That heating happens because electricity doesn’t flow freely through the metal wires and silicon chips inside the devices. Instead, flowing electrons occasionally bump into atoms or one another, and each collision produces a tiny bit of heat.