Insulin will be beyond the reach of around half of the 79 million people expected to be living with diabetes in 12 years time, a new study predicts.
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Category: biotech/medical – Page 2333
We wanted to bring your attention to a recent publication that discusses the topic of cellular senescence and the contributions of senescent cells to aging and disease [1].
What is perhaps the most interesting part of this paper is the section covering the potential future directions that researchers may take in managing senescent cell populations in order to mitigate age-related disease.
The author writes not only about the direct destruction of senescent cells via senolytic drugs but also about the modulation of the harmful secretions these cells produce, which are called the senescence-associated secretory phenotype (SASP).
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People with the rare and fatal brain disorder Creutzfeldt-Jakob disease (CJD) show signs of the disease in their eyes, according to a new study.
The study found evidence of prions — the infectious proteins that cause the disease — in the eyes of nearly a dozen patients with CJD.
The findings suggest that patients’ eyes could potentially provide a “window” to the brain that may help researchers diagnose the disease early, if new eye tests are developed. [’Eye’ Can’t Look: 9 Eyeball Injuries That Will Make You Squirm].
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On January 29–31, 2019, the Longevity Therapeutics Summit is happening at the Argonaut Hotel in San Francisco, California. The conference is a great networking opportunity with some leading names in aging research giving talks during the event.
This will be a two-day conference plus a pre-conference workshop hosted by our good friend Kelsey Moody from Ichor Therapeutics. During the workshop, Kelsey will be giving his personal insights into launching and developing a successful biotech company, particularly the challenges faced in the field of rejuvenation biotechnology. This is sure to be a highly informative workshop and well worth your time, especially if you are interested in launching your own company in this field, but even if you are not, it may still prove interesting to learn about this challenging industry.
This conference aims at bringing together leading figures in biology, biotechnology, omics, investment, and other fields in order to discuss how to further accelerate progress in aging research so that the time between basic research and clinical use is as short as possible.
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Bionic Vision Technologies, a firm based in Australia, has announced that its bionic eye system has been used to restore a “sense of sight” to four completely blind people suffering from retinitis pigmentosa. The findings from the study, which was performed at Royal Victorian Eye and Ear Hospital in Melbourne, were presented at the Royal Australian and New Zealand College of Ophthalmologists Scientific meeting.
Unlike previous studies of the technology that were limited to in-lab use, the four patients were able to use the system in their everyday environments.
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The company will have to wrestle more seriously with ethical questions as it expands into new industries and countries. These include Japan, where it’s making road-tracking software to help steer driverless Hondas, and the U.S., where its New Jersey health lab is developing cancer detection software. It’s also working to bring interactive games to livestreamers in Southeast Asia, teaming up with the popular app Bigo.
SenseTime, the world’s most valuable AI startup, aims to bring its smarter-cameras-everywhere model, well, everywhere.
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Scientists in Fife are investigating if tiny lasers could be used to better understand diseases such as cancer.
Using nano-technology, the St Andrews University experts created lasers small enough to fit inside live cells which can then be tracked.
With a diameter of a thousandth of a millimetre, the lasers can be inserted into neurons or immune cells.
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One of the strangest things that can sicken us—a rogue misfolded protein that destroys the brain, known as a prion—is even scarier than we knew. Researchers were able to find the prions responsible for sporadic Creutzfeldt-Jakob disease (sCJD), the most common prion disease in people, seeded everywhere in the eyes of 11 patients affected by it.
The findings are the latest to suggest that these universally fatal, if rare, diseases can be spread through the eyes. But they also indicate that our eyes might be someday be used to spot these cases with less hassle than current testing methods.
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Experts increasingly think a system that could help paralyzed patients is within reach.
- By Sharon Begley, STAT on November 20, 2018
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A time to fast
Posted in biotech/medical, economics, genetics, life extension, neuroscience
! A new review on the positive effects on lifespan and health of fasting and calorie restriction.
Nutrient composition and caloric intake have traditionally been used to devise optimized diets for various phases of life. Adjustment of meal size and frequency have emerged as powerful tools to ameliorate and postpone the onset of disease and delay aging, whereas periods of fasting, with or without reduced energy intake, can have profound health benefits. The underlying physiological processes involve periodic shifts of metabolic fuel sources, promotion of repair mechanisms, and the optimization of energy utilization for cellular and organismal health. Future research endeavors should be directed to the integration of a balanced nutritious diet with controlled meal size and patterns and periods of fasting to develop better strategies to prevent, postpone, and treat the socioeconomical burden of chronic diseases associated with aging.
The worldwide increase in life expectancy has not been paralleled by an equivalent increase in healthy aging. Developed and developing countries are facing social and economic challenges caused by disproportional increases in their elderly populations and the accompanying burden of chronic diseases. Geriatricians and gerontologists have contributed greatly to our understanding of the consequences and processes that underlie aging from clinical, social, mental, physical, and biological perspectives. The primary goal of aging research is to improve the health of older persons and to design and test interventions that may prevent or delay age-related diseases. Besides socioeconomic status, energy, environmental quality, and genetics are the most powerful determinants of health and longevity. Although environmental quality and genetics are not under our direct control, energy intake is.
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