A nanoscale rotary motor made of DNA origami, driven by ratcheting and powered by an external electric field, shows the ability to wind up a spring and has mechanical capabilities approaching those of biological motors.
Category: biotech/medical – Page 1,179
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons—the cells that enable sensations like touch, pain and itch.
The study, conducted using embryonic stem cells from mice, also identified a method for producing all types of sensory interneurons in the laboratory. 𝐈𝐟 𝐭𝐡𝐢𝐬 𝐰𝐨𝐫𝐤 𝐜𝐚𝐧 𝐛𝐞 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐞𝐝 𝐮𝐬𝐢𝐧𝐠 𝐡𝐮𝐦𝐚𝐧 𝐬𝐭𝐞𝐦 𝐜𝐞𝐥𝐥𝐬, 𝐭𝐡𝐞 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐬𝐚𝐢𝐝, 𝐢𝐭 𝐜𝐨𝐮𝐥𝐝 𝐛𝐞 𝐚 𝐤𝐞𝐲 𝐬𝐭𝐞𝐩 𝐭𝐨𝐰𝐚𝐫𝐝 𝐭𝐡𝐞 𝐝𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭 𝐨𝐟 𝐬𝐭𝐞𝐦 𝐜𝐞𝐥𝐥-𝐛𝐚𝐬𝐞𝐝 𝐭𝐡𝐞𝐫𝐚𝐩𝐢𝐞𝐬 𝐭𝐡𝐚𝐭 𝐫𝐞𝐬𝐭𝐨𝐫𝐞 𝐬𝐞𝐧𝐬𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐩𝐞𝐨𝐩𝐥𝐞 𝐰𝐡𝐨 𝐡𝐚𝐯𝐞 𝐥𝐨𝐬𝐭 𝐟𝐞𝐞𝐥𝐢𝐧𝐠 𝐢𝐧 𝐩𝐚𝐫𝐭𝐬 𝐨𝐟 𝐭𝐡𝐞𝐢𝐫 𝐛𝐨𝐝𝐲 𝐝𝐮𝐞 𝐭𝐨 𝐬𝐩𝐢𝐧𝐚𝐥 𝐜𝐨𝐫𝐝 𝐢𝐧𝐣𝐮𝐫𝐢𝐞𝐬.
Ageless biomarkers and diagnostics company overview.
So proud of fellow Ageless Partners® coach Kamila Issabayeva for giving such an excellent overview of all the different Biomarkers currently on the market. Also, I had the pleasure of being a co-moderator together with Jason C. Mercurio of this wonderful intellectual presentation.
She talks about the ideal Aging biomarker panel, pricing, accuracy and which tests have the highest correlation Aging.
A highly informative presentation that you would not want to miss!
#Biomarkers #Aging #Longevity #Lifespan
It’s all about a mutation of genome. Researchers from the University of California San Diego School of Medicine have discovered a set of human gene mutations that prevent cognitive decline and dementia in older adults, according to a new study published on July 9, 2022, in the journal Molecular Biology and Evolution. The scientists focused on one of the mutated genes and traced its evolution through its appearance in the human genome.
Interesting Engineering is a cutting edge, leading community designed for all lovers of engineering, technology and science.
Circa 2021
Vaccines are made in batches, but some researchers want to overhaul that system to make the manufacturing continuous, efficient, and democratic.
😳!!!!!
In a milestone that could turn sci-fi into fact, the first U.S. clinical trial of a brain implant that returns the power of communication to severely paralyzed people has begun. | In a milestone that could turn sci-fi into fact, the first U.S. clinical trial of a brain implant that returns the power…
Brain-computer interfaces have become a practical (if limited) reality in the US. Synchron says it has become the first in the country to implant a BCI in a human patient. Doctors in New York’s Mount Sinai West implanted the company’s Stentrode in the motor cortex of a participant in Synchron’s COMMAND trial, which aims to gauge the usefulness and safety of BCIs for providing hands-free device control to people with severe paralysis. Ideally, technology like Stentrode will offer independence to people who want to email, text and otherwise handle digital tasks that others take for granted.
Surgeons installed the implant using an endovascular procedure that avoids the intrusiveness of open-brain surgery by going through the jugular vein. The operation went “extremely well” and let the patient return home 48 hours later, according to Synchron. An ongoing Australian trial has also proven successful so far, with four patients still safe a year after receiving their implants.
It may take a long time before doctors can offer Synchron’s BCIs to patients. The company received FDA approval for human trials in July 2021, and it’s still expanding the COMMAND trial as of this writing. Still, the US procedure represents a significant step toward greater autonomy for people with paralysis. It also represents a competitive victory — Elon Musk’s Neuralink has yet to receive FDA permission for its own implant.
Summary: Researchers have created a new blueprint that outlines how embryonic stem cells from mice become sensory interneurons and identified a method for producing sensory interneurons in a lab setting. If the results can be replicated in human stem cells, researchers say the findings could contribute to the development of therapies to restore sensation to those suffering nerve damage and spinal cord injury.
Source: UCLA
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons — the cells that enable sensations like touch, pain and itch.
Genomes contain regions between protein-coding genes that produce lengthy RNA molecules that never give rise to a protein. These long intergenic non-coding RNAs (lincRNAs) are thought to have important functions, such as regulating responses to environmental change. However, a paucity of well-annotated lincRNA data, especially for crop plants, has precluded a deeper understanding of their roles.
Up until now, there have been no systematic genome-wide studies that both confirmed DNA sequences that produce lincRNAs and proposed functions for those lincRNAs. Plus, data are reported differently across studies, making direct comparisons among them difficult.
These barriers inspired researchers at the Boyce Thompson Institute to take a comprehensive look at the identity, production and function of lincRNAs in four species in the mustard family, including the model organism Arabidopsis thaliana, and Brassica rapa, a species that produces boy choy, turnips and other food crops.