If it enters the brain, one species of gum-disease-causing bacteria might trigger chemical changes linked to Alzheimer’s disease.
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Category: biotech/medical – Page 2,745
Study finds diabetes drug may prevent, slow kidney disease
A drug that’s used to help control blood sugar in people with diabetes has now been shown to help prevent or slow kidney disease, which causes millions of deaths each year and requires hundreds of thousands of people to use dialysis to stay alive.
Doctors say it’s hard to overstate the importance of this study, and what it means for curbing this problem, which is growing because of the obesity epidemic.
The study tested Janssen Pharmaceuticals’ drug Invokana. Results were discussed Sunday at a medical meeting in Australia and published by the New England Journal of Medicine.
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Liquid Blood Extracted From 42,000-Year-Old Foal Found Frozen in Siberia
Scientists in the Yakutsk region of Siberia have managed to extract samples of liquid blood from a 42,000-year-old foal that was found embedded in permafrost back in 2018. The scientists are hoping to collect viable cells for the purpose of cloning the extinct species of horse.
The male foal was discovered in the Batagaika depression on August 11, 2018. Permafrost left the remains in remarkably good shape, raising hopes that its cells could be extracted. The specimen is thought to belong to an extinct species of horse known as Lenskaya breed (also known as the Lena horse), as the Siberian Times reported last year.
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Extending Human Longevity With Regenerative Medicine
Understandably, the FDA raised concerns about the practice of parabiosis because to date, there is a marked lack of clinical data to support the treatment’s effectiveness.
Elevian
On the other end of the reputability spectrum is a startup called Elevian, spun out of Harvard University. Elevian is approaching longevity with a careful, scientifically validated strategy. (Full Disclosure: I am both an advisor to and investor in Elevian.)
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An Interview with Dr. Joan Mannick of resTORbio
A number of companies are studying and commercializing rapamycin and rapalogs, including resTORbio, a Boston-based company. Tam Hunt got in touch with Dr. Joan Mannick from the company to find out more about this promising anti-aging therapeutic.
Blagoskonny ([3], [4]) has suggested that rapamycin and rapalogs are effective anti-aging therapies today for humans as well as other animals because they arrest “quasi-programmed hypertrophy.” What are your thoughts on Blagoskonny’s theory?
I think Blagoskonny’s theory is very interesting. mTOR stimulates cell growth, and there is data that mTOR becomes hyperactive in some aging tissues. This may explain why TORC1 inhibitors have benefit in aging-related diseases.
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Drug-resistant bugs discovered in animal hospital prompts health warning
Pets in a British animal hospital have been found to be harbouring potentially lethal drug-resistant bugs that could be transferred to owners.
Tests by Public Health England (PHE) revealed three cats a dog were colonised by bacteria able to fend off Linezolid, a “last-resort” antibiotic used to treat superbugs such as MRSA (methicillin-resistant Staphylococcus aureus).
No staff or owners are known to have been taken ill as a result, however the agency last night warned veterinary surgeries to enforce proper cleaning practices after this first discovery of its kind.
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