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Category: biotech/medical – Page 1914

A team of researchers affiliated with multiple institutions in China and one in Korea has developed a micro-robot system that regenerated knee cartilage in rabbits. In their paper published in the journal Science Advances, the group describes their system and how well it worked.

In many developed countries, the population is growing older, which means aging-related health conditions are on the rise. One such ailment common in older people is degeneration of the in the knees and hips. When this happens, a common treatment is replacing the knee or hip joint with an artificial device. In this new effort, the researchers have found a better way to handle the problem—regrowing the cartilage.

Prior research has shown that found in and fat can be coaxed into growing into cartilage cells. And researchers have also found that stem cells can be used to repair damaged cartilage. The challenge is placing the cells in the body where they are needed and keeping them in place until they attach to the surrounding tissue. In this new effort, the researchers have created a system that was able to overcome these hurdles—at least in rabbits.

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Early mammalian development is a highly complex process involving elaborate and highly coordinated biological processes. One such process is zygotic genome activation (ZGA) which occurs following the union of the sperm and egg, marking the beginning of life. The resultant early embryos, termed ‘zygotes’ are capable of generating the entire organism, a property known as totipotency.

Totipotent sit atop the developmental hierarchy and have the greatest potency of all cell types, giving it limitless therapeutic potential. Surpassing pluripotent embryonic stem cells, which are only able to differentiate into all within the embryo, the totipotent zygote loses its totipotency as it matures into pluripotency.

Scientists at the National University of Singapore’s Yong Loo Lin School of Medicine have now found a way to manipulate pluripotent cells into acquiring the totipotent capacity previously thought to exist only in the zygote. This not only provides key insights into how totipotency is formed and the earliest events in mammalian development, but opens new doors for potential cell therapies that were previously unexplored.

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About 50 years ago, scientists believed magic mushrooms and LSD held a lot of medicinal promise. So then, how did they become such a taboo to even discuss? Government officials thought that if young men were on LSD, they wouldn’t want to fight in wars.

In this video, author Michael Pollan describes the little known history of psychedelic drugs in America.

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Circa 2018

It may look like just another giant smokestack, but a 200-foot tower in the central Chinese city of Xi’an was built to pull deadly pollutants from the air rather than add more. And preliminary research shows the tower — which some are calling the world’s largest air purifier — has cut air pollution significantly across a broad swath of the surrounding area.

Given those findings, the researchers behind the project say they hope to build an even taller air-purifying tower in Xi’an, and possibly in other cities around China.

“I like to tell my students that we don’t need to be medical doctors to save lives,” said Dr. David Pui, a professor of mechanical engineering at the University of Minnesota and one of the researchers. “If we can just reduce the air pollution in major metropolitan areas by 20 percent, for example, we can save tens of thousands of lives each year.”

Continue reading “This skyscraper-sized air purifier is the world’s tallest” | >

Circa 2016 could cure viruses in no time.

When you get right down to it, developing vaccines is about data and luck. Scientists start with a set of variables—what drugs a virus responds to, how effectively, and for whom—and then it’s a whole lot of trial and error until they stumble upon a cure.

One of the most exciting possibilities in medical research right now is how technology like machine learning could help researchers rapidly process those enormous sets of data, more quickly leading to cures. This is already starting to happen: In a study published Wednesday in the journal Macromolecules, researchers from IBM and Singapore’s Institute of Bioengineering and Nanotechnology reveal a breakthrough that could help prevent deadly virus infections. With the help of IBM super computer Watson, they hope their finding will soon make its way into vaccines.

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