This cohort study compares real-world overall survival between sequential and concurrent radiotherapy and immunotherapy among patients with newly diagnosed advanced non–small cell lung cancer.
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Light-activated gel could transform wearables, soft robotics, and more
Consider the chief difference between living systems and electronics: the first is generally soft and squishy, while the latter is hard and rigid. Now, in work that could impact human-machine interfaces, biocompatible devices, soft robotics, and more, MIT engineers and colleagues have developed a soft, flexible gel that dramatically changes its conductivity upon the application of light.
Enter the growing field of ionotronics, which involves transferring data through ions, or charged molecules. Electronics does the same with electrons. But while the latter is well established, ionotronics is still being developed, with one huge exception: living systems. The cells in our bodies communicate with a variety of ions, from potassium to sodium.
Ionotronics, in turn, can provide a bridge between electronics and biological tissues. Potential applications range from soft wearable technology to human-machine interfaces.
Nishida Kitarō‘s Absolute Dialetheism
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New experiment will try to coax virtual particles out of the vacuum
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My favourite physics paper of the week is a new idea for how to coax virtual particles out of the quantum vacuum and into revealing themselves.
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Negative Time is Real, Physicists Confirm. Kind Of
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In a new paper, a group of physicists claims to have confirmed the existence of “negative time.” I had never heard of this, but I had a look at the paper. And I think I have figured it out.
Paper: https://arxiv.org/abs/2409.
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Longevity Scientist: Aging Will Soon Be Treatable But Immortality Is Not the Goal
Can we really slow aging or even reverse it?
Aging is no longer viewed as an untouchable part of life. According to Eric Verdin, scientists are beginning to treat aging itself as a biological process that can be slowed and potentially reversed.
In this episode, Eric explains why longevity research is entering a new era. He discusses how AI, women’s health, metabolic therapies, and partial reprogramming are reshaping medicine. He highlights GLP-1 drugs as one of the most promising tools today and explains how resetting cells to a younger state may one day restore function in aging tissues.
He also shares the most effective strategies available right now: exercise, sleep, nutrition, mental stimulation, and social connection. While supplements like Creatine may help, Eric stresses that lifestyle remains the foundation of long-term health.
Eric Verdin is a physician-scientist and CEO of the Buck Institute for Research on Aging, where he leads research focused on extending human healthspan.
What You’ll Learn.
AI generates full battery electrolyte recipes, matching top lithium metal battery performance
Battery electrolytes aren’t just one chemical, but a complex mixture of salts, solvents, and additives interacting and reacting with each other. Artificial intelligence has made great headway in helping select ideal materials to go into that chemical soup. But a team from the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) is using AI to generate the entire formulation, balancing the complicated tradeoffs and interactions that go into the electrolytes that make batteries possible.
The research is published in JACS Au. It is the next step in the Amanchukwu Lab’s ongoing development of an AI for battery work, ElectrolyteGPT.
“Next-generation battery electrolytes must meet multiple, often conflicting property requirements,” said first author Jaemin Kim. “With the model’s capability of generating outputs under diverse conditions, ElectrolyteGPT is able to generate novel candidates satisfying the desired properties simultaneously.”