A playlist of Freethink’s most popular videos about drugs to improve well-being.
Drugs to Improve Well-Being
Posted in biotech/medical
Category: biotech/medical – Page 1,208
During that uncomfortable period between puberty and adulthood, the brain undergoes carefully orchestrated changes in gene expression and epigenetic modification. Alcohol, unfortunately, interferes with this biological architecture. Consequently, mistakes are made, and gene expression and modification do not go as planned, leaving the person vulnerable to a lifetime of psychiatric challenges, such as anxiety and alcoholism.
A team of researchers from the University of Illinois Chicago recently found they could reverse these changes in rats via gene editing. If their findings carry through to human studies, gene editing may be a potential treatment for anxiety and alcohol-use disorder in adults who were exposed to binge drinking in their adolescence.
The relentless evolution of the coronavirus, which has spawned new variants to fuel fresh surges of disease every four to six months, could in the not-distant future propel the virus to overtake measles as the most contagious of all known infections.
Increasing infectiousness does not necessarily make the virus deadlier, but it could make it harder to control, and leave communities vulnerable to the repeated waves of illness that have defined the pandemic.
The variants now dominating around the world may be five to 10 times more infectious than the original virus that sparked the pandemic in China in late 2019, health experts believe. Lately each variant has outpaced its parent — omicron, with its massive evolutionary jump, was about three times more infectious than delta. Its subvariants — BA.2 and BA.2.12.1, which are driving the latest surge in the Bay Area — are each more infectious still, by 20% to 30%.
Summary: Researchers used optogenetics techniques to stimulate specific brain areas to increase neurogenesis and the production of neural stem cells to improve memory, cognition, and emotional processing in animal models.
Source: UNC Health Care.
We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer’s and Parkinson’s, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience. One way to push back against cognitive decline and anxiety would be to spur the creation of new neurons.
The long term goal for Elon Musk and brain to computer interfaces (brain chips) is to merge our minds with artificial intelligence. While the short term goal for Neuralink and other companies is to help people with medical issues.
This short documentary video takes a look at connecting our brains to computers, and how this works is explained. We also take a look at the downsides of people connecting their brains, the technology being used today, and Elon Musk’s thoughts.
Other topics in the video include:
• How in the future we could download and upload our memories and dreams so they are not forgotten.
• The different types of brain to computer implants and devices.
• Updates (demonstrating and testing on pigs, and soon humans) and a summery of where we are today with this technology.
• Tutorial on how it works.
• And what other sci-fi like things will brains connected to computers allow us humans to do.
An experiment in mice has shown that a protein in the nervous system can have a rejuvenating effect on older animals, a finding which may help with future research into how to treat the neurological disease.
Massachusetts health officials on Wednesday confirmed a single case of monkeypox virus infection in an adult male who health officials said recently traveled to Canada.
The Department of Public Health said monkeypox is a rare but potentially serious viral illness that typically begins with flu-like symptoms and swelling of the lymph nodes. It progresses to a rash on the face and body, with most infections lasting two to four weeks.
True stories of indefatigable researchers, heroic engineers, and champions of, neuroscience who are finally turning the corner in the effort to understand, heal, and improve the human brain.
Al has a hard time walking up the stairs to his home’s second floor these days, so he lives on the first. In a lounge chair, surrounded by pictures of his family and the homes he built, he slowly, carefully crosses one knee at the ankle like he’s in a business meeting. His legs are thin and pale and papery. His face, too, has taken on a gauntness since the photo of his daughter’s wedding, mounted on the wall right in front of him, was taken back in 2009. Al lunges forward as if he might stand. But then, when he tries to say hello, all that comes out is a guttural moan. When Al, who is sixty-eight, was diagnosed with progressive supranuclear palsy (PSP) in 2012, he was not guaranteed even this. The disease, caused by degeneration of cells in areas of the brain associated with movement, balance, and thinking, often results in death in about seven years. It has no known cause and no cure.
In a few months, a daring clinical trial may fundamentally lower heart attack risk in the most vulnerable people. If all goes well, it will just take one shot.
It’s no ordinary shot. The trial, led by Verve Therapeutics, a biotechnology company based in Massachusetts, will be one of the first to test genetic base editors directly inside the human body. A variant of the gene editing tool CRISPR-Cas9, base editors soared to stardom when first introduced for their efficiency at replacing single genetic letters without breaking delicate DNA strands. Because it’s safer than the classic version of CRISPR, the new tool ignited hope that it could be used for treating genetic diseases.
Verve’s CEO, Dr. Sekar Kathiresan, took note. A cardiologist at Harvard University, Kathiresan wondered if base editing could help solve one of the main killers of our time: heart attacks. It seemed the perfect test case. We know one major cause of heart attacks—high cholesterol levels, particularly a version called LDL-C (Low-density lipoprotein cholesterol). We also know several major genes that control its level. And—most importantly—we know the DNA letter swap that can, in theory, drastically lower LDL-C and in turn throttle the risk of heart attacks.
Len RosenFalcon 9 has been a spectacular success for SpaceX. The purpose of the Falcon Heavy is likely to be superseded by Starship which likely means the Heavy will be discontinued sooner than later.
Eric KlienAuthor.
Len Rosen Actually, Starship will rapidly grab all of the Falcon 9 payloads, except for humans which will be much slower to transition. In fact, it looks like the first orbital Starship launch will try to launch some Starlink satellites.
View 1 more reply.
Len Rosen shared a link.
No one should think we are over COVID.