Biotech/medical – Lifeboat News: The Blog

Jun 4
2020

Europe bets R&D spending will bring jobs to battered economy

The European Union wants a massive dose of research spending to lift it out of what could be the worst recession in its history. Last week, as part of a €1.85 trillion budget and pandemic recovery proposal, the European Commission, the EU executive arm, unveiled plans to pump €94.4 billion into research over 7 years, nearly €11 billion more than originally planned for the program, called Horizon Europe. But not everyone thinks the money is the best medicine.

Horizon Europe gets €13.5 billion to spend fast, spur growth.

Jun 4
2020

A Digital Locksmith Has Decoded Biology’s Molecular Keys

Neural networks have been taught to quickly read the surfaces of proteins — molecules critical to many biological processes. The advance is already being used to create defenses for the virus responsible for COVID-19.

Jun 4
2020

How DNA and RNA subunits might have formed to make the first genetic alphabet

Understanding the prebiotic origins of the nucleic acids is a long-standing challenge. The latest experiments support the idea that the first nucleic acid encoded information using a mixed ‘alphabet’ of RNA and DNA subunits. RNA and DNA nucleosides might have emerged together on prebiotic Earth.

Jun 3
2020

Up to 81% of COVID-19-Positive Patients are Asymptomatic: Study

In a paper published in the journal Thorax, a team of Australia researchers described the first instance of complete COVID-19 testing of all passengers and crew on an isolated cruise ship during the current pandemic: of the 217 passengers and crew on board, 128 tested positive for COVID-19 on reverse transcription-PCR; of the COVID-19-positive patients, only 24 (19%) were symptomatic.

Jun 3
2020

Tiny Human Livers Grown in The Lab Have Been Successfully Transplanted Into Rats

Scientists have successfully transplanted functional miniature livers into rats, after growing the bioengineered organs in the lab from reprogrammed human skin cells.

The experiment, which gave the animals working liver organs, could lay the groundwork for future treatments to address terminal liver failure – a disease that claims the lives of over 40,000 people in the US every year.

While there’s still a lot of work to be done before the technique can directly aid human patients, the researchers say their proof of concept may help underpin a future alternative to liver transplants, which are often incredibly expensive procedures to perform, in addition to being strictly limited by donor supply.

Jun 3
2020

Investigational COVID-19 Convalescent Plasma

Although promising, convalescent plasma has not yet been shown to be safe and effective as a treatment for COVID-19. Therefore, it is important to study the safety and efficacy of COVID-19 convalescent plasma in clinical trials.

Pathways for use of investigational COVID-19 convalescent plasma

The following pathways are available for administering or studying the use of COVID-19 convalescent plasma:

Jun 3
2020

IM’s issue # 5

Immortalists magazine issue no. 5 is out smile

It is predicted that a pandemic of psychological and societal injuries is to come as we face financial and emotional crises across the globe.

Jun 3
2020

Lab-grown mini-livers bring us closer to an organ donor-free future

In a fascinating new study, scientists created fully-functional mini-livers out of human skin cells, then successfully transplanted them into rats.

The research is a proof-of-concept for potentially revolutionary technology and provides a glimpse of an organ donor free future.

Jun 3
2020

Fauci: Moderna COVID-19 Phase III Trial to Begin in July with 30,000 Patients

“That’s very early,” Anna Durbin, a vaccine researcher at Johns Hopkins University, told STAT. “We don’t know if those antibodies are durable.”

The Moderna press release also indicated that the antibody levels observed were equal to or greater in the 100 ug dose than was seen in patients who recovered from COVID-19. There’s not much context here, because studies on recovered COVID-19 patients have shown a range that is potentially influenced by the severity of the disease. For example, John “Jack” Rose, a Yale University vaccine researcher told STAT about a study in China demonstrating that in 175 recovered COVID-19 patients, 10 had no detectable neutralizing antibodies, while others had very high antibody levels.

Of the Phase III trial, Fauci indicated that the majority of trial participants will be between the ages of 18 and 55, but will include elderly Americans that are most at risk of serious illness from COVID-19.

Jun 3
2020

Handheld UV Light Devices That Kill COVID-19, Other Viruses May Soon Be As Common As Phone, Keys

UNIVERSITY PARK, Pa. — Phone, keys, wallet…ultraviolet light device. Just in case you wanted yet another item to carry around all day, researchers say that portable, handheld COVID-19 killing ultraviolet light devices may be a reality in the future. These gadgets would emit high-intensity ultraviolet light and quickly disinfect targeted areas.

There are two main ways to clean and remove bacteria and viruses from a given surface: chemicals and ultraviolet (UV) radiation exposure. UV radiation between 200 and 300 nanometers can effectively kill a virus and stop it from replicating itself. Obviously, devices emitting UV rays would come in handy these days due to COVID-19, but as of now such devices require an expensive, bulky mercury-containing gas discharge lamp with a short battery life.

The study’s authors, however, believe that much more portable, longer lasting, energy efficient, and environmentally friendly UV light emitting diodes can be developed. The necessary LEDs already exist, but the process has been complicated by the fact that electrode materials must also be transparent.