Lifeboat Foundation

Rice University scientists and collaborators at Texas A&M University and University of Texas MD Anderson Cancer Center have found a new way to kill cancer cells by using near-infrared light to make a small dye molecule attached to their membrane vibrate strongly. It is the first time this kind of mechanical molecular action has been used as a potential therapy.

A special form of molecule has been found to “tear apart” the membranes of cancer cells once activated, a promising new study by scientists at Rice University in Texas has revealed.

Known as aminocyanine molecules – and commonly used as synthetic dyes in medical imaging – their atoms can vibrate in unison and form a “plasmon” when hit with near-infrared light, causing cancer cells’ membranes to rupture.

And this treatment – through the use of what researchers are calling “molecular jackhammers” – is unbelievably effective, going by the study’s results.

Innovative quantum-inspired imaging technique excels in low-light conditions, offering new prospects in medical imaging and art conservation.

Researchers at the University of Warsaw’s Faculty of Physics with colleagues from Stanford University and Oklahoma State University have introduced a quantum-inspired phase imaging method based on light intensity correlation measurements that is robust to phase noise. The new imaging method can operate even with extremely dim illumination and can prove useful in emerging applications such as in infrared and X-ray interferometric imaging and quantum and matter-wave interferometry.

Revolutionizing Imaging Techniques

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require specificity for particular protein homologs. Typically, larger biologics that can target these proteins demand injection, limiting patient convenience and accessibility.

In a new study published in Nature Chemical Biology, scientists from the laboratory of Professor Christian Heinis at EPFL have achieved a significant milestone in drug development. Their research opens the door to a new class of orally available drugs, addressing a long-standing challenge in the pharmaceutical industry.

“There are many diseases for which the targets were identified but drugs binding and reaching them could not be developed,” says Heinis. “Most of them are types of cancer, and many targets in these cancers are protein-protein interactions that are important for the tumor growth but cannot be inhibited.”

Body scan companies say they can diagnose cancer faster and that AI can make it cheaper. But there’s a gap between that dream and the medical community’s reality.

ETH Zurich researchers have shown for the first time that microvehicles can be steered through blood vessels in the brains of mice using ultrasound. They hope that this will eventually lead to treatments capable of delivering drugs with pinpoint precision.

This year gave rise to an incredible mix of brain implants that can record, decode, and alter brain activity.

It sounds like déjà vu—brain-machine interfaces also lived rent free in my head in last year’s roundup, but for good reason. Neuroscientists are building increasingly sophisticated and flexible electronic chips that seamlessly integrate machine intelligence with our brains and spinal cords at record-breaking speed. What was previously science fiction—for example, helping paralyzed people regain their ability to walk, swim, and kayak—is now reality.

This year, brain implants further transformed people’s lives. The not-so-secret sauce? AI.

RENGE is a computational method that infers gene regulatory networks using time-series single-cell CRISPR data as input.

Polarization is one of the fundamental characteristics of electromagnetic waves. It can convey valuable vector information in sensitive measurements and signal transmission, which is a promising technology for various fields such as environmental monitoring, biomedical sciences, and marine exploration. Particularly in the terahertz frequency range, traditional device design methods and structures can only achieve limited performance. Designing efficient modulator devices for high-bandwidth terahertz waves presents a significant challenge.

Researchers led by Prof. Liang Wu at Tianjin University (TJU), China, have been conducting experiments in the field of all-dielectric metamaterials, specifically focusing on utilizing these materials and their structural design to achieve effective broadband polarization conversion in the terahertz frequency range.

They propose a cross-shaped microstructure metamaterial for achieving cross-polarization conversion and linear-to-circular polarization conversion in the terahertz frequency range. The study, titled “An all-silicon design of a high-efficiency broadband transmissive terahertz polarization convertor,” was published in Frontiers of Optoelectronics.