Nov 26, 2016
Researchers put mouse embryos in suspended animation
Posted by Steve Hill in categories: biotech/medical, life extension
Hitting the pause button on development in embryos has implications for understanding aging.
UC San Francisco researchers have found a way to pause the development of early mouse embryos for up to a month in the lab, a finding with potential implications for assisted reproduction, regenerative medicine, aging, and even cancer, the authors say.
The new study—published online November 23, 2016 in Nature —involved experiments with pre-implantation mouse embryos, called blastocysts. The researchers found that drugs that inhibit the activity a master regulator of cell growth called mTOR can put these early embryos into a stable and reversible state of suspended animation.
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