Feb 4, 2023

Exploring the Inner Workings of Human Cells — Database of 200,000 Cell Images Yields New Mathematical Framework

Posted by in categories: biotech/medical, genetics, health, mathematics

Working with hundreds of thousands of high-resolution images, researchers from the Allen Institute for Cell Science, a division of the Allen Institute, put numbers on the internal organization of human cells — a biological concept that has proven incredibly difficult to quantify until now.

The scientists also documented the diverse cell shapes of genetically identical cells grown under similar conditions in their work. Their findings were recently published in the journal Nature.

“The way cells are organized tells us something about their behavior and identity,” said Susanne Rafelski, Ph.D., Deputy Director of the Allen Institute for Cell Science, who led the study along with Senior Scientist Matheus Viana, Ph.D. “What’s been missing from the field, as we all try to understand how cells change in health and disease, is a rigorous way to deal with this kind of organization. We haven’t yet tapped into that information.”

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