Lifeboat Foundation: Safeguarding Humanity
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Category: bioengineering – Page 214

For the first time ever, scientists were able to successfully cut out the HIV genes from live animals, and they had over a 50% success rate.

A significant milestone was achieved today in the fight against HIV—scientists led by Kamel Khalili of the Comprehensive NeuroAIDS Center at Temple University just reported that, for the first time, HIV genes have been successfully eliminated from the genomes of animals infected with the virus.

“In a proof-of-concept study, we show that our gene editing technology can be effectively delivered to many organs of two small animal models and excise large fragments of viral DNA from the host cell genome,” explained Khalili.

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Fox 29 — Good Day Philadelphia

http://www.fox29.com/140735577-video

Reanimalogo

NBC TV 10

http://www.nbcphiladelphia.com/news/local/Zombies-from-Phill…65101.html

fmri5

CNN en Espanol

http://cnnespanol.cnn.com/video/cnnee-encuentro-intvw-joel-o…-cerebral/

Researcher-test

A hybrid hydrostatic transmission and human-safe haptic telepresence robot (credit: Disney Research)

A human-safe lifelike telepresence robot with the delicacy and precision needed to pick up an egg without breaking it or thread a sewing needle has been developed by researchers at Disney Research, the Catholic University of America, and Carnegie Mellon University.

The secret: a hydrostatic transmission that precisely drives robot arms, offering extreme precision with almost no friction or play.

The hybrid transmission design also makes it possible to halve the number of bulky hydraulic lines that a fully hydraulic system would require and allows for making its robotic limbs lighter and smaller, said John P. Whitney, an assistant professor of mechanical and industrial engineering at Northeastern University, who led the development of the transmission while an associate research scientist at Disney Research.

Continue reading “A robot with human-like grace and precision” | >

KITCHENER — Big jumps in life expectancy will begin in as little as 10 years thanks to advances in nanotechnology and 3D printing that will also enable wireless connections among human brains and cloud computers, a leading futurist said Thursday.

“In 10 or 15 years from now we will be adding more than a year, every year, to your life expectancy,” Ray Kurzweil told an audience of 800 people at Communtech’s annual Tech Leadership conference.

Kurzweil, a futurist, inventor and author, as well as a director of engineering at Google, calls this “radical life extension.”

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Hope for HIV patients.

In 2014, a team of researchers in the Lewis Katz School of Medicine at Temple University became the first to successfully eliminate the HIV-1 virus from cultured human cells. Fewer than two years later, the team has made further strides in its research by eliminating the virus from the genome of human T-cells using the specialized gene editing system they designed.

In a new study published in Scientific Reports, the researchers show that the method can both effectively and safely eliminate the virus from the DNA of human cells grown in culture.

How this research differs In previous work, the team—led by Kamel Khalili, professor and chair of the Department of Neuroscience at Temple—had demonstrated the ability of their technology to snip out HIV-1 DNA from normal human cells. The newest findings used that same technology to snip out the virus from latently and productively infected CD4+ T-cells, which host the virus in persons infected with HIV.

Continue reading “Scientists prove effectiveness of gene editing system in eliminating HIV from DNA of CD4+ T-cells” | >

Next time you go for a brain scan; you could actually see dissolvable electrodes.

Hmmm

Scientists at the University of Pennsylvania in a study funded by the Defense Advance Research Projects Agency (DARPA) are developing implantable electrodes for brain monitoring that melt away at a predetermined rate. The devices could come in handy for monitoring and treating certain neurophysiological disorders such as Parkinson’s, depression and chronic pain.

The electrodes, which are made from layers of silicon and a chemical element, molybdenum, dissolve at a known rate according to thickness. The devices can provide “continuous streams of data for guiding medical care over predetermined periods of time,” Brian Litt, senior co-author on the study and a professor of neurology, neurosurgery and bioengineering at UPenn, said in a statement.

Continue reading “DARPA-backed researchers create dissolvable electrodes for brain monitoring” | >

Samsung get into the cancer treatment space with their own Q-Dot technology? Another reason for the FDA to show up in tech’s backyard; lookout for all those future federal and state regs & compliance training that will be coming that eats up 20 hours each month of your scientists and engineering talent’s time.

For a lot of users, Samsung might be known best for their smartphones and other mobile devices, but the company is so much more than that. Many of you reading this might have one of Samsung’s Super HD TV sets, a curved Samsung TV or some other model of theirs. Next to smartphones one of their more popular consumer electronics is of course of TVs, and with the advent of new technology such as Quantum Dot, Samsung is getting even better at producing a great image. One area that you might expect to find this Quantum Dot technology being used is for medical uses, but that’s just what researchers have been exploring recently.

Explaining a Quantum Dot can become quite tricky, but to cut a long story short, they are semiconductors that are so small they register at the nanoscale side of things. In terms of Quantum Dots used in television displays, it’s their ability to precisely tune to a specific and exact part of the color spectrum that makes them so attractive, not to mention their much lower power draw. Now, Kim Sung-jee, a professor of the Chemistry department at Pohang University of Science and Technology (POSTECH), has said that “when combining protein which clings to cancer cells and quantum dots, it can be used to seek out cancer cells in the body”. It’s reasoned that the potential for these Quantum Dots to be so precise in terms of color reproduction can help physicians track down certain cancer cells.

Myung Seung-jae, chief director of Biomedical Research Center at Asan Institute for Life Sciences who joined Professor Kim in researching Quantum Dots to fight cancer, said that when a test was ran on animals with Cancer cells in their bodies drugs with Quantum Dots “attacked only cancer cells. When quantum dots meet cancer cells, they detect the change of potential of hydrogen (pH) and anti-cancer drugs”. So, while it seems a long way off, it looks like the same technology that makes for a more accurate and engaging picture for your TV could be used in order to fight cancer or at least better identify types of Cancer and how to combat them inside of the body.

Continue reading “Samsung’s Quantum Dot TV Tech to Find Medical Applications” | >

A study performed at IRB Barcelona offers an explanation as to why the genetic code stopped growing 3,000 million years ago. This is attributed to the structure of transfer RNAs—the key molecules in the translation of genes into proteins. The genetic code is limited to 20 amino acids—the building blocks of proteins—the maximum number that prevents systematic mutations, which are fatal for life. The discovery could have applications in synthetic biology.

Nature is constantly evolving—its limits determined only by variations that threaten the viability of species. Research into the origin and expansion of the are fundamental to explain the evolution of life. In Science Advances, a team of biologists specialised in this field explain a limitation that put the brakes on the further development of the genetic code, which is the universal set of rules that all organisms on Earth use to translate genetic sequences of nucleic acids (DNA and RNA) into the that comprise the proteins that undertake cell functions.

Headed by ICREA researcher Lluís Ribas de Pouplana at the Institute for Research in Biomedicine (IRB Barcelona) and in collaboration with Fyodor A. Kondrashov, at the Centre for Genomic Regulation (CRG) and Modesto Orozco, from IRB Barcelona, the team of scientists has demonstrated that the genetic code evolved to include a maximum of 20 and that it was unable to grow further because of a functional limitation of transfer RNAs—the molecules that serve as interpreters between the language of genes and that of proteins. This halt in the increase in the complexity of life happened more than 3,000 million years ago, before the separate evolution of bacteria, eukaryotes and archaebacteria, as all organisms use the same code to produce proteins from genetic information.

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Neurons created from chemically induced neural stem cells. The cells were created from skin cells that were reprogrammed into neural stem cells using a cocktail of only nine chemicals. This is the first time cellular reprogramming has been accomplished without adding external genes to the cells. (credit: Mingliang Zhang, PhD, Gladstone Institutes)

Scientists at the Gladstone Institutes have used chemicals to transform skin cells into heart cells and brain cells, instead of adding external genes — making this accomplishment a breakthrough, according to the scientists.

The research lays the groundwork for one day being able to regenerate lost or damaged cells directly with pharmaceutical drugs — a more efficient and reliable method to reprogram cells and one that avoids medical concerns surrounding genetic engineering.

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