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Category: 3D printing – Page 7

Kombucha-derived bioink developed for personalized tissue repair

Tissue engineering utilizes 3D printing and bioink to grow human cells on scaffolds, creating replacements for damaged tissues like skin, cartilage, and even organs. A team of researchers led by Professor Insup Noh from Seoul National University of Science and Technology, Republic of Korea, has developed a bioink using nanocellulose derived from Kombucha SCOBY (Symbiotic Culture of Bacteria and Yeast) as the scaffold material.

The biomaterial offers a sustainable alternative to conventional options, and it can be loaded onto a hand-held “Biowork” biopen, also developed by the same team. The digital biopen allows the precise application of bioink to damaged defected areas, such as irregular cartilage and large skin wounds, paving the way for more personalized and effective in vivo tissue repair, eliminating the need for in vitro processes.

This paper was published in the International Journal of Biological Macromolecules on 1 December 2024.

Safe bioink for artificial organ printing

The development of biomaterials for artificial organs and tissues is an active area of research due to increases in accidental injuries and chronic diseases, along with the entry into a super-aged society. 3D bioprinting technology, which uses cells and biomaterials to create three-dimensional artificial tissue structures, has recently gained popularity. However, commonly used hydrogel-based bioinks can cause cytotoxicity due to the chemical crosslinking agent and ultraviolet light that connect the molecular structure of photocuring 3D-printed bioink.

Dr. Song Soo-chang’s research team at the Center for Biomaterials, Korea Institute of Science and Technology (KIST), revealed the first development of poly(organophosphazene) hydrogel-based temperature-sensitive that stably maintained its physical structure by temperature control only without photocuring, induced tissue regeneration, and then biodegraded in the body after a certain period of time.

Current hydrogel-based bioinks must go through a photocuring process to enhance the mechanical properties of the 3D scaffold after printing, with a high risk of adverse effects in the human body. In addition, there has been a possibility of side effects when transplanting externally cultured cells within bioink to increase the tissue regeneration effect.

Encoding many properties in one material via 3D printing

A class of synthetic soft materials called liquid crystal elastomers (LCEs) can change shape in response to heat, similar to how muscles contract and relax in response to signals from the nervous system. 3D printing these materials opens new avenues to applications, ranging from soft robots and prosthetics to compression textiles.

Controlling the material’s properties requires squeezing this elastomer-forming ink through the of a 3D printer, which induces changes to the ink’s internal structure and aligns rigid building blocks known as mesogens at the molecular scale. However, achieving specific, targeted alignment, and resulting properties, in these shape-morphing materials has required extensive trial and error to fully optimize printing conditions. Until now.

In a new study, researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Princeton University, Lawrence Livermore National Laboratory, and Brookhaven National Laboratory worked together to write a playbook for printing liquid crystal elastomers with predictable, controllable alignment, and hence properties, every time.

3D printing approach for shape-changing materials means better biomedical, energy, robotics devices

An Oregon State University researcher has helped create a new 3D printing approach for shape-changing materials that are likened to muscles, opening the door for improved applications in robotics as well as biomedical and energy devices.

The liquid crystalline elastomer structures printed by Devin Roach of the OSU College of Engineering and collaborators can crawl, fold and snap directly after printing. The study is published in the journal Advanced Materials.

“LCEs are basically soft motors,” said Roach, assistant professor of mechanical engineering. “Since they’re soft, unlike regular motors, they work great with our inherently soft bodies. So they can be used as implantable medical devices, for example, to deliver drugs at targeted locations, as stents for procedures in target areas, or as urethral implants that help with incontinence.”

Machine Learning Designs Materials As Strong As Steel and As Light As Foam

To design their improved materials, Serles and Filleter worked with Professor Seunghwa Ryu and PhD student Jinwook Yeo at the Korea Advanced Institute of Science & Technology (KAIST) in Daejeon, South Korea. This partnership was initiated through U of T’s International Doctoral Clusters program, which supports doctoral training through research engagement with international collaborators.

The KAIST team employed the multi-objective Bayesian optimization machine learning algorithm. This algorithm learned from simulated geometries to predict the best possible geometries for enhancing stress distribution and improving the strength-to-weight ratio of nano-architected designs.

Serles then used a two-photon polymerization 3D printer housed in the Centre for Research and Application in Fluidic Technologies (CRAFT) to create prototypes for experimental validation. This additive manufacturing technology enables 3D printing at the micro and nano scale, creating optimized carbon nanolattices.

NASA and Rocket Lab Enter a New Era With the Neutron Rocket

3D printing news News NASA and Rocket Lab Enter a New Era With the Neutron Rocket.

Published on January 27, 2025 by Madeleine P.

With the goal of further expanding its reach in space missions, NASA has signed an agreement with Rocket Lab USA, Inc. to integrate the Neutron rocket into the VADR program. This is a program to procure launch services at competitive prices and reduce mission requirements for spacecraft that have not yet been launched into orbit. Neutron is a medium-range launch vehicle manufactured by Rocket Lab USA that is partially reusable and powered by nine 3D-printed Archimedes engines designed to increase the efficiency and flexibility of space launches.

Researchers design mind-blowing construction material to replace steel: ‘This technology holds a lot of promise’

Researchers at the University of Maine have managed to 3D print an organic building material with the strength of steel.

The SM2ART Nfloor is printed as a single piece in about 30 hours, which is a third faster than building something comparable by hand according to TechXplore.

The nice thing about this set-up is that these panels can be printed in bulk off-site and get shipped to the construction area. Since there are already channels in the floor for electrical and plumbing, the only other thing that needs to be applied by hand is soundproofing and floor covering.