MIT scientists have developed nanoparticles that reprogram immune cells directly inside the body to attack cancer and harmful immune cells, eliminating tumors and reversing liver damage in mouse experiments. The breakthrough could make powerful immune therapies dramatically simpler and less expensive while opening new possibilities for treating cancer and autoimmune diseases.
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Taiwan-Based Hacker Used BOSSAI AI Agents to Steal Taipei Emergency Dispatch Records
A single attacker using AI agents pulled emergency dispatch records covering seven Taipei districts, researchers at Acronis’s Threat Research Unit said last week.
The agents also found a Taipei fire department platform exposing patient data from 2018, including ECG readings and ambulance video footage, without a login.
The researchers are highly confident that the attacker is a single person based in Hualien City, Taiwan. He aimed the agents at hundreds of organizations in at least 11 countries, including emergency services, banks, universities and military systems. The agents collected data or accessed systems at about 10 of them in Taiwan, Mexico and Thailand.
New medication may ‘cure’ high blood pressure years after you stop
New research into baxdrostat, a drug that blocks the hormone aldosterone, suggests it may reverse a key cause of hypertension
Dry Eye Disease: Beyond Tear Deficiency
Dry eye disease (DED) is a multifactorial ocular surface disease characterized by loss of tear film homeostasis, with tear film instability, hyperosmolarity, inflammation, ocular surface damage, and neurosensory abnormalities contributing to symptoms and visual disturbance. This disease may involve aqueous-deficient, evaporative, or mixed mechanisms.
Medscape spoke with Christopher J. Rapuano, MD, chief of the Cornea Service at Wills Eye Hospital and professor of ophthalmology at Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, about reframing DED within the broader context of ocular surface disease, evaluating alternative causes of ocular discomfort, and selecting management according to the underlying disorder.
Default ‘admin: admin’ Server Password Helps Researchers Hack Two Automakers, Unlock and Start Cars
ForgeRock misconfigurations let researchers hijack accounts at two car brands and remotely unlock and start connected vehicles.
The Pocket Computer CEOs Used In 2007 😳#shorts
In 2007, just as the original iPhone was introduced, personal digital assistants (PDAs) were at the absolute peak of industrial design. The ASUS MyPal A626 st…
Radical Computing Evolution
Where is mainstream computing headed? And do we need a new mindset for the age of AI and the SiP?
Related @ExplainingComputers videos include:
“GPU Upgrade for Local AI”: • GPU Upgrade for Local AI
“The Future of Home Computing”: • The Future of Home Computing: Radical Chan…
“AI & the Future of the Web”: • AI & the Future of the Web.
ZX81: • ZX81 Classic PC
Artificial quantum brain: A bold proposal
The paper discusses the possibility of building an elemental unit of an artificial quantum brain using self-assembly, featuring resonant synchronization and the
CAR T cells in solid tumors: challenges and opportunities
CARs are simulated receptors containing an extracellular single-chain variable fragment (scFv), a transmembrane domain, as well as an intracellular region of immunoreceptor tyrosine-based activation motifs (ITAMs) in association with a co-stimulatory signal.
An Integrated Hydrogeological and Hydrogeochemical Approach for Distinguishing Point-Source Contamination from Natural Background Levels at a Landfill Site The La Silva Case, Cassano Allo Ionio (Southern Italy)
The report presents an integrated hydrogeological, geochemical, and geophysical investigation of a municipal solid waste landfill area located in Cassano allo Ionio (CS), Southern Italy. The study aimed to characterize the local subsurface, assess groundwater quality, and determine whether the elevated concentrations of iron (Fe) and manganese (Mn) are attributable to landfill-related contamination or to naturally occurring geogenic processes. The investigation identified a deep aquifer hosted within Pliocene conglomeratic deposits, characterized by low intrinsic vulnerability and groundwater flow predominantly toward the southeast, although locally complex piezometric conditions were observed. Although iron and manganese concentrations exceeded regulatory contamination thresholds in several monitoring wells, their spatial distribution, the prevailing redox conditions, their occurrence at upgradient locations, and comparison with surface waters and a nearby agricultural well indicate that these anomalies are more consistent with natural water-rock interactions and reductive dissolution processes within sandy-conglomeratic layers containing silty-clayey lenses than with the presence of a landfill-derived leachate plume. Geophysical investigations also contributed to delineating the geometry of the landfill and estimating the depth of the waste deposits, thereby supporting a more comprehensive characterization of the site.
Groundwater, Landfill, Iron, Manganese, Natural Background Levels, Redox Conditions, Hydrogeochemistry, Site-Specific Conceptual Model