Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2185

Wang and his colleagues found that many cancers that get switched into overdrive and boost tumor growth have jumping genes that function as a kind of stealthy “on switch.” These cryptic switches can force a gene to be turned on all the time, even though it should be off.

Mistakes in DNA are known to drive cancer growth. But a new study, from Washington University School of Medicine in St. Louis, heavily implicates a genetic phenomenon commonly known as “jumping genes” in the growth of tumors.

The study is published March 29 in the journal Nature Genetics.

Since jumping genes aren’t mutations—mistakes in the letters of the DNA sequence—they can’t be identified by traditional cancer genome sequencing. As such, this study opens up new lines of research for future cancer therapies that might target such genes.

Continue reading “‘Jumping genes’ drive many cancers” | >

After being sold out this year with nearly 500 participants, we will be back in 2020!

Already missing us? Subscribe to the Undoing Aging YouTube channel to get notified when the UA2019 speaker presentations are released: youtube.com/c/UndoingAging

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What happens when Earth’s resources run out? Well, if science fiction has taught us anything, it’s that humanity will seek a new and habitable planet somewhere in the cosmos on which to keep the species going in perpetuity. When that day comes, we’ll need a viable way to procreate and deliver children in the vastness of outer space.

Enter SpaceLife Origin, a one-of-a-kind tech company that is seeking to make it possible for humans to give birth in the vacuum of space by 2024, a goal titled “Mission Cradle.” While that is its ultimate goal, SpaceLife is also striving to become the first company to “safe-guard human ‘Seeds-of-Life’ in space [Mission Ark] by 2020 [and] make embryo conception in space feasible [Mission Lotus] by 2021,” according to its official website.

The gallery below offers a glimpse at the patent-pending “Ark” designs. Vials of human DNA will be protected within the radiation-shielded spheres that are to be kept on Earth and satellites surrounding the planet. SpaceLife Origin describes this as an insurance policy for the continuation of mankind in case a catastrophe hits and we need to leave in a hurry.

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Red blood cells are amazing. They pick up oxygen from our lungs and carry it all over our body to keep us alive. The hemoglobin molecule in red blood cells transports oxygen by changing its shape in an all-or-nothing fashion. Four copies of the same protein in hemoglobin open and close like flower petals, structurally coupled to respond to each other. Using supercomputers, scientists are just starting to design proteins that self-assemble to combine and resemble life-giving molecules like hemoglobin. The scientists say their methods could be applied to useful technologies such as pharmaceutical targeting, artificial energy harvesting, ‘smart’ sensing and building materials, and more.

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“If I can bring forward the defeat of aging even one day, I would have saved the lives of 110,000 people.” – Dr. Aubrey de Grey at EmTech Asia 2019.

The age-old quest for immortality was largely confined to the myths and legends of past civilizations until about just two decades back when telomerase, the active component for the gene that confers immortality to cells was successfully isolated in a science laboratory. That turned the tide on the entire conversation from whether aging could be treated, to how it could be treated.

Since then it has spawned a whole new medical field – ‘healthspan’ – where scientific research is conducted with the aim of extending healthy human lives for as long as hundreds and thousands of years, if not outright immortality. It is not surprising that the intensive research into anti-aging technologies has attracted financial backing from those who are interested in technological progress – the tech community, the likes of Google and even cryptocurrency tycoons such as Ethereum Founder, Vitalik Buterin, who donated $2.4 million worth of ether to the nonprofit foundation SENS Research Foundation, of which Dr Aubrey de Grey is the Chief Science Officer.

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