Lifeboat Foundation

Since ancient times people have been searching for the secret of immortality. Their quest has always been, without exception, about a physical item: a fountain, an elixir, an Alchemist’s remedy, a chalice, a pill, an injection of stem cells or a vial containing gene-repairing material. It has never been about an abstract concept.

Our inability to find a physical cure for ageing is explained by a simple fact: We cannot find it because it does not exist. It will never exist.

Those who believe that someday some guy is going to discover a pill or a remedy and give it to people so that we will all live forever are, regrettably, deluded.

I should highlight here that I refer to a cure for the ageing process in general, and not a cure for a specific medical disease. Biotechnology and other physical therapies are useful in alleviating many diseases and ailments, but these therapies will not be the answer to the basic biological process of ageing.

Continue reading “Alchemy vs Networks: The cure for ageing will come — but it will not be something physical” »

Western Canada’s most futurist-oriented longevity organization, the Lifespan Society of British Columbia, has organized a first-class life extension conference, which will take place later this fall in the heart of downtown Vancouver. The Longevity and Genetics Conference 2014 offers a full-day of expert presentations, made accessible to a general audience, with keynote on the latest developments in biorejuvination by Aubrey de Grey of SENS Research Foundation. The conference will be interactive, with a panel session for audience questions, and VIP options for further interaction with speakers.

Aubrey de Grey

Who will be there? In addition to Aubrey de Grey, there are four other speakers confirmed thus far: Dr. Angela Brooks-Wilson, Head of Cancer Genetics at the Michael Smith Genome Sciences Centre at the BC Cancer Agency, Dr. S. Jay Olshansky, Board of Directors of the American Federation of Aging Research, and co-author of The Quest for Immortality: Science at the Frontiers of Aging, Dr. Clinton Mielke, former Mayo Clinic researcher and founder of the quantified self platform “infino.me”, and lastly, one of futurism’s most experienced and dedicated radical longevity advocates, Benjamin Best, who is currently Director of Research Oversight at the Life Extension Foundation. This conference is a multi-disciplinary event, engaging several points of interest and relevance in the longevity space, from the cellular, genetic science of aging, to the latest epidemiological and even demographic research. You can also expect discussion on personalized medicine and quantified self technologies, as well as big picture, sociological and philosophical, longevity-specific topics.

All around, the 2014 Longevity and Genetics conference, set to take place Saturday November 15, has a lot to offer, as does the host city of Vancouver. A recent study has indicated that a majority of Canadians, 59%, are in favor of life extension technology, with 47% expecting that science and technology will enable living until 120 by 2050. The Lifespan Society of British Columbia is keeping that momentum and enthusiasm alive and growing, and I’m glad they have organized such a high-calliber event. Tickets are currently still available. Learn more about the event and purchase tickets here.

Vancouver B.C.

Dying Twice

Of course, Ebola can be stopped: By rigorously restricting locomotion for the population. But this presupposes heavy support networks. At the present moment in time, this strategy is still feasible. However, since the disease is spreading exponentially in both number and area, very soon the resources of aid-giving nations will be overtaxed. Then the Big Dying from Ebola will be accompanied by the Big Dying from hunger and thirst due to restricted locomotion without the necessary support services.

There exist institutions that could help. But they all do not know what “dying twice” means:
FIRST: from having become untouchable and unapproachable;
SECOND: from thirst, hunger and the pangs of the disease which are intolerably ugly and stenching.
Mothers do not mind. But where are all the mothers for the dying? Even Jesus’ mother was there at the cross.

Since the disease is doubling every 3 weeks (only at some places the rate is slowed due to restricted locomotion), someone must make a “war plan.” I am sure some wonderful organizations have already done so, but they must join forces, resources and above all: information.
One joint plan must be negotiated, maybe under the auspices of the Vatican?, or the CDC?, or Castroland? It need not be the money-stripped United Nations. Only: SOON!

I have a deep respect for the aid worker who coined the phrase “dying twice”: You are an angel.
Without you, we – the world – would still be blind.

By Antonio Pasolini — GizMag

The search for more efficient tests of pharmaceuticals without animal models is taking a stride forward, with a new technology being developed in the US called Organs-on-Chips. The new miniature platform and software, which mimic the mechanical and molecular characteristics of human organs, were developed by bioengineers from the Wyss Institute for Biologically Inspired Engineering at Harvard University.

The device, about the size of a small computer memory stick, is created using microchip-manufacturing techniques. It features a porous flexible membrane that separates two channels at the center of the device. The channels are filled with living human cells and tissues cultured in a fluid that mimics the environment inside the human body. Micro-engineering and automated instrumentation allows the system to perform real-time analysis of biochemical, genetic and metabolic functions within single cells.

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By Nick Lavars — GizMag

A team of international researchers has developed a molecule capable of triggering cancer cell death by carrying chloride into cancer cell membranes. The molecule flushes the cells with salt and causes them to self-destruct, potentially paving the way for new types of anti-cancer drugs.

The international effort involves researchers from the UK, Texas and South Korea who have collaborated to develop a synthetic ion transporter with a chloride payload. Once it reaches the cancer cells, the chloride interacts with the sodium in the cell membranes and leads to its demise.

Continue reading “Synthetic molecule uses salt to trigger self-destruction of cancer cells” »

What follows is my position piece for London’s FutureFest 2013, the website for which no longer exists.

Medicine is a very ancient practice. In fact, it is so ancient that it may have become obsolete. Medicine aims to restore the mind and body to their natural state relative to an individual’s stage in the life cycle. The idea has been to live as well as possible but also die well when the time came. The sense of what is ‘natural’ was tied to statistically normal ways of living in particular cultures. Past conceptions of health dictated future medical practice. In this respect, medical practitioners may have been wise but they certainly were not progressive.

However, this began to change in the mid-19th century when the great medical experimenter, Claude Bernard, began to champion the idea that medicine should be about the indefinite delaying, if not outright overcoming, of death. Bernard saw organisms as perpetual motion machines in an endless struggle to bring order to an environment that always threatens to consume them. That ‘order’ consists in sustaining the conditions needed to maintain an organism’s indefinite existence. Toward this end, Bernard enthusiastically used animals as living laboratories for testing his various hypotheses.

Historians identify Bernard’s sensibility with the advent of ‘modern medicine’, an increasingly high-tech and aspirational enterprise, dedicated to extending the full panoply of human capacities indefinitely. On this view, scientific training trumps practitioner experience, radically invasive and reconstructive procedures become the norm, and death on a physician’s watch is taken to be the ultimate failure. Humanity 2.0 takes this way of thinking to the next level, which involves the abolition of medicine itself. But what exactly would that mean – and what would replace it?

Continue reading “The Abolition of Medicine as a Goal for Humanity 2.0” »

By Brendan I. Koerner - Wired

Because it’s so late on a Monday afternoon, there is a listless vibe inside the University of Washington lecture hall where Jim Olson is about to speak. The audience consists of a few dozen grad students struggling with end-of-day fatigue. They scarf down free chocolate-chunk cookies as they prepare to take notes, but sugar can sharpen mental alertness only so much. The talk they’ve come to hear, part of a biweekly series on current topics in neuroscience, doesn’t exactly seem like edge-of-your-seat material.

Olson’s first slide wakes them up. It is a pixelated photograph of an adorable 6-year-old boy named Hayden Strum, who sports a white Quiksilver T-shirt and a pirate-style eye patch. Hayden, who suffered from a pernicious brain tumor, came to Olson in 1995, back when Olson was just starting his career as a pediatric oncologist and cancer researcher. For four years, the doctor treated Hayden with successive rounds of chemotherapy and major surgeries, but nothing could save the boy’s life. Olson tells the audience that while sitting in the back row at Hayden’s memorial service, listening to the speakers express their pain, he had an epiphany about his scientific priorities.

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We live in world, where technological advances continually allow new and provocative opportunities to deeply explore every aspect of our existence. Understanding the human brain remains one of our most important challenges– but with 100 billion neurons to contend with, the painstakingly slow progress can give the impression that we may never succeed. Brain mapping research unlocks secrets to our mental, social and physical wellness.

In our upcoming releases for the Galactic Public Archives, noted American PhD Neuroscientist and Futurist, Ken Hayworth outlines why he feels that mapping the brain will not be a quixotic task. Through this, he reveals his unconventional plan to ensure humanity’s place in the universe—forever.

We admit to teasing you with the below link in preparation for the main events.

Singularity University

In the last century, breakthroughs in modern medicine have driven big gains in quality and length of life. Antibiotics, immunization, imaging and radiology, complex surgery, minimally invasive surgery—and more. It’s a long, impressive list.

But what will the next hundred years bring?

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