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Category: biotech/medical – Page 823

Israeli scientists have developed a substance that overcomes antibiotic resistance by “pricking bacteria to death,” researchers at Ben Gurion University told the Times of Israel on Friday, in a breakthrough that could help combat a major threat to global health.

The substance contains “nano needles” which have a lethal effect on bacteria, and will be developed into topical creams and antibacterial coatings for surfaces, the scientists said, noting that it has shown 90% effectiveness in killing antibiotic-resistant bacteria in lab conditions.

When bacteria stop being affected by antibiotics, it is known as antibiotic resistance, and these pathogens are sometimes colloquially called superbugs.

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Electric buses could help solve the problem. Today Bhattacharya is the CEO and co-founder of BasiGo, a mobility startup racing to electrify the city’s buses. The company is not alone. Swedish-Kenyan electric vehicle manufacturer Roam also has its eyes set on Nairobi’s mass transport sector. Both are rolling out fleets of buses this year that could mark the start of a new chapter for city’s famous matatu culture.

During the early days of the coronavirus pandemic in Nairobi, Kenya, something improbable happened: a mountain appeared. To curb the transmission of the virus, authorities called on the city’s thousands of private bus operators to cease trading. “Within three days, the air completely cleared,” recalls entrepreneur Jit Bhattacharya. “You could see Mount Kenya … crystal clear,” some 90 miles away.

Bhattacharya also saw an opportunity. Kenya produces 90% of its electricity from renewable sources – mostly geothermal and hydropower – and has surplus grid capacity, yet it imports nearly all its petroleum fuels. What if clean energy could be channeled into the transport sector? Maybe it could help the city clean up its act. Maybe Mount Kenya could become a permanent feature for Nairobi once more.

The Kenyan capital is home to over five million people, and matatus, privately owned minibuses and shared taxis, “are critical to the way people in Nairobi get around,” explains Christopher Kost, Africa program director at the Institute for Transportation and Development Policy. “In the city, we have 40% of trips on public transport.”

Continue reading “Electric buses are driving a silent revolution in Nairobi” | >

The official body charged with virus classification has released four new principles that bring order to the viral world. This provides a unified framework that will enable all viruses to be classified, something vitally needed as genome technologies continue to discover millions of new virus species.

Since the ancient civilizations of Greece and Egypt, humans have attempted to classify life on Earth by putting organisms into related groups to understand life and infer relationships.

This classification of life, or taxonomy, took a giant step forward in the 18th century when Swedish botanist Carl Linnaeus established a hierarchical classification system that grouped organisms based on common characteristics. Significantly, he developed a Latin naming system that described each organism by group (genera) and specific name (species). Higher ranks brought related genera together into families, families into orders and so on through classes, phyla and kingdoms.

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If you ask it the right questions, ChatGPT represents an incredible resource and tool. And people noticed fast — within five days it gained over 1 million users, and now Microsoft is in talks for a potential $10 billion investment in the company.

As a reporter, the hype surrounding the AI tool intrigued me, and a colleague of mine said it’s journalism chops were convincing (though only if you didn’t squint too hard to notice articles were riddle with misinformation).

Knowing that ChatGPT’s database cut off in 2021, I asked it to write a stock market story about trading trends in 2020, and in less than one minute it spat out a 400-word story that mapped out S&P 500 moves, meme stocks, and shares that rallied during the early days of the pandemic.

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Researchers from The University of Queensland have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory.

Professor Frederic Meunier from the Queensland Brain Institute said the team had identified new active compounds from the mushroom, Hericium erinaceus. This type of edible mushroom, commonly known as the Lion’s Mane Mushroom, is native to North America, Europe, and Asia. It is commonly sought after for its unique flavor and texture, and it is also used in traditional Chinese medicine to boost the immune system and improve digestive health.

Researchers have discovered lion’s mane mushrooms improve brain cell growth and memory in pre-clinical trials.

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An international team of scientists has found a way to regenerate kidneys damaged by disease, restoring function and preventing kidney failure. The discovery could drastically improve treatments for complications stemming from diabetes and other diseases.

Diabetes causes many problems in the body, but one of the most prevalent is kidney disease. Extended periods of elevated blood sugar can damage nephrons, the tiny filtering units in the kidneys, which can lead to kidney dysfunction and eventually failure.

For the new study, researchers in Singapore and Germany investigated a potential culprit – a protein known as interleukin-11 (IL-11), which has been implicated in causing scarring to other organs in response to damage.

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Over the past decade, I’ve kept a close eye on the emergence of artificial intelligence in healthcare. Throughout, one truth remained constant: Despite all the hype, AI-focused startups and established tech companies alike have failed to move the needle on the nation’s overall health and medical costs.

Finally, after a decade of underperformance in AI-driven medicine, success is approaching faster than physicians and patients currently recognize.

The next version, ChatGPT4, is scheduled for release later this year, as is Google’s rival AI product. And, last week, Microsoft unveiled an AI-powered search engine and web browser in partnership with OpenAI, with other tech-industry competitors slated to join the fray.

It remains to be seen which company will ultimately win the generative-AI arms race. But regardless of who comes out on top, we’ve reached a tipping point.

Continue reading “5 Ways ChatGPT Will Change Healthcare Forever, For Better” | >

The effects of vitamin C on clinical outcomes in critically ill patients remain controversial due to inconclusive studies. This retrospective observational cohort study evaluated the effects of vitamin C therapy on acute kidney injury (AKI) and mortality among septic patients.

Electronic medical records of 1,390 patients from an academic hospital who were categorized as Treatment (received at least one dose of 1.5 g IV vitamin C, n = 212) or Comparison (received no, or less than 1.5 g IV vitamin C, n = 1178) were reviewed. Propensity score matching was conducted to balance a number of covariates between groups. Multivariate logistic regressions were conducted predicting AKI and in-hospital mortality among the full sample and a sub-sample of patients seen in the ICU.

Data revealed that vitamin C therapy was associated with increases in AKI (OR = 2.07 95% CI [1.46–2.93]) and in-hospital mortality (OR = 1.67 95% CI [1.003–2.78]) after adjusting for demographic and clinical covariates. When stratified to examine ICU patients, vitamin C therapy remained a significant risk factor of AKI (OR = 1.61 95% CI [1.09–2.39]) and provided no protective benefit against mortality (OR = 0.79 95% CI [0.48–1.31]).

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Amount of toxin present in wheat, which is carcinogenic when heated, can be reduced and grown, new field study confirms Toast could soon be healthier after scientists grew a field of wheat genetically-edited to remove a cancer-causing chemical. Bread, when baked, produces a dangerous toxin called acrylamide, which is believed to be carcinogenic and when toasted is even more lethal.

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