Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,064

Across Earth’s history, our planet has been home to an estimated 109 billion human beings. And according to another oft-repeated factoid, half of all the people who have ever existed were killed by malaria, the worst mosquito-borne illness. Mosquitoes aren’t merely annoyances, they are mass murderers.

But is this actually true?

There’s little doubt that these hellacious insects are prodigious killers of humankind. The bloodsuckers spread all sorts of diseases – West Nile Virus, various kinds of Encephalitis, Dengue Fever, Yellow Fever, and Zika Virus, for example. However, the damage wrought by all of these diseases is piddling in comparison to malaria. Causing fever, tiredness, vomiting, headaches, and seizures, it struck 216 million people in 2016 alone, resulting in between 445,000 to 731,000 deaths. Believe it or not, that’s an improvement over past years. In 2000, there were 262 million cases, resulting in at least 839,000 deaths.

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Public health officials have confirmed the first U.S. case of a mysterious coronavirus that has sickened hundreds of people in China, the Centers for Disease Control and Prevention said Tuesday.

A Snohomish County, Washington State resident who was returning from China on Jan. 15 was diagnosed with the Wuhan coronavirus, according to the CDC.

Officials said the patient, a male in his 30s, is “very healthy.” He is currently being isolated at a medical center in the state “out of caution” and “poses little risk” to the public, they said. The CDC said the man reached out to local health authorities last week once he started experiencing pneumonia-like symptoms.

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This year marks the Eighth Review Conference (RevCon) of the Biological Toxins and Weapons Convention (BWC). At the same time, ongoing international efforts to further and more deeply investigate the brain’s complex neuronal circuitry are creating unprecedented capabilities to both understand and control neurological processes of thought, emotion, and behavior. These advances have tremendous promise for human health, but the potential for their misuse has also been noted, with most discussions centering on research and development of agents that are addressed by existing BWC and Chemical Weapons Convention (CWC) proscriptions. In this article, we discuss the dual-use possibilities fostered by employing emergent biotechnologic techniques and tools—specifically, novel gene editors like clustered regular interspaced short palindromic repeats (CRISPR)—to produce neuroweapons. Based on our analyses, we posit the strong likelihood that development of genetically modified or created neurotropic substances will advance apace with other gene-based therapeutics, and we assert that this represents a novel—and realizable—path to creating potential neuroweapons. In light of this, we propose that it will be important to re-address current categorizations of weaponizable tools and substances, so as to better inform and generate tractable policy to enable improved surveillance and governance of novel neuroweapons.

Keywords: : CRISPR, Gene editing, Neuroweapon, Neurotherapeutic pathways, Dual-use neuroscience, Biosecurity policy.

T his year marks the Eighth Review Conference (RevCon) of the Biological Toxins and Weapons Convention (BWC), the purpose of which is to ensure that the convened parties’ directives continue to be relevant to and viable for prohibiting the development, production, and stockpiling of biological weapons in the face of newly emerging scientific advancements and biotechnologies. Apropos of issues raised at previous RevCons and elsewhere, there are growing concerns about current and future weaponization of neurobiological agents and tools (ie, “neuroweapons”1–6).

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Scientists have long assumed that fungi exist mainly to decompose matter into chemicals that other organisms can then use. But researchers at the Albert Einstein College of Medicine of Yeshiva University have found evidence that fungi possess a previously undiscovered talent with profound implications: the ability to use radioactivity as an energy source for making food and spurring their growth.

“The fungal kingdom comprises more species than any other plant or animal kingdom, so finding that they’re making food in addition to breaking it down means that Earth’s energetics—in particular, the amount of radiation energy being converted to biological energy—may need to be recalculated,” says Dr. Arturo Casadevall, chair of microbiology & immunology at Einstein and senior author of the study, published May 23 in PLoS ONE.

The ability of fungi to live off radiation could also prove useful to people: “Since ionizing radiation is prevalent in outer space, astronauts might be able to rely on fungi as an inexhaustible food source on long missions or for colonizing other planets,” says Dr. Ekaterina Dadachova, associate professor of nuclear medicine and microbiology & immunology at Einstein and lead author of the study.

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