Hypertension is an increasingly encountered condition in modern society, as sedentary lifestyles, poor diet, and other unhealthy lifestyle choices are becoming more prevalent.
The aging processes generally cause our blood pressure to rise, as they steadily clog our arteries, stiffen blood vessels, and cause our hearts to work harder to get blood to all our tissues. However, the rate at which this happens is subject to a great deal of variation, and diet and lifestyle are two big influences on this. At least initially, hypertension is frequently self-inflicted and something that we can reverse to a certain extent, as a new study shows.
Researchers have recently demonstrated that a program seeking to help people change their lifestyles through diet and exercise was almost as effective as some medications for reducing blood pressure.
As the Equifax hack last year showed, there’s a lack of legislation governing what happens to data from a breach. And ultimately, a breach of genetic data is much more serious than most credit breaches. Genetic information is immutable: Vigna points out that it’s possible to change credit card numbers or even addresses, but genetic information cannot be changed. And genetic information is often shared involuntarily. “Even if I don’t use 23andMe, I have cousins who did, so effectively I may be genetically searchable,” says Ram. In one case, an identical twin having her genetic data sequenced created a tricky situation for her sister.
This week, DNA testing service MyHeritage revealed that hackers had breached 92 million of its accounts. Though the hackers only accessed encrypted emails and passwords — so they never reached the actual genetic data — there’s no question that this type of hack will happen more frequently as consumer genetic testing becomes more and more popular. So why would hackers want DNA information specifically? And what are the implications of a big DNA breach?
One simple reason is that hackers might want to sell DNA data back for ransom, says Giovanni Vigna, a professor of computer science at UC Santa Barbara and co-founder of cybersecurity company Lastline. Hackers could threaten to revoke access or post the sensitive information online if not given money; one Indiana hospital paid $55,000 to hackers for this very reason. But there are reasons genetic data specifically could be lucrative. “This data could be sold on the down-low or monetized to insurance companies,” Vigna adds. “You can imagine the consequences: One day, I might apply for a long-term loan and get rejected because deep in the corporate system, there is data that I am very likely to get Alzheimer’s and die before I would repay the loan.”
MyHeritage doesn’t offer health or medical tests, but many companies, like 23andMe and Helix, do. And there are plenty of players interested in DNA: researchers want genetic data for scientific studies, insurance companies want genetic data to help them calculate the cost of health and life insurance, and police want genetic data to help them track down criminals, like in the recent Golden State Killer case. Already, we lack robust protections when it comes to genetic privacy, and so a genetic data breach could be a nightmare. “If there is data that exists, there is a way for it to be exploited,” says Natalie Ram, a professor of law focusing on bioethics issues at the University of Baltimore.
The connection between food and memory is one of those fundamentally human experiences we can all relate to. A compelling new study from the University of Southern California has revealed an intriguing explanation behind this phenomenon, and it illustrates how strongly the “second brain” in our gut communicates with our brain.
Inside our gastrointestinal tract lies a massive mesh of neurons often referred to as our “second brain.” While this neuronal control system primarily works to independently manage our digestive system, it also has been found to directly communicate with the brain via a long nerve, called the vagus nerve.
The vagus nerve has been found to mediate a great deal of metabolic communication between the gut and the brain. For example, one recent study revealed how feeding behavior, modulated by activity in the hippocampus, is directly activated by vagal nerve stimulation, mediated by signals from the gastrointestinal tract.
Replacing potatoes or rice with pulses can lower your blood glucose levels by more than 20 per cent, according to a first-ever University of Guelph study.
Prof. Alison Duncan, Department of Human Health and Nutritional Sciences, and Dan Ramdath of Agriculture and Agri-Food Canada, found that swapping out half of a portion of these starchy side dishes for lentils can significantly improve your body’s response to the carbohydrates.
Replacing half a serving of rice with lentils caused blood glucose to drop by up to 20 per cent. Replacing potatoes with lentils led to a 35-per-cent drop.
Really excited to announce our new initiative to make early-stage rejuvenation therapies more accessible.
Our mission is to enable people to vastly extend their healthy lifespan and be part of the first generation to cure aging.
We support the development of rejuvenation therapies that undo the damage of aging by funding basic research, bringing together the world’s leading scientists at our annual Undoing Aging conference and helping startups that work on actual therapies for human use.
In addition, we are developing our ‘Personal Longevity Strategy’ which harnesses the enormous wealth of the world’s cutting-edge medical knowledge to empower people to make informed decisions about extending their healthy lifespan right now.
We were interested to learn that Juvenescence Limited, a biotech and development company involved in the development of therapies that target the aging processes, has successfully raised $50 million in a series A financing round.
Jim Mellon, the chairman of Juvenescence Limited, said, “We are delighted with the progress we have made and the faith that investors have placed in us to build a world-class company, one that we hope will lead the field in longevity science for the benefit of humanity as well as yield superb returns for our shareholders. Our company ethos is to advance the science that will add years of healthy life to every human being, and that is exactly what we are executing on at record speed.”
Juvenescence has raised $63 million from various international investors since its creation in October 2016 and is now moving forward with a number of key projects. The company is comprised of a number of industry leaders in business as well as a solid scientific team led by Dr. Declan Doogan and Dr. Annalisa Jenkins.
Two recently published studies are raising new concerns that the breakthrough CRISPR-Cas9 gene editing system could potentially trigger an increased cancer risk in cells edited using the technique. With human trials using the gene-editing technique set to commence this year, the scientists behind these new studies urge researchers to be aware of this newly discovered and dangerous cancer-driving mechanism.
It has been less than a decade since the revolutionary CRISPR-Cas9 gene-editing technique was discovered, allowing scientists an unprecedented way to accurately edit DNA. For the most part, the technique has proved promising, safe and effective. Last year, a controversial study was published claiming the technique could introduce unintended, off-target mutations, but after a flurry of criticism attacking the veracity of the work it was ultimately retracted.
These two new studies raise entirely new concerns regarding the technique’s potential for triggering cancer in edited cells. One study comes from a collaboration between the University of Cambridge and the Karolinska Institutet, while the other is led by a team of researchers at pharmaceutical company Novartis.
Eventually all petroleum-based material in food packaging will have to be replaced with bio-based material. Research done at Karlstad University shows that a mixture of starch and other polymers forms an equally effective protective barrier.
“Food packaging has to protect and extend the shelf life of food, and should also work during transport,” says Asif Javed, doctor in Chemical Engineering at Karlstad University. “To meet these demands, a protective barrier is needed in paper-based packing such as those used for juice or dairy.”
