Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,361

After successfully transplanting the first 3D-printed cornea in an animal, North Carolina company Precise Bio has recently announced the launch of a dedicated business for creating marketable, 3D-printed products for human eyes. Founded by scientists from the Wake Forest Institute of Regenerative Medicine, this company is developing bio-fabrication printers that can restore cells, tissues, and organs. Their proprietary technology, a 4D bio-printing platform, is said to resolve existing limitations presented by other bioprinters to enable more complex tissues to be engineered for transplants and treatments. By focusing on developing marketable products for the eye, the company aims to achieve rapid advancement in its field and move to overhaul the whole organ transplant system.

When a cornea is damaged by disease or injury, a replacement is often needed to restore vision. Transplant surgery using donated corneas is an available solution, however, it relies on a deceased donor. While the waiting list in the United States is nearly non-existent, other countries require longer wait times, some over a year, before one is available. The Eye Bank Association of America estimates that around 10 million people suffer from corneal blindness that could potentially be restored via transplant surgery. An artificially manufactured cornea would overcome supply limitations while also contributing to the knowledge base to develop more complex organs such as hearts and livers.

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If you think you’ve got a bad case of the travel bug, get this: Dr. John Halamka travels 400,000 miles a year. That’s equivalent to fully circling the globe 16 times.

Halamka is chief information officer at Harvard’s Beth Israel Deaconess Medical Center, a professor at Harvard Medical School, and a practicing emergency physician. In a talk at Singularity University’s Exponential Medicine last week, Halamka shared what he sees as the biggest healthcare problems the world is facing, and the most promising technological solutions from a systems perspective.

“In traveling 400,000 miles you get to see lots of different cultures and lots of different people,” he said. “And the problems are really the same all over the world. Maybe the cultural context is different or the infrastructure is different, but the problems are very similar.”

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Heart disease is the leading cause of death in the U.S.

The American Heart Association and the American College of Cardiology, who have medical experts from around the nation on the writing committee, have released updated guidelines on managing cholesterol to minimize the risk of heart attack, stroke, and death. The new guidelines advocate for more aggressive treatment with statin therapy and getting LDL cholesterol counts, commonly referred to as “bad cholesterol” to your target level –- in general, less than 100mg/dL; for those with risk factors, less than 70mg/dL.

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The number of children being stricken by a mysterious paralyzing condition continues to increase, federal officials say.

At least 252 cases of acute flaccid myelitis, or AFM, have been reported to the Centers for Disease Control and Prevention so far this year from 27 states, including 90 that have been confirmed through Nov. 9, the CDC reported Tuesday.

Most of the cases have occurred among children between the ages of 2 and 8.

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Researchers from the Kapahi Lab at the Buck Institute for Research on Aging have shown in a new study that increased intestinal permeability is caused by the age-related loss of epithelial cells that form the gut membrane [1].

As we age, the integrity of the gut membrane declines, and it becomes more permeable; this is known as “leaky gut” and is thought to contribute to the background of low-grade chronic inflammation known as inflammaging [2]. One emerging theory is that loss of gut membrane integrity is the origin of inflammaging, the place where age-related chronic inflammation begins. Inflammaging precedes many age-related diseases, including atherosclerosis, arthritis, hypertension, and cancer [3–5].

The new study suggests that caloric restriction, or caloric restriction mimetics, may help to prevent the increase of gut permeability in humans and has the potential to increase healthspan, which is the period of life we spend free from illness.

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Privacy advocates have raised concerns about patients’ data after Google said it would take control of its subsidiary DeepMind’s healthcare division.

Google, which acquired London-based artificial intelligence lab DeepMind in 2014, said on Tuesday that the DeepMind Health brand, which uses NHS patient data, will cease to exist and the team behind its medical app Streams will join Google as part of Google Health.

It comes just months after DeepMind promised never to share data with the technology giant and an ethics board raised concerns over its independence.

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