Researchers at the Johns Hopkins University School of Medicine, in Baltimore, MD, conducted their investigation in a new mouse model of Parkinson’s disease.
The new model replicates a number of early and late signs and symptoms of Parkinson’s disease, including some that are not movement-related.
(CNN) — Exposure to a chemical commonly used to reduce bacterial contamination in cosmetics, toothpaste and products like toys and clothing may come with an unintended risk — osteoporosis. That’s according to a study in Tuesday’s Journal of Clinical Endocrinology & Metabolism.
The study looked at data from 1,848 women between 2005 and 2010 and found that women who had higher levels of triclosan in their urine were more likely to develop osteoporosis later on in life. Osteoporosis is a metabolic bone disease in which a person loses bone mineral density. With the bones weakened, it puts a person at an increased risk for fractures, back pain and loss of height.
This the first such study to find this connection, researchers said.
Proteins dating back more than one million years have been extracted from some fossils, and could help to answer some difficult questions about archaic humans.
Today, we want to highlight a new publication that looks at cytomegalovirus (CMV) and its potential role in the development of metabolic syndrome, the precursor to type 2 diabetes.
What is cytomegalovirus?
CMV is part of the β-subfamily of herpes viruses, a family of viruses that are believed to have been co-evolving with their hosts for around 180 million years [1]. CMV is spread primarily by exposure to infected secretions and subsequent mucosal contact, which then leads to the acute infection of various cell types. After this acute infection, in which the virus spreads, it enters a dormant state in the body.
Another great addition to #RAADfest2019 #cureaging #NAD #superlongevity
Dr. Nichola Conlon, Nuchido CEO & Co-founder, chats with James Strole, Director of the Coalition for Radical Life Extension, about what she’s bringing to RAADfest 2019: Increasing NAD+ levels in middle-aged people to a level comparable with people 17 years younger with the data to back it up.
Nuchido has pioneered the use of systems pharmacology and clinical research to boost and maintain NAD. In a scientific world-first, the team achieved the biggest increase of NAD in humans reported by any scientific group.
Two recent studies highlight novel ways to combat pattern hair loss in men and women using small molecules such as JAK inhibitors that reawaken dormant hair follicles, as well as stem cell therapies aimed at growing new follicles.
In the first study, researchers led by Angela Christiano, Ph.D., the Richard & Mildred Rhodebeck Professor of Dermatology at Columbia University Vagelos College of Physicians and Surgeons, discovered previously unknown cells that keep mouse hair follicles in a resting state and show that inhibiting the activity of these cells can reawaken dormant follicles.
Individuals that are experiencing frequent migraines, may soon receive access to a new class of medications.
A pair of large studies showed that two drugs have the ability to reduce the frequency of the migraine attacks, without any side effects. The researchers report in the New England Journal of Medicine that the drugs offer the first ever migraine treatment that is aimed at the disorder itself, instead of the symptoms.
Current migraine treatments consist of drugs that are designed to treat epilepsy, depression and high blood pressure. Peter Goadsby, an author of one of the studies in question and a professor at King’s College in London says that they give the patients a choice between antidepressants that will make them sleepy, and a beta blocker, which will make them feel tired.
Until the day he died, in 2011, Robert Ettinger hoped humanity would figure out a way to cheat death. Today, his body is stored in a chamber filled with liquid nitrogen and frozen to −196 °C. He lies in cryopreservation at the Cryonics Institute in Michigan—which he founded—alongside his late mother, his first and second wives, and 150 other deceased.
Ettinger, known as the “father of cryonics,” popularized the idea in his 1962 book The Prospect of Immortality. (Isaac Asimov, the renowned biochemist and science-fiction writer, helped Ettinger publish the book.) Cryonicists believe that technology will sufficiently advance to a point where cells can be rejuvenated and the aging process reversed. In practice, legally deceased patients arrive at a cryonics facility packed in ice. Cryonicists interrupt the dying process by draining the blood from the body and perfusing the corpse with a mixture of anti-freeze and organ-preserving chemicals, known as cryoprotective agents. The body is then transformed into a vitrified state and lowered into a below-freezing chamber filled with liquid nitrogen, where it lies in wait for a future generation to restore it.