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Wearable ultrasound patch boosts REM sleep without drugs or surgery
REM sleep disruptions have been associated with depression, anxiety and post-traumatic stress disorder (PTSD). Current approaches to sleep problems, including medication and behavioral therapy, may cause side effects or may not directly address the underlying factors that interfere with REM sleep.
Future Trials for Insomnia, Depression and PTSD
The team plans to conduct larger studies to verify the initial results and evaluate whether NEUSLeeP could help people with PTSD, depression and chronic insomnia. The researchers also see potential uses in home sleep monitoring, neuroscience research and personalized sleep treatments.
A Florida diver, after more than 20,000 dives, built an underwater nursery that grew 25,000 threatened corals for dying reefs
Along Florida’s barrier reef, the only living coral barrier reef in the United States and the third largest barrier reef system in the world, marine scientists and coastal communities have witnessed decades of severe ecological collapse. Widespread coral bleaching, rising sea surface temperatures, ocean acidification, and infectious conditions such as stony coral tissue loss disease have drastically reduced historic living coral cover across the Florida Keys.
Large File Support
19 years ago I bought version 6 of some software. I just started using it again after not using it for 17 years or so and it is at version 26 and my old registration is still valid so I still have the pro version! They don’t even sell this software anymore, they just rent it but they are honoring my old purchase!
The software is EmEditor. I originally used it for UTF-8 support but this support became more common with editors. I just used it because I was working with a fairly large text file at 12.5 GB. My main editor is 32-bit and couldn’t remotely handle this. I then tried Windows Notepad and Microsoft Word and they also laughed at the idea of editing such a big file.
EmEditor is capable of opening very large files — up to 16 TB or 1,099 billion lines — with only a little memory, leaving you free to work as large or small as you please.
What Samsara’s Insider Selling Really Signals For IIoT
Samsara insiders have sold a net $57 million over the past year, including major sales by the CEO and board member Marc Andreessen — while analyst coverage remains strongly bullish.
The gap between public optimism and sustained private divestment is the signal worth watching.
For manufacturers and fleet operators evaluating IIoT platforms: net insider selling over a 12-month window is a legitimate due-diligence input. It doesn’t override growth metrics, but it shouldn’t be dismissed as pure noise either.
Full analysis: [ https://creedtec.online/what-samsaras-insider-selling-really-signals-for-iiot/](https://creedtec.online/what-samsaras-insider-selling-really-signals-for-iiot/)
#IndustrialIoT #IIoT #Samsara
Samsara’s insider selling tops $57M as analysts stay bullish. Here’s what the pattern really signals for industrial IoT buyers and investors.
Drug temporarily reverses autism-like brain changes in adult mice within hours
A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but those brain and behavioral effects may be rapidly, though temporarily, reversible in adulthood with a single dose of the immunosuppressive drug rapamycin.
Even mild inflammation during midpregnancy has been shown to result in autism-like symptoms in offspring, abnormal brain growth, seizures and heightened sensitivity to everyday sensory input that persist into adulthood.
In the study published in the journal Nature Communications, UCLA researchers found that a single dose of rapamycin significantly improved brain signaling and behavioral symptoms in these offspring within about two hours, too short a time to correct underlying physical brain changes caused by maternal inflammation.
Researchers Find a Way To Make Pancreatic Cancer Visible to the Immune System
A combination treatment exposed hidden pancreatic cancer cells to the immune system, reduced their spread, and helped mice live longer.
Researchers at the University of Minnesota Medical School have uncovered one reason pancreatic cancer is so difficult for the immune system to recognize and attack. The discovery points to a potential way to make immunotherapy more effective against a disease that has historically resisted many immune-based treatments.
The findings, published in Science Immunology, show that some pancreatic cancer cells can avoid destruction by shutting down the molecular system that normally reveals them to immune cells. Once these cells become harder to detect, they are more likely to survive, spread, and establish tumors elsewhere in the body.
Long-pulse fast ignition in magnetized liner inertial fusion
The fast-ignition paradigm for inertial confinement fusion allows for extremely high gains but requires fuel to be heated very quickly to outpace hotspot disassembly and energy losses. This demands lasers with high power and intensity, posing engineering challenges that have called into question the fundamental practicality of fast ignition. Magnetized liner inertial fusion (MagLIF) circumvents these problems through its large-aspect-ratio cylindrical geometry and strong axial magnetic fields that allow for ignition at lower areal densities. Furthermore, MagLIF’s large aspect ratio and higher yields relax other constraints on energy deposition and repetition rate, while its axial magnetic fields can be used to collimate ignitor electrons and thereby increase allowed standoff distance and save on ignitor energy. This tremendous overall relaxation of the engineering constraints that have historically limited the practicality of fast ignition suggests that the paradigm may be considerably more viable in a MagLIF context.