New treatment options for neuronal diseases require better imaging techniques that will help find which patients will benefits from these treatments.
Every time a new cancer drug is announced, it represents hundreds of researchers spending years behind the scenes working to design and test a new molecule. The drug has to be not only effective, but also as safe as possible and easy to manufacture—and these researchers have to choose among thousands of possible options for its chemical structure.
But building each possible molecular structure for testing is a laborious process, even if researchers simply want to change a single carbon atom.
A new technique published by University of Chicago chemists and the pharmaceutical company Merck & Co. in the journal Science offers a way to leapfrog that process, allowing scientists to quickly and easily produce new molecules of interest.
A group of 60 scientists called for a moratorium on solar geoengineering last month, including technologies such as stratospheric aerosol injection (SAI). This involves a fleet of aeroplanes releasing aerosol particles – which reflect sunlight back to outer space – into the atmosphere, cooling down the Earth.
SAI might make the sky slightly whiter. But this is the least of our concerns. SAI could pose grave dangers, potentially worse than the warming it seeks to remedy. To understand the risks, we’ve undertaken a risk assessment of this controversial technology.
A cooler Earth means less water would be evaporating from its surfaces into the atmosphere, changing rainfall patterns. This could produce ripple effects across the world’s ecosystems – but the exact nature of these effects depends on how SAI is used. Poor coordination of aerosol release could lead to extreme rainfall in some places and blistering drought in others, further triggering the spread of diseases.
Surgery has always been the remedy for cataracts. However, a new compound might be able to clear the clouding of the lens, shows a new study.
Summary: Mouse study reveals exercise increases dopamine signaling in motor areas of the brain. The findings may explain why exercise eases symptoms of Parkinson’s disease.
Source: SfN
Exercise increases dopamine signaling in the motor areas of mice, according to research recently published in Journal of Neuroscience.
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An international team which includes University of Manchester scientists has for the first time demonstrated that nerve signals are exchanged between clogged up arteries and the brain.
The discovery of the previously unknown electrical circuit is a breakthrough in our understanding of atherosclerosis, a potentially deadly disease where plaques form on the innermost layer of arteries.
The study of mice found that new nerve bundles are formed on the outer layer of where the artery is diseased, so the brain can detect where the damage is and communicate with it.
According to a new theory by LMU chemists led by Thomas Carell, it was a novel molecular species composed of RNA
Ribonucleic acid (RNA) is a polymeric molecule similar to DNA that is essential in various biological roles in coding, decoding, regulation and expression of genes. Both are nucleic acids, but unlike DNA, RNA is single-stranded. An RNA strand has a backbone made of alternating sugar (ribose) and phosphate groups. Attached to each sugar is one of four bases—adenine (A), uracil (U), cytosine ©, or guanine (G). Different types of RNA exist in the cell: messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA).
