An “immune system reset” cured autoimmune, or Type 1, diabetes in mice in a Stanford Medicine study. The approach may be useful for other autoimmune conditions as well as organ transplants.
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Hidden high-energy water reveals a new molecular force
Water trapped inside tiny molecular cavities behaves in a surprisingly energetic way, pushing outward like people crammed in an elevator. When a new molecule enters these narrow spaces, the confined water forces its way out—boosting the strength of the molecular bond that forms in its place. Researchers from KIT and Constructor University have now proven this effect both experimentally and theoretically, showing that these “highly energetic” water molecules can dramatically influence how other molecules interact.
Function of the Spine
Your spine is an important bone structure that supports your body and helps you walk, twist and move. Your spine is made up of vertebrae (bones), disks, joints, soft tissues, nerves and your spinal cord. Exercises can strengthen the core muscles that support your spine and prevent back injuries and pain.
Learn more about what your spine does and how this bone structure is important for your health.
Ultrasonic device dramatically speeds harvesting of water from the air
MIT engineers designed an ultrasonic system to “shake” water out of an atmospheric water harvester.
MIT researchers designed a device that quickly recovers drinking water from an atmospheric water harvesting material. The system uses ultrasonic waves to shake the water out of the material, recovering water in minutes.
Promising Effects of CAR T-Cell Therapy in Refractory Stiff Person Syndrome and a Hopeful Future for All Neuroautoimmunities
Via OPG_BOEx: Clinical translation of photoacoustic imaging using exogenous molecular contrast agents [Invited] https://bit.ly/4occZgi
A team from Rice University examines the current status and future potential of contrast-enhanced PAI in human applications.
In their results, the team proposed neuro-oncology as a novel application, effectively addressing the limitations of intraoperative fluorescence imaging.
Photoacoustic imaging (PAI) combines optical contrast with acoustic detection to enable high-resolution, molecular imaging at clinically relevant depths. This review outlines the current status and future potential of contrast-enhanced PAI in human applications. We begin by discussing regulatory considerations surrounding both imaging devices and exogenous contrast agents, highlighting safety concerns, lack of standardized validation protocols, and barriers to the approval of novel agents. To accelerate clinical adoption, many studies have focused on repurposing FDA-approved agents such as indocyanine green, methylene blue, and clofazimine, which offer favorable optical properties and known safety profiles. We then review clinical applications of contrast-enhanced PAI across organ systems. In lymphatic imaging, PAI enables noninvasive visualization of lymphatic vessels and sentinel lymph nodes. Prostate imaging benefits from improved tumor delineation, and vascular applications leverage PAI to assess oxygen saturation and vascular remodeling. In gastrointestinal and hepatic imaging, PAI supports functional assessment and lesion detection with enhanced contrast. Emerging applications in neuro-oncology demonstrate the potential of PAI for intraoperative guidance and brain tumor imaging. Compared to fluorescence imaging, PAI provides deeper penetration and quantifiable contrast. Studies using both approved and investigational agents, including gold nanorods and targeted dye conjugates, highlight advances in imaging tumor margins. Progress in transcranial PAI and molecular probe design continues to broaden its capabilities. Together, these developments underscore the expanding clinical utility of contrast-enhanced PAI for real-time, functional, and molecular imaging.
Electric Fields Steer Nanoparticles for Targeted Drug Delivery
Researchers discovered a new way to independently tune a nanoparticle’s speed and direction using different strength electric fields.
The new method could lead to better drug delivery technologies.
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A new method using a combination of strong and weak electric fields to change nanoparticle speed and direction could improve drug delivery and purification systems.
GLP-1 Drug Side Effects May Be Tackled with More Mechanistic Studies
GLP-1 drugs have been transformative for treating obesity, but about 50 percent of patients who were prescribed this treatment ended up stopping due to severe side effects, such as nausea.
At the 2025 Society for Neuroscience meeting, experts presented new findings on how GLP-1 agonists’ action in the brain produced unwanted side effects and how these discoveries can guide future research.
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At the 2025 Society for Neuroscience meeting, scientists discussed the adverse side effects of GLP-1 agonists and new directions for future research.
Narcissism and its role in sexually motivated serial killers
Researchers at the University of Bamberg have traced a darkly intricate form of narcissism in sexually motivated male serial killers, reporting that many offenders combine brittle sensitivity with a craving for admiration and dominance leans on the killers’ own words from confessions and interrogations rather than psychiatric labels alone.
Serial killers have fascinated and frightened audiences for centuries, with media portrayals ranging from monstrous to romanticized. According to the FBI’s Serial Murder Symposium, serial murder involves the unlawful killing of two or more victims by the same offender in separate events.
For decades, many police and forensic teams have grouped serial killers into categories by motive: visionary killers driven by psychosis and hallucinations, thrill killers who pursue excitement and pleasure through killing, mission-oriented offenders who believe they must eliminate specific groups, power/control killers who seek total dominance over their victims, often including sexual abuse, and those whose crimes revolve around lust.