Biotech/medical – Lifeboat News: The Blog

New FDA warning links cough medicine to rise in child poisonings

Posted by Genevieve Klien in biotech/medical

Nov 16
2022

Parents and medical providers are being called on to be careful with prescription cough medication as overdoses among children are on the rise.

Calls to poison control centers in the United States reporting the ingestion of prescription cough medicine by children rose by 158% between 2010 and 2018, according to a study published Tuesday by the Food and Drug Administration.

The study, published in the journal Pediatrics, found that pediatric poisonings involving the drug benzonatate, sold under the brand name Tessalon, have increased each year.

Read more | >

Empathy Estimated Using Single-Cell Recordings in Human Brain

Posted by Nicholi Avery in biotech/medical, neuroscience

Nov 16
2022

Can we measure empathy?

𝐄𝐦𝐩𝐚𝐭𝐡𝐲 𝐄𝐬𝐭𝐢𝐦𝐚𝐭𝐞𝐝 𝐔𝐬𝐢𝐧𝐠 𝐒𝐢𝐧𝐠𝐥𝐞-𝐂𝐞𝐥𝐥 𝐑𝐞𝐜𝐨𝐫𝐝𝐢𝐧𝐠𝐬 𝐢𝐧 𝐇𝐮𝐦𝐚𝐧 𝐁𝐫𝐚𝐢𝐧

𝘼 𝙨𝙩𝙪𝙙𝙮 𝙞𝙣 𝙚𝙇𝙞𝙛𝙚 𝙖𝙣𝙖𝙡𝙮𝙯𝙚𝙙 𝙩𝙝𝙚 𝙘𝙤𝙣𝙩𝙧𝙞𝙗𝙪𝙩𝙞𝙤𝙣 𝙤𝙛 𝙩𝙝𝙚 𝙞𝙣𝙨𝙪𝙡𝙖 𝙞𝙣 𝙤𝙪𝙧 𝙖𝙗𝙞𝙡𝙞𝙩𝙮 𝙩𝙤 𝙪𝙣𝙙𝙚𝙧𝙨𝙩𝙖𝙣𝙙 𝙩𝙝𝙚 𝙥𝙖𝙞𝙣 𝙤𝙛 𝙤𝙩𝙝𝙚𝙧𝙨 𝙗𝙮 𝙧𝙚𝙘𝙤𝙧𝙙𝙞𝙣𝙜 𝙛𝙧𝙤𝙢 𝙚𝙡𝙚𝙘𝙩𝙧𝙤𝙙𝙚𝙨 𝙚𝙢𝙗𝙚𝙙𝙙𝙚𝙙 𝙞𝙣 𝙩𝙝𝙚 𝙝𝙪𝙢𝙖𝙣 𝙗𝙧𝙖𝙞𝙣 𝙩𝙝𝙖𝙩 𝙢𝙚𝙖𝙨𝙪𝙧𝙚𝙙 𝙣𝙚𝙪𝙧𝙤𝙣𝙖𝙡 𝙖𝙘𝙩𝙞𝙫𝙞𝙩𝙮 𝙞𝙣 𝙞𝙣𝙙𝙞𝙫𝙞𝙙𝙪𝙖𝙡 𝙘𝙚𝙡𝙡𝙨 𝙞𝙣 𝙚𝙥𝙞𝙡𝙚𝙥𝙨𝙮 𝙥𝙖𝙩𝙞𝙚𝙣𝙩𝙨 𝙖𝙨 𝙩𝙝𝙚𝙮 𝙫𝙞𝙚𝙬𝙚𝙙 𝙨𝙝𝙤𝙧𝙩 𝙢𝙤𝙫𝙞𝙚𝙨 𝙤𝙛 𝙖𝙣 𝙖𝙘𝙩𝙧𝙚𝙨𝙨 𝙞𝙣 𝙥𝙖𝙞𝙣. 𝙏𝙝𝙚 𝙨𝙩𝙪𝙙𝙮 𝙞𝙢𝙥𝙧𝙤𝙫𝙚𝙨 𝙤𝙪𝙧 𝙪𝙣𝙙𝙚𝙧𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙤𝙛 𝙩𝙝𝙚 𝙞𝙣𝙝𝙚𝙧𝙚𝙣𝙩 𝙙𝙞𝙛𝙛𝙚𝙧𝙚𝙣𝙘𝙚𝙨 𝙞𝙣 𝙥𝙚𝙤𝙥𝙡𝙚’𝙨 𝙖𝙗𝙞𝙡𝙞𝙩𝙮 𝙩𝙤 𝙚𝙢𝙥𝙖𝙩𝙝𝙞𝙯𝙚 𝙖𝙣𝙙 𝙧𝙚𝙖𝙘𝙩 𝙩𝙤 𝙩𝙝𝙚 𝙥𝙖𝙞𝙣 𝙤𝙛 𝙤𝙩𝙝𝙚𝙧𝙨, 𝙖𝙨 𝙬𝙚𝙡𝙡 𝙖𝙨 𝙥𝙤𝙩𝙚𝙣𝙩𝙞𝙖𝙡 𝙢𝙚𝙘𝙝𝙖𝙣𝙞𝙨𝙢𝙨 𝙛𝙤𝙧 𝙩𝙝𝙚 𝙡𝙖𝙘𝙠 𝙤𝙛 𝙚𝙢𝙥𝙖𝙩𝙝𝙮 𝙞𝙣 𝙘𝙚𝙧𝙩𝙖𝙞𝙣 𝙣𝙚𝙪𝙧𝙤𝙥𝙨𝙮𝙘𝙝𝙞𝙖𝙩𝙧𝙞𝙘 𝙘𝙤𝙣𝙙𝙞𝙩𝙞𝙤𝙣𝙨.

Using intracranial electroencephalographic (iEEG) recordings and single-cell recordings from the human insulae in patients with epilepsy who have electrodes embedded in their brains, scientists have analyzed the contribution of the insula in our ability to understand the pain of others. The study improves our understanding of the inherent differences in people’s ability to empathize and react to the pain of others, as well as potential mechanisms for the lack of empathy in certain neuropsychiatric conditions.

Read more | >

Potential Interventions For HUMAN LONGEVITY, CaAKG Is More Effective for People w/Accelerating Aging

Posted by Montie Adkins in biotech/medical, chemistry, genetics, life extension

Nov 16
2022

This is primarily about Rejuvant or AKG trials. When they first reported an 8 year age difference I did not truly believe it as that would mean I could take it, de-age, then age a bit, then just take it again. The tests however are ongoing and will feature people who are biologically older than their calendar age. There is also mention of 110 drugs/supplements that do “something” to mice. That would be quite a stack to take.

Dr Brian Kennedy presents potential interventions for extend our healthspan. Among them, Rejuvant – a CaAKG supplement which contain calcium + alpha-ketoglutarate shows better response for people who has biological age older than chronological age.

The first human trial of Rejuvant to reverse human biological age by 8 years in 7 month.

Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660611/

Dr. Brian Kennedy is internationally recognized for his research in the basic biology of aging and as a visionary committed to translating research discoveries into new ways of delaying, detecting, and preventing human aging and associated diseases. He is a Professor in the Departments of Biochemistry and Physiology at National University Singapore and Director of the Centre for Healthy Ageing in the National University Health System. From 2010 to 2016 he was the President and CEO of the Buck Institute for Research on Aging. Currently, he remains as a Professor at the Institute. Dr. Kennedy also has an adjunct appointment at the USC Davis School of Gerontology. Dr. Kennedy is also actively involved Biotechnology companies, serving in consulting and Board capacities, as well as Scientific Director of Affirmativ Health. Dr. Kennedy also serves as a Co-Editor-In-Chief at Aging Cell.

Continue reading “Potential Interventions For HUMAN LONGEVITY, CaAKG Is More Effective for People w/Accelerating Aging” | >

Life really CAN flash before your eyes when you’re dying!

Posted by Jose Ruben Rodriguez Fuentes in biotech/medical, health

Nov 16
2022

This included ‘evaluating life’, such as seeing memories and assessing how they had treated others during their time alive.

Others felt like they were ‘heading to a destination’ or were even aware that CPR was being performed.

Dr Sam Parnia, study author and a critical care expert from New York medical centre NYU Langone Health, said patients can also be aware of activities in intensive care after CPR and hear medics treating them.

Read more | >

Nerve Cell Discovery May Lead to Better Treatment for Diseases of the Nervous System

Posted by Genevieve Klien in biotech/medical, neuroscience

Nov 16
2022

Summary: Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer’s.

Source: University of Bath.

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King’s College London and the University of Bath in the UK.

Read more | >

This 4 oz size is for those suffering from chronic conditions

Posted by Paul Battista in biotech/medical

Nov 16
2022

We have had extremely positive results from customers who were suffering from Cancer, Heart Disease, High Blood Pressure, High Cholesterol, Thyroid Issues, Arthritis, Fibromyalgia, auto-immune diseases, Crohn’s Disease, Type 2 Diabetes, heavy metal toxicity, viral infections, scar tissue, and more.

Ingredients: Extract of Wild Harvested Shiaqga mushroom, Organic Black Cumin Seed Oil, Sacred Frankincense Oil, Organic Lemon Essential Oil, Organic Cinnamon Bark Essential Oil, and Organic Peppermint Essential Oil

The Rapid Immune Recovery has a 20x stronger concentration of the Shiaqga mushroom than the Daily Immune Restoration and 10X More Sacred Frankincense than Daily Immune Restoration Each bottle is a 30 day supply at 4 ml per day.

Read more | >

Researchers develop new, heat-efficient nanoparticles for treating cancer

Posted by Kelvin Dafiaghor in biotech/medical, nanotechnology

Nov 16
2022

Oregon State University scientists have invented a way to make magnetic nanoparticles that get hotter than any previous nanoparticle, improving their cancer fighting ability.

Faculty from the OSU College of Pharmacy spearheaded a collaboration that developed an advanced thermal decomposition method for producing nanoparticles able to reach temperatures in cancer lesions of up to 50 degrees Celsius, or 122 degrees Fahrenheit, when exposed to an alternating magnetic field.

Findings of the preclinical study led by Oleh Taratula and Olena Taratula were published today in the journal Small Methods.

Read more | >

MIT solved a century-old differential equation to break ‘liquid’ AI’s computational bottleneck

Posted by Dan Kummer in biotech/medical, information science, mathematics, robotics/AI

Nov 16
2022

Last year, MIT developed an AI/ML algorithm capable of learning and adapting to new information while on the job, not just during its initial training phase. These “liquid” neural networks (in the Bruce Lee sense) literally play 4D chess — their models requiring time-series data to operate — which makes them ideal for use in time-sensitive tasks like pacemaker monitoring, weather forecasting, investment forecasting, or autonomous vehicle navigation. But, the problem is that data throughput has become a bottleneck, and scaling these systems has become prohibitively expensive, computationally speaking.

On Tuesday, MIT researchers announced that they have devised a solution to that restriction, not by widening the data pipeline but by solving a differential equation that has stumped mathematicians since 1907. Specifically, the team solved, “the differential equation behind the interaction of two neurons through synapses… to unlock a new type of fast and efficient artificial intelligence algorithms.”

“The new machine learning models we call ‘CfC’s’ [closed-form Continuous-time] replace the differential equation defining the computation of the neuron with a closed form approximation, preserving the beautiful properties of liquid networks without the need for numerical integration,” MIT professor and CSAIL Director Daniela Rus said in a Tuesday press statement. “CfC models are causal, compact, explainable, and efficient to train and predict. They open the way to trustworthy machine learning for safety-critical applications.”

Read more | >

Two Fathers One Egg

Posted by Kelvin Dafiaghor in biotech/medical, sex

Nov 16
2022

What will it take for a same-sex couple—two males or two females—to be able to produce a biological child by combining their genomes in the same way that male-female couples do? Just to be clear, we’re not talking about adopting. Nor do we mean one mate fertilizes a donor egg or is fertilized with donated sperm. Those things have long existed. We mean you take two women or two men and make a baby.

And they’ve already done it with two male mice.

Read more | >

Transforming bacterial cells into living artificial neural circuits

Posted by Dan Breeden in bioengineering, biotech/medical, genetics, robotics/AI

Nov 15
2022

Bringing together concepts from electrical engineering and bioengineering tools, Technion and MIT scientists collaborated to produce cells engineered to compute sophisticated functions— biocomputers of sorts.

Graduate students and researchers from Technion—Israel Institute of Technology Professor Ramez Daniel’s Laboratory for Synthetic Biology & Bioelectronics worked together with Professor Ron Weiss from the Massachusetts Institute of Technology to create genetic “devices” designed to perform computations like artificial neural circuits. Their results were recently published in Nature Communications.

The genetic material was inserted into the bacterial cell in the form of a plasmid: a relatively short DNA molecule that remains separate from the bacteria’s “natural” genome. Plasmids also exist in nature, and serve various functions. The research group designed the plasmid’s genetic sequence to function as a simple computer, or more specifically, a simple artificial neural network. This was done by means of several genes on the plasmid regulating each other’s activation and deactivation according to outside stimuli.

Read more | >