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Most cancers are driven by continuous cell division, the cause of which is largely a mystery. Scientists at Vanderbilt University have discovered a genetic switch that seems to touch off that abnormal proliferation of cells—and they did it with the gene editing system CRISPR.

Using a genomewide CRISPR screen, the Vanderbilt team discovered that deleting a protein made by the gene TRAF3 causes cells to proliferate without stopping, even after they reach a certain density that would normally signal them to stop dividing. Because TRAF3 has not been linked to cancer before, the finding could offer key insights into the development of some cancers, the researchers reported in the journal eLife.

The team started with 40 million epithelial cells, using CRISPR to select cells that kept dividing uncontrollably. They were surprised to discover that a loss of TRAF3 activates signaling that in turn drives cell proliferation. TRAF3 normally activates immunity and had not been linked to uncontrolled cell growth before, they said.

Preclinical research demonstrates that combining the oncolytic virus CF33 with an immune checkpoint inhibitor results in lasting resistance to certain tumors such as colon cancer. City of Hope surgical oncologist Susanne Warner, M.D., senior author of the study, said the virus could be a “gamechanger.”

P.e.a.c.e!nc. is proud to announce the conclusion as finalists in the $500k Pandemic Response Challenge sponsored by Cognizant with Landmark AI Experiment.

I didn’t get my 2nd Moderna Vaccine because how sick others became after theirs — nausea, fatigue, headaches for days, lymph nodes the size of a rock that fits in your hand, increased heart rate… Recently a Utah woman died 4 days after her 2nd vaccine-her heart, liver and kidneys failed. Less then a yr ago I read several studies on hospitalized COVID patients — how their kidneys and liver were failing. I read a recent study on how post COVID individuals are now having heart issues. Another study shows how COVID attacks the heart and why such individuals are now having heart issues. In December 2020, 13 individuals died after getting vaccinated (probably more since then). There is a real connection between COVID and organ failure!!!! I wish I kept links of all the information I read. Be happy to find them again. We don’t even know the long term affects of the vaccine — are the vaccinated going to experience long term health issues as well? Take your chances with a vaccine, or not.

A Utah woman in her 30s died four days after receiving the coronavirus vaccine.

Kassidi Kurill, 39, was healthy and happy and “had more energy” than others, according to a KUTV report. Then, four days after she received her second dose of the coronavirus vaccine, she suddenly died.

“She came in early and said her heart was racing and she felt like she [needed] to get to the emergency room,” her family said. Her father, Alfred Hawley, said he woke up to her asking for help.

Many post COVID victims have heart issues. This is why:


A new study has discovered how the SARS-CoV-2 virus attacks and damages the heart, answering a long-standing question about mysterious heart conditions following COVID-19 infection. The results could have large implications on how to effectively treat severe infections and develop new therapies for preventing long-term damage.

Throughout the pandemic, people with severe COVID-19 infection have often displayed symptoms of heart distress. Those with underlying heart conditions are at a greater risk of severe illness if they catch it, and reports of abnormal heart rhythms (arrhythmia) in previously healthy patients with acute COVID-19 have been common.

However, exactly why this happens has eluded scientists until now. Researchers have been unsure whether the heart symptoms are a result of severe inflammation as the body reacts to the infection, or whether the virus particles themselves invade and attack heart cells.

Saving Lives; Changing Minds — Dr. Emanuele Capobianco, MD, Director for Health and Care, International Federation of Red Cross and Red Crescent Societies.


Dr. Emanuele Capobianco, MD, MPH, is the Director for Health and Care at the International Federation of Red Cross and Red Crescent Societies (IFRC), where he leads the IFRC Global Health and Care Team and provides strategic and operational support to 192 National Red Cross and Red Crescent Societies around the world in the areas of community health, emergency health and water/sanitation. He currently also leads the IFRC global response to COVID19 and the IFRC response to the Ebola outbreaks in DRC.

Before this role at IFRC, Dr. Capobianco was the Deputy Executive-Director of The Partnership for Maternal, Newborn & Child Health, a multi-constituency partnership, hosted by the World Health Organization, and is the world’s largest alliance for women’s, children’s and adolescents’ health. He joined there from the Global Fund to Fight AIDS, Tuberculosis and Malaria where he worked as Senior Policy Advisor in the Office of the Executive Director, leading the development of the 2017–2022 Global Fund Strategy.

Electric stimulation may be able to help blood vessels carry white blood cells and oxygen to wounds, speeding healing, a new study suggests.

The study, published in the Royal Society of Chemistry journal Lab on a Chip, found that steady generates increased permeability across vessels, providing new insight into the ways might grow.

The electrical stimulation provided a constant voltage with an accompanying electric current in the presence of fluid flow. The findings indicate that stimulation increases permeability of the blood vessel—an important characteristic that can help wound-healing substances in the blood reach injuries more efficiently.