Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 936

Researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure.

In a study published in Circulation, researchers from the University of Tsukuba have shown that changing heart cell programming by tweaking the expression of a few key genes can actually reverse the lasting damage caused by heart attacks.

Adult heart cells have very limited ability to form new heart tissue, so when the is damaged by a , the damaged areas are filled in with inflexible scar tissue. The presence of scar tissue impairs and leads to arrhythmias, progressive and eventual death.

Read more | >

Their work has numerous potential impacts, especially in the context of understanding and responding to autoimmune disorders and inflammation.

ALSO READ: Man dies of heart attack watching Avatar 2; what cardiologists say

While our immune system serves a very important function protecting us from infection and injury, when immune responses become too aggressive this can lead to damaging inflammation, which occurs in conditions such as rheumatoid arthritis and psoriasis. Inflammation is triggered when our bodies produce “alarm proteins” (interleukins), which ramp up our defenses against infection and injury by switching on different components of our immune system.

Read more | >

Researchers at UC San Francisco (UCSF) have engineered molecules that act like “cellular glue,” allowing them to direct in precise fashion how cells bond with each other. This discovery represents a major step toward building tissues and organs, a long-sought goal of regenerative medicine [1].

Longevity. Technology: Adhesive molecules are found naturally throughout the body, holding its tens of trillions of cells together in highly-organised patterns. They form structures, create neuronal circuits and guide immune cells to their targets. Adhesion also facilitates communication between cells to keep the body functioning as a self-regulating whole.

Now a new study, published in Nature, details how the researchers engineered cells containing customised adhesion molecules that bound with specific partner cells in predictable ways to form complex multicellular ensembles.

Read more | >

Biophysist and Biochemist Dr. Maximilian Plach talks about a groundbreaking new technology for editing genes, called CRISPR-Cas9. The tool allows scientists to make precise edits to DNA strands, which could lead to treatments for genetic diseases … but could also be used to create so-called “designer babies.” Max reviews how CRISPR-Cas9 works — and asks the scientific community to pause and discuss the ethics of this new tool. Max has earned his PhD in biophysics and computational biology at the University of Regensburg, Germany. He is now Chief Scientific Officer of 2bind, a dynamic and growing company focused on providing biophysical research services for biotech and pharma industries. It is therefore no wonder that Max closely follows the latest breakthroughs and developments in biotech and biomedical technology. He is a long viewer and listener of TED talks; the more exotic, the better. Or who doesn’t remember the talk about the world’s worst city flags? This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

Read more | >

Awareness about aging and early symptom of disease can extend life to much more year.

There has been plenty going on here at Lifespan.io, so we thought it was time to give you a little update on what’s been happening.

Longevity Summit

The Longevity Summit 2022 is happening on December 6–7 at the Buck Institute for Research on Aging, and Lifespan.io is an official media partner! As a special bonus to our readers, you can purchase tickets here with a 15% discount using the code LifespanIO.

Continue reading “Raising Awareness that Aging is a Problem Worth Solving” | >

Researchers at the Wyss Institute at Harvard University have engineered the first-ever “Vagina on a Chip” in the world that replicates the human vaginal tissue microenvironment in vitro, Scientific American reported on Wednesday.

It is composed of the human vaginal epithelium and underlying connective tissue cells and it replicates many of the physiological features of the vagina, according to Harvard.

Best of all, it can be inoculated with different strains of bacteria allowing researchers to study their effects on the organ’s health.

Read more | >

Synchron, a neurovascular bioelectronics medicine company, today announced publication of a first-in-human study demonstrating successful use of the Stentrode™ brain-computer interface (BCI), or neuroprosthesis. Specifically, the study shows the Stentrode’s ability to enable patients with severe paralysis to resume daily tasks, including texting, emailing, shopping and banking online, through direct thought, and without the need for open brain surgery. The study is the first to demonstrate that a BCI implanted via the patient’s blood vessels is able to restore the transmission of brain impulses out of the body, and did so wirelessly. The patients were able to use their impulses to control digital devices without the need for a touchscreen, mouse, keyboard or voice activation technology. This feasibility study was published in the Journal of NeuroInterventional Surgery (JNIS), the leading international peer-review journal for the clinical field of neurointerventional surgery, and official journal of the Society of NeuroInterventional Surgery (SNIS).

Read more | >

Winter and rainly season are worst for those who have chronic cough.even little rain increases throat pain.

This Primer by Mazzone and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of chronic cough and cough hypersensitivity. This Primer also discusses how cough hypersensitivity and chronic cough affect patients’ quality of life and future research directions for the field.

Read more | >

In a new review article published in Frontiers in Cell and Developmental Biology, researchers have suggested adding cellular enlargement to the hallmarks of aging [1].

Different cell types are known to have different shapes and sizes, which are dictated by their functions. In humans, sperm cells (male gametes) and ova (female gametes) have the smallest and largest diameters, respectively. On the other hand, some neurons are the longest cells: their axons can be over a meter long.

Nevertheless, within a specific cell type, the size variation is negligible. It has been long observed that healthy cells tend to maintain their size and that size changes are characteristic of pathological conditions. Cancer cells are often smaller than normal cells, while senescence leads to cellular enlargement [2].

Read more | >