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UK researchers from five major universities close in on a cure for HIV by reprogramming immune cells to recognize the virus and destroy it.


A British man could become the first person in the world to be cured of HIV using a new therapy designed by a team of scientists from five UK universities.

The 44-year-old is one of 50 people currently trialling a treatment which targets the disease even in its dormant state.

Scientists told The Sunday Times that presently the virus is completely undetectable in the man’s blood, although that could be a result of regular drugs. However if the dormant cells are also cleared out it could represent the first complete cure. Trial results are expected to be published in 2018.

I never get tired in circuitry thread and any new findings.


Tufts University engineers say that revolutionary health diagnostics may be hanging on a thread—one of many threads they have created that integrate nano-scale sensors, electronics and microfluidics into threads ranging from simple cotton to sophisticated synthetics. “We think thread-based devices could potentially be used as smart sutures for surgical implants, smart bandages to monitor wound healing, or integrated with textile or fabric as personalized health monitors and point-of-care diagnostics,” says Sameer Sonkusale, Ph.D., director of the interdisciplinary Nano Lab in the Department of Electrical and Computer Engineering at Tufts School of Engineering, Medford/Somerville, Mass.

Researchers dipped a variety of conductive threads in physical and chemical sensing compounds and connected them to wireless electronic circuitry. The threads, sutured into tissues of rats, collected data on tissue health (pressure, stress, strain and temperature), pH and glucose levels. The data helps determine how wounds are healing, whether infection is emerging or whether the body’s chemistry is out of balance. Thread’s natural wicking properties draw fluids to the sensing compounds. Resulting data is transmitted wirelessly to a cell phone and computer.

To date, substrates for implantable devices have been two-dimensional, expensive and difficult to process, making them suitable for flat tissue, such as skin, but not for organs. “By contrast, thread is abundant, inexpensive, thin and flexible, and can be easily manipulated into complex shapes,” says Pooria Mostafalu, Ph.D., postdoctoral research fellow with the Harvard-MIT Division of Health Sciences and Technology and former Tufts doctoral student.

More progress in repairing damage to the cornea which could have implications for aging research as well as for injury.


Media Contacts: Suzanne Day Media Relations, Mass. Eye and Ear 617−573−3897 [email protected]

New findings may pave the way for the development of pharmaceutical therapies to reverse corneal scarring

Boston, Mass. — In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery — until now. In a study published online today in Stem Cell Reports, researchers from Schepens Eye Research Institute of Massachusetts Eye and Ear have identified hepatocyte growth factor (HGF), secreted by MSCs, as the key factor responsible for promoting wound healing and reducing inflammation in preclinical models of corneal injury. Their findings suggest that HGF-based treatments may be effective in restoring vision in patients with severely scarred corneas.

Nice.


Researchers have come up with a way for making functional neurons directly from human skin cells, including those taken from patients with Alzheimer’s disease. Alzheimer’s Reading Room Asa Abeliovich The new method may offer a critical short cut for generating neurons for replacement therapies of the future, according to research published in the August 5th …“Scientists Make Neurons Directly From Human Skin”

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Nice POV read.


We know that emerging innovations within cutting-edge science and technology (S&T) areas carry the potential to revolutionize governmental structures, economies, and life as we know it. Yet, others have argued that such technologies could yield doomsday scenarios and that military applications of such technologies have even greater potential than nuclear weapons to radically change the balance of power. These S&T areas include robotics and autonomous unmanned system; artificial intelligence; biotechnology, including synthetic and systems biology; the cognitive neurosciences; nanotechnology, including stealth meta-materials; additive manufacturing (aka 3D printing); and the intersection of each with information and computing technologies, i.e., cyber-everything. These concepts and the underlying strategic importance were articulated at the multi-national level in NATO’s May 2010 New Strategic Concept paper: “Less predictable is the possibility that research breakthroughs will transform the technological battlefield … The most destructive periods of history tend to be those when the means of aggression have gained the upper hand in the art of waging war.”

As new and unpredicted technologies are emerging at a seemingly unprecedented pace globally, communication of those new discoveries is occurring faster than ever, meaning that the unique ownership of a new technology is no longer a sufficient position, if not impossible. They’re becoming cheaper and more readily available. In today’s world, recognition of the potential applications of a technology and a sense of purpose in exploiting it are far more important than simply having access to it.

While the suggestions like those that nanotechnology will enable a new class of weapons that will alter the geopolitical landscape remain unrealized, a number of unresolved security puzzles underlying emerging technologies have implications for international security, defense policy, deterrence, governance, and arms control regimes.

Still keeping my optics working looking for news to apply to your cyberpunk games and writings.

A way to defend against counterfeit drugs and maybe food too, miniature edible barcodes. Inexpensive, practical and readable with a slight modification of a smart phone.

For some reason, the idea of edible food wrappers just seems very cyberpunk to me. Full of advertising and nutrition!

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How we can use CRISPR/Cas9 to treat the processes of aging.


Oliver Medvedik, Cofounder of the Life Extension Advocacy Foundation and the Lifespan.io Crowdfunding platform, discusses the CRISPR/Cas9 gene editing system in depth and highlights how it may be used to help overcome the diseases and disabilities of aging. He also gives an overview of other promising areas in aging research, such as senescent cell-clearing drugs, or “senolytics”, and “augmentive” compounds that may help restore the body to youthful functionality.

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