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In a stunning scientific feat in the field of cryonics, a team from Fudan University in Shanghai achieved a monumental breakthrough by successfully reviving a human brain that had been frozen for as long as 18 months. This record breaking achievement not only shatters previous records in cryogenic technology but has also been published in the esteemed academic journal Cell Reports Methods.

The team led by Shao Zhicheng created a revolutionary cryopreservation method, dubbed MEDY, which preserves the structural integrity and functionality of neural cells, allowing for the preservation of various brain tissues and human brain specimens. This advancement holds immense promise not only for research into neurological disorders but also opens up possibilities for the future of human cryopreservation technology.

Professor Joao Pedro Magalhaes from the University of Birmingham K expressed profound astonishment at the development, hailing the technology’s ability to prevent cell death and help preserve neural functionality as nothing short of miraculous. He speculated that in the future, terminally ill patients could be cryopreserved, awaiting cures that may emerge, while astronauts could be frozen for interstellar travel, awakening in distant galaxies.

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AI holds the potential to help doctors find early markers of disease and policymakers to avoid decisions that lead to war. But a growing body of evidence has revealed deep flaws in how machine learning is used in science, a problem that has swept through dozens of fields and implicated thousands of erroneous papers.

Scientists put their heads together for an insane medical breakthrough.

Neuroscience and biomedical engineering startup BrainBridge announced that it has created an AI-mechanized system for performing head transplants.

The procedure would graft a head onto the body of a brain-dead donor, maintaining the memories, cognitive abilities and consciousness of the transplanted individual.

Columbia University researchers have found cells inside clogged arteries share similarities with cancer and aggravate atherosclerosis, raising the possibility that anticancer drugs could be used to treat atherosclerosis and prevent heart attacks.

Their study found that smooth muscle cells that normally line the inside of our arteries migrate into atherosclerotic plaques, change their cell identity, activate cancer genes, and proliferate inside the plaques.

“Our study shows that these transformed muscle cells are driving atherosclerosis, opening the door to new ways to treat the disease, potentially with existing cancer drugs,” says Muredach Reilly, MD, the Florence and Herbert Irving Endowed Professor of Medicine at Columbia University Vagelos College of Physicians and Surgeons and director of Columbia’s Irving Institute for Clinical and Translational Research.

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Dr. Melvin Vopson’s study delves into the intriguing concept of information entropy, which differs from traditional physical entropy. Physical entropy measures the disorder within a system’s physical states, whereas information entropy pertains to the arrangement and complexity of information within those states.

Vopson applied this principle to the SARS-CoV-2 virus, analyzing its mutations through an information entropy lens. He explained, “The physical entropy of a given system is a measure of all its possible physical microstates compatible with the macrostate…the additional entropy associated with them is called the entropy of information.”

Unlike physical entropy, which tends to increase, Vopson observed that information entropy in the virus decreased over time. This finding led him to propose the second law of info-dynamics, suggesting that information entropy must remain constant or decrease, offering a fresh perspective on how information evolves within physical systems.

In a pioneering achievement, a research team led by experts at Cincinnati Children’s have developed the world’s first human mini-brain that incorporates a fully functional blood-brain barrier (BBB).

This major advance, published May 15, 2024, in Cell Stem Cell, promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer’s disease, Huntington disease, Parkinson’s disease, and other neurodegenerative conditions.

“Lack of an authentic human BBB model has been a major hurdle in studying neurological diseases,” says lead corresponding author Ziyuan Guo, PhD, “Our breakthrough involves the generation of human BBB organoids from human pluripotent stem cells, mimicking human neurovascular development to produce a faithful representation of the barrier in growing, functioning brain tissue. This is an important advance because animal models we currently use in research do not accurately reflect human brain development and BBB functionality.”