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Biomedical gerontologist Aubrey de Grey, who’s Chief Science Officer of the SENS Research Foundation, is now predicting a 50% chance that people will begin retaining their youthful state via advanced science and technologies by the year 2036.

This is roughly around the same timeline that The Last Generation to Die is based on. Nailed it (hopefully)!

High-precision delivery of microrobots at the whole-body scale is of considerable importance for efforts toward targeted therapeutic intervention. However, vision-based control of microrobots, to deep and narrow spaces inside the body, remains a challenge. Here, we report a soft and resilient magnetic cell microrobot with high biocompatibility that can interface with the human body and adapt to the complex surroundings while navigating inside the body. We achieve time-efficient delivery of soft microrobots using an integrated platform called endoscopy-assisted magnetic actuation with dual imaging system (EMADIS).

Wiesendanger points out that unlike SARS and MERS, no intermediate host between bats and humans has been found more than a year since the start of the pandemic. Thus far, there is no evidence for the zoonotic theory to explain the outbreak.

Indeed, during the joint China-WHO report issued on Feb. 9, Liang Wannian, head of the Chinese National Health Commission’s Expert Panel of COVID-19 Response, stated that 50000 samples of wild animals from 300 different species (including bats) as well as 11000 farm animals in 31 Chinese provinces — taken between November 2019 and March 2020 — had all tested negative for SARS-CoV-2, the virus which causes COVID-19.

The researcher claimed that the SARS-CoV-2 virus is “astonishingly effective” at binding to human receptor cells (hACE2). He said this is due to its special hACE2 binding domains paired with the furin cleavage sites of the virus’ telltale spike protein.

He stated that this is the first time a coronavirus has exhibited both characteristics and that it points to a “non-natural origin.” Within the betacoronaviruses of sarbecovirus lineage B, the polybasic furin cleavage site is unique to SARS-CoV-2, according to News Medical Life Sciences.

Summary: A new technique which involves fusing human and chimpanzee skin cells that have been modified to act like stem cells, allowed researchers to identify two novel genetic differences between humans and chimps.

Source: Stanford University.

One of the best ways to study human evolution is by comparing us with nonhuman species that, evolutionarily speaking, are closely related to us. That closeness can help scientists narrow down precisely what makes us human, but that scope is so narrow it can also be extremely hard to define. To address this complication, researchers from Stanford University have developed a new technique for comparing genetic differences.

Tyson’s latest book “Cosmic Queries” covers the gamut from early Earth’s pond scum to potential multiverses to out-of-the-box ideas about the potential that we live in a false vacuum cosmos.


After the past year’s pandemic pall, it’s nice to be reminded that we remain inextricably connected to the cosmos beyond Earth’s atmosphere. In the new book “Cosmic Queries: StarTalk’s Guide to Who We Are, How We Got Here, and Where We’re Going,” astrophysicist and StarTalk podcast host Neil DeGrasse Tyson, along with George Mason University physics professor James Trefil, clearly remind us of our cosmic legacy.

Tyson, Director of New York City’s Hayden Planetarium at the American Museum of Natural History, is well known for his ability to provoke the public into thinking harder about our place in the cosmos. And “Cosmic Queries” does just that. Tyson and Trefil succinctly lead the reader through almost every aspect of cosmic history while addressing age-old questions with new verve.

Designed with a wealth of graphic and color images with pithy captions, the book is also peppered with amusing tweets from Tyson’s own Twitter account over the last decade. The book and his tweets touch on some of StarTalk’s recurring themes, such as Why is the universe the way it is? Are we alone? And how it all began and how it might all end?

“The research is part of an explosion of new techniques and ideas for studying early development. Today, in the same issue of Nature, two other research groups are reporting a leap forward in creating ”artificial” human embryos.

Those teams managed to coax ordinary skin cells and stem cells to self-assemble into look-alike early human embryos they call ”blastoids,” which they grew for about 10 days in the lab. Several kinds of artificial models of embryos have been described before, but those described today are among the most complete, because they possess the cells needed to form a placenta. That means they are a step closer to being viable human embryos that could develop further, even until birth.

Scientists say that they would never try to establish a pregnancy with artificial embryos—an act that would be forbidden today in most countries.


Researchers are growing embryos outside the body longer than has ever been possible.

Dr James Desmond, DVM, Co-Founder, Liberia Chimpanzee Rescue & Protection (LCRP), discussing his work at LCRP, as well as his zoonotic disease surveillance work with EcoHealth.


Liberia Chimpanzee Rescue & Protection (LCRP — https://www.liberiachimpanzeerescue.org/) is the first and only chimpanzee sanctuary and conservation center in Liberia rescuing chimpanzees who are victims of the illegal bush meat and pet trades. The organization has over 40 orphaned chimpanzees, nearly all under the age of five, currently under their care.

Dr. James Desmond is the co-founder Liberia Chimpanzee Rescue & Protection. He is a wildlife veterinarian and a consultant specializing in emerging disease and the illegal wildlife trade. He graduated from Tufts Cummings School of Veterinary Medicine, earning a Doctor of Veterinary Medicine degree and a Masters in Comparative Biomedical Sciences. Alongside his work with Liberia Chimpanzee Rescue & Protection, Dr. Desmond leads research on infectious disease, including identifying novel wildlife reservoirs for the Ebola virus.

Following in my recent series on subjects that are all the rage in anti-aging and longevity circles, to help you get a good grasp of the essentials so you can know what all the talk is about, and can make informed judgements rather than just following the herd blindly. This time it is on Metformin. This is a drug widely known as a diabetes drug and it has been in use for a very long time, indeed it is one of the most prescribed drugs there is. Recently it has also been a buzz word in the anti aging/longevity communities following the review of data and with it s mechanism of action, being touted and recommended by a variety of voices in the public domain. But how does it work, and how could it improve longevity? Is it safe? Well, if you want to go into a bit more depth and know all the details, I have put together a video which helps you understand what all the fuss is about. And whatever you are doing, have a great day.


Metformin is very popular in the anti aging paradigm currently so let’s have a look at what it is, what it offers, and what the trade offs are… because, well, it is always wise to have all the data.

In this video I will look at the history of metformin and describe its mechanism of action before delving into the current thoughts on its use as an anti aging supplement and longevity benefits due to its overall health benefits.