Lifeboat Foundation

One of the most astonishing revelations might be that information equals reality. In other words, the basis for our material reality is actually immaterial information. Pattern and flow of information is what defines our experiential reality.

Everything boils down to the binary code of Nature. This is a basic tenet of Digital Physics which is the science of information. Nature computes. Deep down we are information technology. We run on genetic, neural and societal codes. Our DNA-based biology is clearly code-theoretic. We are alphabetic all the way down. We communicate intersubjectively mind-to-mind via language-structured exchange of information.

A recent study shows that human speech is transmitted at about 39 bits a sec. Idealist philosopher Terence McKenna used to say that “The world is made of language and if you know the words the world is made of you can make of it whatever you wish.”

At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge.

BioAge is developing a drug discovery platform that uses machine learning and artificial intelligence to discover targets that have the potential to promote healthy lifespan (healthspan) by slowing down aging and the ill health that it brings.

As the vice president of in-vivo biology at BioAge, Dr. Rebo leads the company’s internal in-vivo platform to find and assess the viability of new druggable targets for aging diseases and biomedical regeneration. With considerable business as well as academic experience in the aging field under his belt, Justin joined the BioAge team in 2018.

A new study is the first to report evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin may lessen the adverse effects of air pollution exposure on lung function. The team of researchers from the Columbia Mailman School of Public Health, Harvard Chan School of Public Health, Boston University School of Medicine published their findings in the American Journal of Respiratory and Critical Care Medicine.

The researchers analyzed a subset of data collected from a cohort of 2,280 male veterans from the greater Boston area who were given tests to determine their lung function. The average age of participants was 73 years. The researchers examined the relationship between test results, self-reported NSAID use, and ambient particulate matter (PM) and black carbon in the month preceding the test, while accounting for a variety of factors, including the health status of the subject and whether or not he was a smoker. They found that the use of any NSAID nearly halved of the effect of PM on lung function, with the association consistent across all four weekly air pollution measurements from same-day to 28 days prior to the lung function test.

Because most of the people in the study cohort who took NSAIDs used aspirin, the researchers say the modifying effect they observed was mainly from aspirin, but add that effects of non-aspirin NSAIDs are worthy of further exploration. While the mechanism is unknown, the researchers speculate that NSAIDs mitigate inflammation brought about by air pollution.

A year old, and this video is titled with the “I-word”. But a very interesting talk.

It’s not every day that I get to post a video where I feel like I’m involved with something that may seriously improve and extend lives. I’m so grateful that somehow, I was brought into this process.

Continue reading “Immortality by 2029” »

A team of researchers from Baylor University, with assistance from staff at the Massachusetts Eye and Ear Infirmary, Harvard Medical School and the Dana-Farber Cancer Institute has developed and tested a smartphone app that is able to detect “white eye” in children by analyzing stored photographs. In their paper published in the journal Science Advances, the group describes how the app was developed and tested, and how well it works.

Most everyone has seen pictures of people seemingly possessed by the devil because their pupils glow red—this is caused by light bouncing off their retinas. However, such pictures sometimes produce white instead of red retinas. Sometimes it can happen due to ambient lighting conditions, but other times, it can indicate an eye ailment. Such problems can include retinoblastoma, a type of eye cancer, retinopathy, or even cataracts.

The idea for an app that could detect white eye came from the experience of one of the researchers, Brian Shaw, and his son, who developed retinoblastoma and subsequently lost an eye. The team developed the app and made it available to the public back in 2014, but it was not until more recently that the team decided to test the app to see how well it works.

A new study found that certain fungi can settle in the pancreas, where they spur the growth of tumors.

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Continue reading “Aubrey DE GREY, An overview of recent progress in projects of SENS Research Foundation, EHA 2018” »

Electrical engineers at Duke University have devised a fully print-in-place technique for electronics that is gentle enough to work on delicate surfaces including paper and human skin. The advance could enable technologies such as high-adhesion, embedded electronic tattoos and bandages tricked out with patient-specific biosensors.

The techniques are described in a series of papers published online July 9 in the journal Nanoscale and on October 3 in the journal ACS Nano.

“When people hear the term ‘printed electronics,’ the expectation is that a person loads a substrate and the designs for an electronic circuit into a printer and, some reasonable time later, removes a fully functional electronic circuit,” said Aaron Franklin, the James L. and Elizabeth M. Vincent Associate Professor of Electrical and Computer Engineering at Duke.

Scientists at the University of California, Berkeley have used the CRISPR gene-editing tool to give fruit flies an evolutionary advantage they’ve never had before. By making just three small changes to a single gene, the team gave the flies the ability to effectively eat poison and store it in their bodies, protecting themselves from predators in the process.

Milkweed is a common plant that’s toxic to most animals and insects – but the monarch butterfly flies in the face of that plant’s defenses. The bug has evolved the ability to not only thrive on the poisonous plant, but turn it to its own advantage. It stores the toxins in its body, making it poisonous to any predators that might try to eat it.

And now, the UC Berkeley researchers have given fruit flies that ability for the first time. CRISPR has been used to edit the genes of insects, mammals and even humans, but the team says this is the first time a multicellular organism has been edited to endow it with new behaviors and adaptations to the environment. In this case, that means a new diet and a new defense mechanism against predators.