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Category: biotech/medical – Page 1,881

‘Smart Toilet’ Checks You for Diseases Like Cancer

A disease-detecting “precision health” toilet can sense multiple signs of illness through automated urine and stool analysis, according to a new study.

The “smart toilet” isn’t the kind that lifts its own lid in preparation for use; this toilet includes technology that can detect a range of disease markers in stool and urine, including those of some cancers, such as colorectal or urologic cancers.

The device could hold particular appeal for people genetically predisposed to certain conditions, such as irritable bowel syndrome, prostate cancer, or kidney failure, and want to keep on top of their health.

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First Accuray CyberKnife M6 System Installed in Missouri

February 27, 2020 — Accuray Incorporated announced that Mercy Hospital St. Louis continues to demonstrate its commitment to improving patient outcomes with the installation of the first CyberKnife M6 System in Missouri at their state-of-the-art David C. Pratt Cancer Center. The next-generation CyberKnife System has been shown to deliver precise stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments with ease, making it possible for the clinical team to expand access to one of the most advanced methods for administering radiation to more cancer patients.

SRS and SBRT are non-invasive forms of radiation therapy that use high doses of very targeted radiation to destroy tumors, in just a few treatment sessions (1 to 5). SRS is commonly used to treat conditions within the brain and spine, while SBRT is used for those tumors located outside these areas. The CyberKnife M6 System is equipped with sophisticated functionality that will streamline the creation of personalized treatment plans and reduce the time to deliver radiation treatments, enabling the Mercy St. Louis team to offer precision SRS and SBRT treatments to more patients each day.

The Mercy Hospital St. Louis team uses the most advanced radiotherapy technology to design and deliver an individualized treatment plan designed to help cancer patients take control of their disease and resume their lives. The hospital is part of the Mercy system, named one of the top five large U.S. health systems from 2016 to 2019 by IBM Watson Health. Mercy announced in 2018 that it intended to work with Accuray to enhance cancer care through advanced life-saving technology, including the CyberKnife System that was recently installed as well as Accuray Radixact Systems that will be installed at other Mercy hospitals.

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Anti-aging enzyme discovery raises prospect of lifespan extension

A study from researchers at KAIST (Korea Advanced Institute of Science and Technology) is providing new insights into a cellular energy pathway that has been linked to longer lifespan. The research, conducted in human cells and roundworms, raises the prospect of anti-aging therapeutics that can extend lifespan by activating this pathway.

AMPK (adenosine monophosphate-activated protein kinase) is an enzyme that acts as a metabolic master switch. It has been described as a “magic bullet” protein, conferring broad beneficial health effects, from improving cardiovascular health to extending lifespan. It is activated in response to low cellular energy levels, as is often seen during exercise or periods of caloric restriction.

An increasing volume of study has found activating AMPK in animal models leads to notable increases in lifespan, prompting a surge in research investigating this enzyme.

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ZAP Surgical to Bring World-Class Brain Tumor Treatments to Rural German Hospital

SAN CARLOS, Calif., Feb. 19, 2020 /PRNewswire/ — ZAP Surgical Systems, Inc. today announced an agreement with Bonifatius Hospital in Lingen, Germany to acquire ZAP-X® stereotactic radiosurgery (SRS) technology.

SRS is a well-known and effective procedure for non-invasively treating select brain tumors and brain metastases. However, significant acquisition and radiation shielding costs of historical SRS systems have limited widespread access to this potentially life-saving therapy. Consequently, scarce availability of SRS treatment has remained heavily concentrated in large urban hospitals.

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Silencing the SARS-CoV-2 Receptor With CRISPR and Epigenetic Modifications

The Hackett Group at EMBL Rome explores epigenetics, genome regulation and cell identity. Recently, the scientists developed a novel CRISPR molecular tool for editing the epigenome, enabling transient modifications that can switch certain genes “on” and “off” temporarily.

The SARS-CoV-2 virus that has caused the COVID-19 global pandemic makes its way into a host cell via a protein known as ACE2, which is involved in a range of physiological functions in the body.

What happens when you transiently turn “off” the gene that encodes this protein? Can SARS-CoV-2 still enter the cell and cause infection? This is what Hackett and colleagues are currently exploring in animal models, to determine whether epigenetic silencing could be a treatment approach for COVID-19 in humans.

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How AI Will Make Drug Discovery Low-Cost, Ultra-Fast, and Personalized

Life-saving Ai

If you had to guess how long it takes for a drug to go from an idea to your pharmacy, what would you guess? Three years? Five years? How about the cost? $30 million? $100 million?

Well, here’s the sobering truth: 90 percent of all drug possibilities fail. The few that do succeed take an average of 10 years to reach the market and cost anywhere from $2.5 billion to $12 billion to get there.

But what if we could generate novel molecules to target any disease, overnight, ready for clinical trials? Imagine leveraging machine learning to accomplish with 50 people what the pharmaceutical industry can barely do with an army of 5,000.

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Humans Might Be So Sickly Because We Evolved to Avoid a Single Devastating Disease

Hundreds of thousands of years ago, our ancestors evolved a simple trick that could have helped thwart a major infectious disease. It probably saved our skins, but the change was far from a perfect solution.

New research has uncovered evidence that mutations arising between 600,000 and 2 million years ago were part of a complex of adaptations that may have inadvertently made us prone to inflammatory diseases and even other pathogens.

An international team of researchers compared around a thousand human genomes with a few from our extinct cousins, the Neanderthals and Denisovans, to fill in missing details on the evolution of a family of chemicals that coat the human body’s cells.

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Start Vaccinating Now!

Sao Paulo State Governor Joao Doria displays a box of the COVID-19 vaccine produced by the Chinese company Sinovac Biotech at the Hospital das Clinicas (HC) in Sao Paulo State, during its trial stage, during a press conference in Sao Paulo, Brazil, on July 21, 2020 amid the novel coronavirus pandemic. — The vaccine trial will be carried out in Brazil in partnership with the Brazilian Research Institute Butanta. (Photo by Nelson ALMEIDA / AFP) (Photo by NELSON ALMEIDA/AFP via Getty Images)

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How AI is uncovering the ‘dark matter of nutrition’

The COVID-19 pandemic didn’t just transform how we work and communicate. It also accelerated the need for more proactive health measures for chronic health problems tied to diet. Such problems have emerged as a top risk factor for coronavirus and people with poor metabolic health accounted for half of COVID-19 hospitalizations in some regions around the world. The resulting high numbers led the authors of a report in The Lancet to issue a call for more resources to tackle metabolic health to avoid needless deaths.

Thankfully, new tools have been developed to offer comprehensive understanding of nutrition. This expertise and technology won’t just help us tackle metabolic health – it could help us finally fully realize the power of plants to improve health and wellness outcomes.

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