Scientists have managed to do something truly groundbreaking. According to a new paper published in Advanced Science, researchers have created programmable cyborg cells that could help revolutionize medicine and environmental cleanup efforts. The new research, which was carried out by researchers at the University of California, Davis, shows that it is possible to create semi-living cyborg cells that retain the capabilities of living cells, but are unable to divide and grow.
In 2023, the US healthcare industry is again facing several significant challenges, including ongoing high inflation rates, labor shortages, and the persistent impact of the COVID-19 pandemic. Despite continued difficulties, leaders in the space are working to find innovative solutions to improve the current system while looking ahead at the promising future of medicine that appears to have already arrived.
From artificial intelligence-based medicine to breakthroughs in precision neuroscience, we outline key trends expected to shape the healthcare landscape in 2023 and beyond.
The 2023 Trend Report: Impactful Healthcare Innovations to Watch.
๐๐๐จ๐ฉ๐ฅ๐ ๐๐ซ๐ ๐ณ๐๐ฉ๐ฉ๐ข๐ง๐ ๐ญ๐ก๐๐ข๐ซ ๐๐ซ๐๐ข๐ง๐ฌ ๐๐ญ ๐ก๐จ๐ฆ๐ ๐ญ๐จ ๐ข๐ฆ๐ฉ๐ซ๐จ๐ฏ๐ ๐๐จ๐๐ฎ๐ฌ ๐๐ง๐ ๐๐ฅ๐๐๐ซ ๐๐ซ๐๐ข๐ง ๐๐จ๐ . ๐๐ฎ๐ญ ๐ข๐ฌ ๐ข๐ญ ๐ฌ๐๐๐?
In 2021, Craig Gibbons was diagnosed with Lyme disease. His doctor prescribed him antibiotics, but the medication failed to eliminate one of his most debilitating symptoms: a lasting brain fog that made it difficult for him to focus or recall information.
So he went with a different approach: at-home brain stimulation.
Over the past few years, Gibbons had been experimenting with transcranial direct current stimulation, or tDCS, which delivers weak electrical currents to the brain through electrodes attached to the head.
Anna Wexler, an assistant professor of medical ethics and health policy at the University of Pennsylvania, studies why and how people use brain stimulation at home. Sheโs found that people are using the devices to treat mental health disorders or to improve mental performance.
โDepression and anxiety are the top two indications for people,โ Wexler said. โBut other reasons people used it for were for enhancement, so to improve focus, to improve memory, things like that.โ
Pre-event lecture for upcoming CNS Special Webinar.
Register now! https://www.cns.org/connectomics-webinar โ 7-9PM, 12 November, 2020 (CST)
Synthetic biology has made major strides towards the holy grail of fully programmable bio-micromachines capable of sensing and responding to defined stimuli regardless of their environmental context. A common type of bio-micromachines is created by genetically modifying living cells.[ 1 ] Living cells possess the unique advantage of being highly adaptable and versatile.[ 2 ] To date, living cells have been successfully repurposed for a wide variety of applications, including living therapeutics,[ 3 ] bioremediation,[ 4 ] and drug and gene delivery.[ 5, 6 ] However, the resulting synthetic living cells are challenging to control due to their continuous adaption and evolving cellular context. Application of these autonomously replicating organisms often requires tailored biocontainment strategies,[ 7-9 ] which can raise logistical hurdles and safety concerns.
In contrast, nonliving synthetic cells, notably artificial cells,[ 10, 11 ] can be created using synthetic materials, such as polymers or phospholipids. Meticulous engineering of materials enables defined partitioning of bioactive agents, and the resulting biomimetic systems possess advantages including predictable functions, tolerance to certain environmental stressors, and ease of engineering.[ 12, 13 ] Nonliving cell-mimetic systems have been employed to deliver anticancer drugs,[ 14 ] promote antitumor immune responses,[ 15 ] communicate with other cells,[ 16, 17 ] mimic immune cells,[ 18, 19 ] and perform photosynthesis.
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Messenger RNAs (mRNAs) contain chemical marks that are critical for antiviral defense in cells, according to a new study from researchers at Weill Cornell Medicine. The finding solves a 50-year mystery concerning the purpose of these chemical modifications, and suggests that faulty mRNA modification may underlie some autoimmune and inflammatory disorders.
๐๐๐๐๐ฅ ๐๐ฅ๐จ๐จ๐ ๐ฉ๐ซ๐๐ฌ๐ฌ๐ฎ๐ซ๐ ๐ฆ๐๐ฒ ๐ซ๐๐ฆ๐จ๐๐๐ฅ ๐๐ซ๐๐ข๐ง ๐๐ฅ๐๐๐ซ๐๐ง๐๐ ๐ฉ๐๐ญ๐ก๐ฐ๐๐ฒ๐ฌ ๐ฅ๐ข๐ง๐ค๐๐ ๐ญ๐จ ๐๐ซ๐๐ข๐ง ๐ก๐๐๐ฅ๐ญ๐ก, ๐๐๐ฆ๐๐ง๐ญ๐ข๐
๐พ๐ก๐ค๐จ๐ ๐ง๐๐ซ๐๐๐ฌ ๐ค๐ ๐๐๐ ๐จ๐๐๐ฃ๐จ ๐๐ค๐ช๐ฃ๐ ๐ข๐ค๐ง๐ ๐๐ฃ๐ฉ๐๐ฃ๐จ๐๐ซ๐ ๐๐๐๐ ๐๐ก๐ค๐ค๐ ๐ฅ๐ง๐๐จ๐จ๐ช๐ง๐ ๐ฉ๐ง๐๐๐ฉ๐ข๐๐ฃ๐ฉ (๐ฉ๐๐ง๐๐๐ฉ๐๐ ๐ฉ๐ค ๐๐๐๐๐๐ซ๐ ๐ ๐จ๐ฎ๐จ๐ฉ๐ค๐ก๐๐ ๐ฅ๐ง๐๐จ๐จ๐ช๐ง๐ ๐ก๐๐จ๐จ ๐ฉ๐๐๐ฃ 120 ๐ข๐ข ๐๐) ๐ฌ๐๐จ ๐ข๐ค๐ง๐ ๐๐๐๐๐๐ฉ๐๐ซ๐ ๐ฉ๐๐๐ฃ ๐ ๐ก๐๐จ๐จ-๐๐ฃ๐ฉ๐๐ฃ๐จ๐ ๐ฉ๐ง๐๐๐ฉ๐ข๐๐ฃ๐ฉ ๐๐ค๐๐ก ๐ค๐ 140 ๐ข๐ข ๐๐ ๐จ๐ฎ๐จ๐ฉ๐ค๐ก๐๐ ๐๐ฃ ๐๐๐๐๐๐ซ๐๐ฃ๐ ๐ ๐ฅ๐ค๐จ๐๐ฉ๐๐ซ๐ ๐จ๐ฉ๐ง๐ช๐๐ฉ๐ช๐ง๐๐ก ๐๐๐๐ฃ๐๐ ๐๐ฃ ๐ฉ๐๐ ๐๐ง๐๐๐ฃโ๐จ ๐ฅ๐๐ง๐๐ซ๐๐จ๐๐ช๐ก๐๐ง ๐จ๐ฅ๐๐๐๐จ: ๐ฅ๐๐ฉ๐๐ฌ๐๐ฎ๐จ ๐ฉ๐๐๐ฉ ๐๐ง๐ ๐๐ข๐ฅ๐ค๐ง๐ฉ๐๐ฃ๐ฉ ๐ฉ๐ค ๐๐ก๐๐๐ง๐๐ฃ๐ ๐ฉ๐ค๐ญ๐๐ฃ๐จ ๐๐ฃ๐ ๐ค๐ฉ๐๐๐ง ๐๐ฎ๐ฅ๐ง๐ค๐๐ช๐๐ฉ๐จ.
๐๐ ๐ฉ๐๐ ๐๐ง๐๐๐ฃ ๐๐๐ฃ๐ฃ๐ค๐ฉ ๐ฅ๐ง๐ค๐ฅ๐๐ง๐ก๐ฎ ๐๐ก๐๐๐ง ๐ข๐๐ฉ๐๐๐ค๐ก๐๐ ๐๐ฎ๐ฅ๐ง๐ค๐๐ช๐๐ฉ๐จ, ๐ฉ๐๐๐ฎ ๐๐๐๐ช๐ข๐ช๐ก๐๐ฉ๐ ๐๐ฃ๐ ๐ข๐๐ฎ ๐๐ค๐ฃ๐ฉ๐ง๐๐๐ช๐ฉ๐ ๐ฉ๐ค ๐ฉ๐๐ ๐๐๐ซ๐๐ก๐ค๐ฅ๐ข๐๐ฃ๐ฉ ๐ค๐ ๐๐๐ข๐๐ฃ๐ฉ๐๐, ๐ง๐๐จ๐๐๐ง๐๐๐๐ง๐จ ๐จ๐๐๐.
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(NewMediaWire) โ February 2, 2023 โ DALLAS Among people who received more intensive treatment for high blood pressure, evaluations of MRI scans indicated a positive change in brain structures involved in its ability to clear toxins and other byproducts, according to preliminary research to be presented at the American Stroke Associationโs International Stroke Conference 2023. The meeting, held in person in Dallas and virtually, Feb. 8โ10, 2023, is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health.
The study is the first to examine whether intensive blood pressure treatment may slow, or reverse structural changes related to the volume of the brainโs perivascular spaces, areas of the brain around the blood vessels that are involved in the clearance of toxins and other byproducts. These areas tend to enlarge as people get older or have more cardiovascular risk factors.
PROVIDENCE, R.I. [Brown University] โ More than two decades ago, a team of Brown University researchers set out with an ambitious goal to provide people with paralysis a revolutionary neurotechnology capable of turning thoughts about movement into actual action, using a tiny device that would one day be implanted in the surface of the brain. Their work led to an ongoing, multi-institution effort to create the BrainGate brain-computer interface, designed to allow clinical trial participants with paralysis to control assistive devices like computers or robotic limbs just by thinking about the action they want to initiate.
Open Access Paper:
https://n.neurology.org/content/early/2023/01/13/WNL.
In an important step toward a medical technology that could help restore independence of people with paralysis, researchers find the investigational BrainGate neural interface system has low rates of associated adverse events.
Working with hundreds of thousands of high-resolution images, researchers from the Allen Institute for Cell Science, a division of the Allen Institute, put numbers on the internal organization of human cells โ a biological concept that has proven incredibly difficult to quantify until now.
The scientists also documented the diverse cell shapes of genetically identical cells grown under similar conditions in their work. Their findings were recently published in the journal Nature.
โThe way cells are organized tells us something about their behavior and identity,โ said Susanne Rafelski, Ph.D., Deputy Director of the Allen Institute for Cell Science, who led the study along with Senior Scientist Matheus Viana, Ph.D. โWhatโs been missing from the field, as we all try to understand how cells change in health and disease, is a rigorous way to deal with this kind of organization. We havenโt yet tapped into that information.โ