Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1794

HONG KONG (Reuters) — Researchers at a Hong Kong university say they have developed an antiviral coating which could provide 90 days of “significant” protection against bacteria and viruses such as the one causing COVID-19.

The coating, called MAP-1, took 10 years to develop and can be sprayed on surfaces that are frequently used by the public, such as elevator buttons and handrails, researchers at the Hong Kong University of Science and Technology (HKUST) say.

“These places are frequently touched, and, at the same time, serve as a very effective medium for transmission of diseases,” said HKUST Adjunct Professor Joseph Kwan, one of the chief researchers in the team that developed the product.

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A group of researchers has demonstrated that treatment with NMN, a precursor of NAD+, restores neurovascular coupling (NVC) in aged mice [1]. Since NVC deficiency seems to be a major factor in the age-related decline of cognitive and motor functions, this discovery presents exciting new possibilities for longevity research.

Neurovascular coupling

While the human brain is the evolutionary advantage that brought us to where we are today, operating this machine requires considerable resources. Our cerebral blood flow (CBF) accounts for 15% of cardiac output and 20% of resting total oxygen consumption, even though the brain itself comprises just 2% of body mass. CBF has to be constantly redirected to the regions of the brain that are currently active, and NVC is the mechanism in charge of this complex operation. Importantly, the CBF/cardiac output ratio decreases with age [2].

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In November of 2019—likely, even earlier—a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale. Within a few months, the relentless voyager known as SARS-CoV-2 had made its way to every populated corner of the earth, leaving scientists and health authorities with too many questions and few answers.

Today, researchers are scrambling to understand where and how the novel coronavirus arose, what features account for the puzzling constellation of symptoms it can cause and how the wildfire of transmission may be brought under control. An important part of this quest will involve efforts to properly classify this emergent human pathogen and to understand how it relates to other we may know more about.

In a consensus statement, Arvind Varsani, a molecular virologist with ASU’s Biodesign Center for Fundamental and Applied Microbiomics and a host of international collaborators propose a new classification system, capable of situating coronaviruses like SARS-CoV-2 within the enormous web of viruses across the planet, known as the virosphere.

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Central to a lot of scientific research into aging are tiny caps on the ends of our chromosomes called telomeres. These protective sequences of DNA grow a little shorter each time a cell divides, but by intervening in this process, researchers hope to one day regulate the process of aging and the ill health effects it can bring. A Harvard team is now offering an exciting pathway forward, discovering a set of small molecules capable of restoring telomere length in mice.

Telomeres can be thought of like the plastic tips on the end of our shoelaces, preventing the fraying of the DNA code of the genome and playing an important part in a healthy aging process. But each time a cell divides, they grow a little shorter. This sequence repeats over and over until the cell can no longer divide and dies.

This process is linked to aging and disease, including a rare genetic disease called dyskeratosis congenita (DC). This is caused by the premature aging of cells and is where the team focused its attention, hoping to offer alternatives to the current treatment that involves high-risk bone marrow transplants and which offers limited benefits.

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Depending on who you ask and where you are, wearing a mask can be an important part of the strategy to stop the spread of SARS-CoV-2.

With the CDC recommending surgical and N95 masks should be kept for medical personnel on the front line, if you do want or need a mask, you should be purchasing or making a cloth one.

But when looking at cloth masks, which materials work best for keeping your germs in and other people’s germs out?

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Around the world, scientists race to develop a vaccine or treatment against the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, a team of researchers has found that a drug already available around the world can kill the coronavirus in a lab setting in just 48 hours.

Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID.

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During the 1918 flu, San Francisco lifted its lockdown early — and paid a dire price.
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In US news and current events today, the coronavirus pandemic, the COVID-19 outbreak has had people around the world in lockdown. People in the United States and the world at large have had to quarantine and practice social distancing and self-isolation when necessary.

Some states, like Georgia, are beginning to reopen businesses, but history has shown us that lifting a lockdown too early can have dire consequences. Here’s how San Francisco’s early lifting of regulations during the 1918 flu, a strain of H1N1 virus also referred to as the Spanish flu, nearly doubled the death toll of the city.

#Coronavirus #Lockdown #SanFrancisco #Pandemic #Flu #News #NowThis #NowThisNews

Continue reading “San Francisco Paid the Price for Lifting Spanish Flu Lockdown Early | NowThis” | >

Built in about 24 hours, this robot is undergoing in-hospital testing for coronavirus disinfection.

UV disinfection is one of the few areas where autonomous robots can be immediately and uniquely helpful during the COVID pandemic. Unfortunately, there aren’t enough of these robots to fulfill demand right now, and although companies are working hard to build them, it takes a substantial amount of time to develop the hardware, software, operational knowledge, and integration experience required to make a robotic disinfection system work in a hospital.

Conor McGinn, an assistant professor of mechanical engineering at Trinity College in Dublin and co-leader of the Robotics and Innovation Lab (RAIL), has pulled together a small team of hardware and software engineers who’ve managed to get a UV disinfection robot into hospital testing within a matter of just a few weeks. They made it happen in such a short amount of time by building on previous research, collaborating with hospitals directly, and leveraging a development platform: the TurtleBot 2.

Continue reading “Akara Robotics Turns TurtleBot Into Autonomous UV Disinfecting Robot” | >