An MRI scan revealed a brain tumor located in a difficult area, and performing a biopsy would carry significant risks for the patient, who had initially sought medical help due to double vision. Cases like this, discussed by a multidisciplinary team of cancer specialists, led researchers at Charité – Universitätsmedizin Berlin, along with their collaborators, to search for alternative diagnostic methods.
Their solution is an AI model that analyzes specific features in the genetic material of tumors, particularly their epigenetic fingerprint, which can be obtained from sources such as cerebrospinal fluid. As reported in the journal Nature Cancer, the model classifies tumors both rapidly and with high accuracy.
Researchers led by John T. Wilson, Vanderbilt University associate professor of chemical and biomolecular engineering and biomedical engineering, have developed a new approach using a molecularly designed nanobody platform that seeks to make immunotherapy more effective in the treatment of cancer.
The research, “Potentiating Cancer Immunotherapies with Modular Albumin-Hitchhiking Nanobody-STING Agonist Conjugates,” is published in Nature Biomedical Engineering.
Immunotherapy is revolutionizing cancer treatment, but few patients benefit from the treatment, according to researchers. However, Wilson and his Immunoengineering Lab at Vanderbilt, along with collaborators at Vanderbilt University Medical Center, SOMBS, and the College of Arts and Sciences, aim to solve this problem.
Researchers have now shown that, despite individual differences in neuron activity, a shared underlying structure guides the brain toward unified decisions.
IN A NUTSHELL 🔋 Researchers in South Korea developed a cost-effective MoS2 thin film that boosts battery lifespan sevenfold. 💡 The innovation uses molybdenum disulfide to prevent dendrite formation, enhancing the safety and performance of anode-free solid-state batteries. 🌟 This breakthrough offers a scalable, affordable alternative to noble metals, promising to accelerate the commercialization of
IN A NUTSHELL 🌍 North Star, developed by an ex-Harvard professor, is an AI tool designed to predict and prevent wars by simulating world leaders’ decisions. 🔮 The tool creates digital twins of leaders to foresee outcomes of geopolitical events, offering insights for better decision-making. 💼 Investors see peace tech as a burgeoning market, drawing
A new study has revealed compelling evidence that brain criticality—a dynamic balance between neural excitation and inhibition—has a strong genetic foundation and is associated with cognitive performance. The research was published on June 23 in the Proceedings of the National Academy of Sciences.
Led by Prof. Liu Ning from the Institute of Biophysics of the Chinese Academy of Sciences (CAS) and Prof. Yu Shan from the Institute of Automation of CAS, the team analyzed resting-state functional MRI (rs-fMRI) data from the Human Connectome Project S1200 release. The dataset included 250 monozygotic twins, 142 dizygotic twins, and 437 unrelated individuals, providing a robust framework for examining the heritability of critical brain dynamics.
The results showed that brain criticality is significantly influenced by genetic factors, with stronger genetic effects observed in primary sensory cortices compared to higher-order association regions. These findings suggest that the capacity of the brain to maintain near-critical dynamics—previously associated with optimal information processing and cognitive flexibility—is, to a substantial degree, inherited.
Greg Egan’s Diaspora is one of the most ambitious and mind-bending science fiction novels ever published. It came out in 1997 and originally started as a short story called “Wang’s Carpets.” That story ended up as a chapter in the novel. Diaspora is: dense, smart, and way ahead of its time. This is hard science fiction to the core. Egan invents entire new branches of physics. He reimagines life, consciousness, time, space — even what it means to be human. The book doesn’t ease you in. There’s a glossary, invented physics theories like Kozuch Theory, and characters that don’t even have genders. But if you stick with it, what you get isn’t just a story, it’s a look at what the future might actually become. By the year 2,975, humanity isn’t one species anymore. It’s split into three groups: Fleshers: The biological humans, including the “statics” (unchanged baseline humans) and all sorts of heavily modified versions — underwater people, gene-hacked thinkers, even “dream apes” who gave up speech to live closer to nature. Gleisners: AIs in robotic bodies that live in space. They care about the physical world and experience time like regular humans. They’re kind of old-school — still sending ships to the stars, trying to build things in real space. Citizens: These are digital minds that live entirely in simulated worlds called polises.
👽 Please consider supporting this channel on Patreon: / ideasoficeandfire. or PAYPAL — https://paypal.me/QuinnsIdeas?locale… 🎨 Art: Adobe Licensed. 🎵 Music: / @jamezdahlmusic 📚 Get These Books! Affiliate link* https://amzn.to/3HSixNx Quinn’s Discord: / discord FOLLOW QUINN ON TWITTER: Twitter: / ideasofice_fire I NOW HAVE A SUBREDDIT: / ideasoficeandfire Quinn’s New Graphic Novel: https://www.quinnhoward.net/theliebeh… Quinn’s Comic Books: https://www.quinnhoward.net/shop Quinn’s Website: https://www.quinnhoward.net Like me on Facebook!: / ioiaf 🎥 Mentioned Videos 🎬 Other Playlist Three-Body Playlist: • Three Body Problem H.P. Lovecraft Playlist: • LOVECRAFT Hyperion Playlist: • Hyperion Dune Playlist: • Dune Lore Explained Foundation Playlist: • Isaac Asimov Feel free to leave a comment like and subscribe! Thanks For Watching!.
IN A NUTSHELL 🔬 MIT researchers have developed a superconducting diode-based rectifier that converts AC to DC on a single chip. 💡 This innovation could streamline power delivery in ultra-cold quantum systems, reducing electromagnetic noise and interference. 🔍 The technology is crucial for enhancing qubit stability and could significantly impact dark matter detection circuits at
A rare genetic mutation known as APOE3-R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling in the brain’s immune cells.
