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Category: biotech/medical – Page 97

Clinical trial shows taking blood pressure medication at night improves nocturnal and daytime control

Research led by Sichuan University in China has revealed that bedtime antihypertensive medication dosing improves nocturnal blood pressure control over morning dosing in patients with hypertension.

Hypertension is a major global health challenge. In China, nearly 300 million individuals live with elevated blood pressure and fewer than 17% achieve adequate control. Nocturnal pressure is often the most difficult to manage and can be a better predictor of heart attack and stroke than daytime readings.

Previous studies have examined the optimal timing for antihypertensive medication with conflicting evidence and substantial variability in study outcomes.

New gene tool leads to better treatments for complex diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what’s changed can be difficult.

But in a study of traits that offer clues to a person’s —such as lipid and and inflammation—a team of researchers at Case Western Reserve University devised a and tool to improve how genes and genetic changes that cause diseases are identified.

Their new approach could allow doctors to detect and treat so-called cardiometabolic diseases earlier in their development. Their findings were recently published in the journal Nature Communications.

Vertex Presents Positive Data for Zimislecel in Type 1 Diabetes at the American Diabetes Association 85th Scientific Sessions

– Results from the study continue to demonstrate the transformative potential of zimislecel with consistent and durable patient benefit – – All 12 patients with at least one year of follow-up who received a full dose of zimislecel as a single infusion achieved ADA –recommended target HbA1c levels…

Antibiotic resistance predicts higher mortality risk in 17-year follow-up—linked to diet and gender

A population-based study led by the University of Turku, Finland, investigated factors associated with the prevalence of antibiotic resistance. In addition to antibiotic use, diet, gender, living environment, income level and certain gut bacteria were associated with a higher burden of resistance. A higher resistance burden was associated with a 40% higher risk of all-cause mortality during the follow-up.

Antibiotic-resistant bacteria cause more than one million deaths per year worldwide, and the number is rising fast.

A recent study shows that an increase in relative mortality risk can be predicted by high resistance burden as well as by elevated blood pressure or type 2 diabetes. The number of antibiotic resistance genes found in gut bacteria predicted the risk of sepsis or death during a long follow-up period of almost two decades.

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