Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 1,815

Eye drop recall: Florida woman sues company after eye removed

A Florida woman is suing an eye drop manufacture claiming that its product — which has been linked to a deadly bacteria outbreak — made her legally blind.

Sixty-eight-year-old Clara Elvira Oliva is taking legal action against Global Pharma Healthcare after suffering such a severe infection from using its EzriCare Artificial Tears that she had to have her eye removed, according to court documents.

Oliva’s right eye was removed and replaced with a plastic implant in September 2022 to control a “severe antibiotic resistant infection,” according to the lawsuit filed earlier this month in Federal court in Miami, Florida.

Blood Test #2 in 2023: Diet Composition

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout.

Green Tea: https://www.ochaandco.com/?ref=conqueraging.

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten.

Epigenetic Testing: https://bit.ly/3Rken0n.
Use Code: CONQUERAGING!

At-Home Blood Testing: https://getquantify.io/mlustgarten.

Continue reading “Blood Test #2 in 2023: Diet Composition” | >

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

Your circadian rhythm doesn’t just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review paper published in the journal Trends in Cell Biology, researchers discuss the role of circadian rhythms in tumor progression and spread and describe how we could better time when patients are tested for cancer and when they receive therapies to improve diagnostic accuracy and improve treatment success.

“The circadian rhythm governs most of the cellular functions implicated in cancer progression, and therefore its exploitation opens new promising directions in the fight against metastasis,” write the authors, molecular oncologists Zoi Diamantopoulou, Ana Gvozdenovic, and Nicola Aceto from the ETH Zurich in Switzerland.

Our circadian rhythms help our bodies synchronize different tasks throughout the day, including gene expression, immune function, and cell repair. We’ve long known that chronically disrupted circadian rhythms—as a result of erratic sleep patterns, jet lag, or , for example—can predispose us to a number of health issues, including cancer. More recent work has shown that circadian rhythms are not only involved in tumor onset, but also govern and metastasis, the colonization of secondary sites within the body.

Writing the Rules on CRISPR Activation

The researchers add that these data demonstrate that CRISPRa is generally applicable across chromatin states and cell types, and highlights the factors that impact the degree of gene activation and how easy it is to reproduce the effects. Understanding these factors is important in the design and analysis of CRISPRa screens, which are used to look for genes involved in genetic diseases, the team points out.

Further study is required to continue to add to these rules and to see whether different CRISPRa or CRISPR interference techniques behave in a similar way.

“Our research has established a system for reporting the effectiveness of CRISPR activation in stem cells, allowing us to gain a better understanding of how CRISPRa works in multiple cell states,” says Qianxin Wu, PhD, first author from Wellcome Sanger. “We also showed that CRISPR gene activation is powerful enough to induce stem cells to differentiate into other cell states. This suggests that CRISPRa screens can be used to search for genes involved in cellular processes or to generate more accurate models of cell types in the body, aiding research into genetic diseases and regenerative medicine.”

5 Best Types of Video Games for TBI Rehabilitation

Who would have thought that video games are good for TBI? I play them sometimes. Time for that, and not just music.

Video games may help TBI patients recover their physical and cognitive abilities faster than traditional therapy, according to recent research.

Although they might seem like just a pleasant distraction, video games engage several parts of the brain at once and can even promote neuroplasticity.

Today’s article will explain the many therapeutic uses video games offer. Then, we will show you some of the best types of video games for TBI.

Shining a light into the ‘black box’ of AI

Researchers from the University of Geneva (UNIGE), the Geneva University Hospitals (HUG), and the National University of Singapore (NUS) have developed a novel method for evaluating the interpretability of artificial intelligence (AI) technologies, opening the door to greater transparency and trust in AI-driven diagnostic and predictive tools. The innovative approach sheds light on the opaque workings of so-called “black box” AI algorithms, helping users understand what influences the results produced by AI and whether the results can be trusted.

This is especially important in situations that have significant impacts on the health and lives of people, such as using AI in . The research carries particular relevance in the context of the forthcoming European Union Artificial Intelligence Act which aims to regulate the development and use of AI within the EU. The findings have recently been published in the journal Nature Machine Intelligence.

Time series data—representing the evolution of information over time—is everywhere: for example in medicine, when recording heart activity with an electrocardiogram (ECG); in the study of earthquakes; tracking weather patterns; or in economics to monitor financial markets. This data can be modeled by AI technologies to build diagnostic or predictive tools.