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Category: biotech/medical – Page 2,187

Higher serum levels of elaidic acid, an objective biomarker for industrial trans fat, are associated with an increased risk for developing all-cause dementia and Alzheimer disease, according to a study published online Oct. 23 in Neurology.

Takanori Honda, Ph.D., from Kyushu University in Fukuoka, Japan, and colleagues examined the prospective correlation between serum elaidic acid (trans 18:1 n-9) levels and incident dementia in 1,628 Japanese community residents aged 60 years and older without dementia. Participants underwent screening examination in 2002 to 2003 and were followed prospectively to November 2012.

The researchers found that 377 participants developed some type of dementia during follow-up. After adjustment for traditional risk factors, significant correlations were seen for higher serum elaidic acid levels with greater risk for developing all-cause dementia and Alzheimer disease. After adjustment for dietary factors, including total energy intake and intakes of saturated and , these associations remained significant. There was no significant correlation noted for serum elaidic acid levels and vascular dementia.

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A chance finding ten years ago led to the creation by researchers of the Spanish National Cancer Research Centre (CNIO) of the first mice born with much longer telomeres than normal in their species. Given the relationship between telomeres and ageing – telomeres shorten throughout life, so older organisms have shorter telomeres -, scientists launched a study generating mice in which 100% of their cells had hyper-long telomeres. The findings are published in Nature Communications and show only positive consequences: the animals with hyper-long live longer in better health, free from cancer and obesity. The most relevant thing for the authors is the fact that longevity has been significantly increased for the first time ever without any genetic modification.

“This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider”, indicates Maria Blasco, Head of the CNIO Telomeres and Telomerase Group and intellectual author of the paper. “There is margin for extending life without altering the genes”.

Telomeres form the end of chromosomes, in the nucleus of each cell in the body. Their function is to protect the integrity of the genetic information in DNA. Whenever the cells divide the telomeres, they are shortened a little, so one of the main characteristics of ageing is the accumulation of short telomeres in cells. “Telomere shortening is considered to be one of the primary causes of ageing, given that short telomeres cause ageing of the organism and reduce longevity”, as the paper published in Nature Communications explains.

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A few years ago, popular YouTuber Life Noggin published a video titled “WHY DO WE DIE?” In this video, he briefly goes into the science behind the gradual cellular degradation of the biological substrate, which causes all known side-effects associated with aging. At the end of the video, however, he revealed that he’d much rather “live forever” than die.

As a result, his subscribers, which is nearly at 2.9 million, took to the comments section to overwhelmingly declare similar hopes. Not everyone was convinced, however.

As we continue searching for the cure to aging, we’ll need to better inform the public that we’ve no intention of dictating how long they’re to live and when they’re to die.

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Prostate cancer runs in Jeff Nelson’s family. His brother, uncle and cousins have all been diagnosed with the disease. When his prostate-specific antigen (PSA) test results jumped to 5.5 from 4 in summer 2018, he knew he had to move quickly.

Jeff Nelson chose UCI Health and an investigative treatment for prostate cancer that uses high-intensity sound waves to destroy only the cancer tissue. He’s glad he did.

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We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

Kevin Strange discussed his company, Novo Biosciences, and how it is developing small molecules that restore the body’s ability to regenerate. He went into detail about how humans begin life with this ability but lose it as they age. He discussed MSI-1436, which is a prospective drug for reversing ischemic heart injury and making life easier for survivors of heart attack as well as reversing skeletal muscle degeneration.

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Good news for the MitoMouse project! Thanks to the support of the community, LongeCity has already agreed to donate several thousand dollars to the MitoMouse campaign. It plans to expand this support, fully funding the stretch goal of $75,000 if we are able to reach the first $65,000 goal.

With just $1460 left to go before we reach the first stretch goal, your donation is critical in making these stretch goals a reality – and bringing about the end of mitochondrial dysfunction that much sooner! There are only a few days left in this campaign, so if you haven’t already donated, now is the time!

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Dr. Nick interviews Liz Parrish, the Founder, and CEO of BioViva Sciences USA Inc at RaadFest in Las Vegas. Nick Delgado, ABAAHP is one of the leading experts in the field of bio-identical hormones, herbs, nutrition, exercise, partner intimacy, mindful self-motivation. Our goal is to help you restore your cellular health to radically improve the quality of life and world health.
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Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures.
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Continue reading “Curing biological Aging & Gene Therapy with Liz Parrish and Dr. Nick Delgado at RaadFest, Las Vegas” | >

OmniVision, a developer of advanced digital imaging solutions, has announced that it has won a place in the Guinness Book of World Records with the development of its OV6948 image sensor—it now holds the record for the smallest image sensor in the world. Along with the sensor, the company also announced the development of a camera module based on the sensor called the CameraCubeChip.

In its announcement on the company website, representatives of OmniVision suggest the main use for the new sensor and module is for medical applications. They claim the camera module can be affixed to disposable endoscopes to capture high-resolution images of very tiny parts of the body via such as nerves, eye parts, the heart, the spine, gynecological areas, inside joints and in parts of the urological system.

Reps for the company note that the U.S. Food and Drug Administration has recently pointed out that cross-contamination issues related to the reuse of endoscopes requires prevention. The new camera, when used with new disposable endoscopes, solves the problem by removing the need to reuse such devices.

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