Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1,182

Scientists have demonstrated that a brain-penetrating candidate drug currently in development as a cancer therapy can promote regeneration of damaged nerves after spinal trauma.

The research used cell and animal models to show that when taken orally the candidate drug, known as AZD1390, can block the response to DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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Researchers from Oxford Nanopore Technologies, Weill Cornell Medicine, and the New York Genome Center have created a new technique to evaluate the three-dimensional structure of the human DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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Medical microrobots could aid doctors in providing better illness prevention and treatment. However, the majority of these gadgets are created from synthetic materials that incite in vivo immunological reactions.

Scientists have now successfully utilized lasers to precisely manipulate neutrophils, a type of white blood cell, in living fish as a natural, biocompatible microrobot for the first time, as reported in ACS Central Science.

Microrobots that are now being developed for medical use need to be injected into an animal or ingested as capsules. However, scientists have discovered that these tiny items frequently cause immunological reactions in small animals, which prevents the elimination of microrobots from the body before they can carry out their functions.

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Summary: Study reveals how motor memories are formed and how they remain persistent. The findings may help illuminate the root cause of motor disorders like Parkinson’s disease.

Source: Stanford.

Why is it that someone who hasn’t ridden a bicycle in decades can likely jump on and ride away without a wobble, but could probably not recall more than a name or two from their 3rd grade class?

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Up until recently, almost all pediatric liver cancers were classified as either hepatoblastoma or hepatocellular carcinoma. However, pediatric pathologists have noted that certain liver tumors have histological characteristics that do not readily match either of these two carcinoma models. The outcomes for patients with these tumors are poor and the tumors are less likely to respond to chemotherapy.

Dr. Pavel Sumazin, an associate professor of pediatrics at Texas Children’s Cancer and Hematology Center and Baylor College of Medicine, sought to better understand this high-risk cancer.

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