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In an astonishing breakthrough, patients left paralysed by severe spinal cord injuries have recovered the ability to move their legs after training with an exoskeleton linked to their brain – with one even able to walk using two crutches.

Scientists developed the Walk Again Project, based in Sao Paulo, Brazil, thinking that they could enable paraplegics to move about using the exoskeleton controlled by their thoughts. But they were surprised to discover that during the training, the eight patients all started to regain the sense of touch and movement below the injury to their spine. It was previously thought that the nerves in seven of the patients’ spines had been completely severed.

But the researchers now believe that a few nerves survived and these were reactivated by the training, which may have rewired circuits in the brain. Writing in the journal Scientific Reports, they said: “While patient one was initially not even able to stand using braces when placed in an orthostatic posture, after 10 months of training the same patient became capable of walking using a walker, braces and the assistance of one therapist. “At this stage, this patient became capable of producing voluntary leg movements mimicking walking, while suspended overground.

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The U.S. Department of State’s Office of the Science and Technology Adviser to the Secretary of State along with the Kavli Foundation; the U.S. National Science Foundation and the Global Partnerships Forum hosted the event that launched the brain initiative during the 71st Session of the UN General Assembly to elevate brain science as a foreign policy priority.

The International Brain Initiative aims to foster coordination of large-scale brain projects around the world in partnership with governments, research institutions, private sector, foundations, advocacy groups, and social innovators.

Toward this end, the United States with Japan, Germany, Argentina and the UN Conference on Trade and Development announced the launch of the International Brain Initiative, part of which is a virtual International Brain Station to enhance and facilitate global collaboration on both basic and disease-focused brain science research.

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A brief introduction about brain research.

The human brain is more complex and has far more capacity than a billion dollar computer. So far the research done on the brain is still in its nascent stages. What mysteries and secrets it holds for humanity in the future remains one of the big questions.

The 21st century has been called the “Century of the Mind”. Research into the functions and capabilities of the wonderful organ that is the human brain will skyrocket with duration as mankind enters a new era in discovery and invention.

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University of Houston researchers aim to leverage a new, noninvasive brain-machine interface system that taps into human brainwaves to control and command a wearable exoskeleton—a technology that could enable paraplegic kids to walk.

Kristopher Sturgis

Exoskeleton University of Houston

A new study out of the Laboratory for Noninvasive Brain-Machine Interface Systems at the University of Houston (UH) has paved the way for a new exoskeleton technology that will be unveiled at Cybathlon in Zurich — an event where the world’s most innovative prosthetic and assistive technologies are unveiled. Jeffrey Gorges, researcher at the university and lead research technician on the project, says that the powered wearable robot has application possibilities for patients of any age suffering from lower-limb paraplegia, but the focus is moving toward a system for children.

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New Delhi [India]: Knee replacement technology has undergone sea change with years passing by.

With time and progress in technology the surgeons and researchers are constantly working towards achieving perfection in each surgery. One such example is ‘Computer Navigated Knee Replacement Surgery.’

Pinless Computer Navigated Total Knee Replacement technology is used by Dr Anil Arora, the head of unit and lead consultant of department of Orthopedics at Max Super Specialty Hospital, for Knee Replacement, in North India.

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Microsoft has announced to solve’ cancer within the next decade by ‘reprogramming’ diseased cells like computer virus.

Researchers were able to prevent the death of neurons that causes ALS by introducing a genetic mutation to prevent the SOD1 protein from clumping.

The growing resistance of Gonorrhea, alarmed the researchers.

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Awesome; how about Elephant tusks, etc.


In Brief.

California biotech company Pembient has announced its production of synthetic rhino horns, in the hopes of providing an ethical alternative to purchasing from poachers. Conservationist groups express worries over any unintended impact.

Although everyone was thrilled at the birth of a white rhinoceros calf, the fact still remains that the rhino is one of the world’s most endangered animals in the world (3 out of 5 species are critically endangered). This is largely due to intense poaching, which targets the rhino for its distinctive horns.

Just like checking your bag on a commercial airline, space travel comes with some pretty big weight restrictions. How big? According to estimates, reaching space costs a whopping $10,000 per pound, which means that every ounce saved has a big impact on the bottom line.

That’s where a group of Danish researchers comes in. The team is working on a synthetic biology project called CosmoCrops, which hopes to use bacteria to make it possible to 3D print everything needed for a respectable space mission, using a cutting-edge co-culturing system. And it could even make life better for those of us back on Earth in the process.

“We are trying to make space exploration cheaper, because many inventions we use in our daily life were invented because of space exploration, like Velcro and solar energy,” Joachim Larsen, one of the students working on the project, told Digital Trends. “The way we want to achieve this is to [be] able to produce everything from food to medicine and bioplastic for 3D printers out in space — making the space rocket a lot lighter.”

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In a recent experiment, a Swedish scientist, Fredrik Lanner, a developmental biologist at the Karolinska Institute in Stockholm, attempted to modify the genes of a human embryos injecting a gene-editing tool known as CRISPR-Cas9 into carefully thawed five human embryos donated by couples who had gone through in vitro fertilization (IVF). One did not survive the cooling and thawing process, while another one was severely damaged while being injected. The remaining three embryos, which were two-days old when they were injected, survived in good shape, with one of them dividing immediately after being injected.

Scientists have viewed modifying a human embryo as over the line for safety and ethical concerns. The fear is that Lanner’s work could open the door to others attempting to use genetically modified embryos to make babies. One mistake could introduce a new disease in the human gene pool that can be inherited by future generations. Scientists are also concerned on the possibility of “designer babies,” where parents could choose traits they want for their babies.

Fredrik Lanner (right) of the Karolinska Institute in Stockholm and his student Alvaro Plaza Reyes examine a magnified image of an human embryo that they used to attempt to create genetically modified healthy human embryos. (Credit: Rob Stein/NPR)

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A team of researchers at MIT and other institutions have developed miniature freeze-dried pellets that possess all of the molecular machinery required to convert DNA into proteins, which could form the basis for on-demand production of vaccines and drugs.

The pellets, which hold several enzymes and other molecules extracted from cells, can be stored for prolonged period of time at room temperature. When water and freeze-dried DNA are added, the pellets start to produce proteins encoded by the DNA.

It’s a modular system that can be programmed to make what you need, on the spot. You could have hundreds of different DNA pellets you can add in the field.

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