Lifeboat Foundation: Safeguarding Humanity
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Exactly when and where did life on Earth begin? Scientists have long thought that it emerged three billion years ago in the ocean — until astrobiologist Tara Djokic and her team made an unexpected discovery in the western Australian desert. Learn how an ancient rock found near a hot volcanic pool is shifting our understanding of the origin-of-life puzzle.

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Continue reading “This ancient rock is changing our theory on the origin of life | Tara Djokic” | >

Everis, an NTT DATA company and one of Spain’s largest managed service providers (MSP), had its computer systems encrypted today in a ransomware attack, just as it happened to Spain’s largest radio station Cadena SER (Sociedad Española de Radiodifusión).

While the ransomware attacks were not yet publicly acknowledged by the company, the ransom note left on Everis’ encrypted computers has already leaked and BleepingComputer can confirm that the MSP’s data was infected using the BitPaymer ransomware.

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From raindrops rolling off the waxy surface of a waterlily leaf, to the efficiency of desalination membranes, interactions between water molecules and water-repellent “hydrophobic” surfaces are all around us. The interplay becomes even more intriguing when a thin water layer becomes sandwiched between two hydrophobic surfaces, KAUST researchers have shown.

In the early 1980s, researchers first noted an unexpected effect when two hydrophobic surfaces were slowly brought together in water. “At some point, the two surfaces would suddenly jump into contact—like two magnets being brought together,” says Himanshu Mishra from KAUST’s Water Desalination and Reuse Center. Mishra’s lab investigates water at all length scales, from reducing water consumption in agriculture, to the properties of individual water molecules.

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When the first smartphones arrived, few people understood how they would change our reality. Today, our internet-connected mobile device maps our travel, manages our finances, delivers our dinner, and connects us to every corner of human knowledge. In less than a generation, it has become almost an extension of our central nervous system — so indispensable that we can’t imagine leaving home without it to guide us.

We are about to embark on another journey even more important to every individual and to human society. We are entering the age of genomics, an amazing future that will dramatically improve the health outcomes of people across the planet. Soon, we won’t be able to imagine a time when we left home without knowledge of our genome to guide us.

But this future isn’t a generation away. As early as 2020, I believe we will be living in a world where software uses knowledge of our personal genome to guide us, like a health GPS, toward choices that are appropriate for us as individuals. From the foods we choose to eat to the medicines we take to prevent or cure disease, from helping us avoid exposure to environmental risks to eradicating thousands of genetic diseases, genomics will reveal such immense possibilities that it will feel as if we can see and hear for the first time.

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With ageing, intrinsic haematopoietic stem cell (HSC) activity decreases, resulting in impaired tissue homeostasis, reduced engraftment following transplantation and increased susceptibility to diseases. However, whether ageing also affects the HSC niche, and thereby impairs its capacity to support HSC function, is still widely debated. Here, by using in-vivo long-term label-retention assays we demonstrate that aged label-retaining HSCs, which are, in old mice, the most quiescent HSC subpopulation with the highest regenerative capacity and cellular polarity, reside predominantly in perisinusoidal niches. Furthermore, we demonstrate that sinusoidal niches are uniquely preserved in shape, morphology and number on ageing. Finally, we show that myeloablative chemotherapy can selectively disrupt aged sinusoidal niches in the long term, which is linked to the lack of recovery of endothelial Jag2 at sinusoids. Overall, our data characterize the functional alterations of the aged HSC niche and unveil that perisinusoidal niches are uniquely preserved and thereby protect HSCs from ageing.

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Too large to be classed as molecules, but too small to be bulk solids, atomic clusters can range in size from a few dozen to several hundred atoms. The structures can be used for a diverse range of applications, which requires a detailed knowledge of their shapes. These are easy to describe using mathematics in some cases; while in others, their morphologies are far more irregular. However, current models typically ignore this level of detail; often defining clusters as simple ball-shaped structures.

In research published in The European Physical Journal B, José M. Cabrera-Trujillo and colleagues at the Autonomous University of San Luis Potosí in Mexico propose a new method of identifying the morphologies of atomic clusters. They have now confirmed that the distinctive geometric shapes of some clusters, as well as the irregularity of amorphous structures, can be fully identified mathematically.

The insights gathered by Cabrera-Trujillo’s team could make it easier for researchers to engineer atomic clusters for specific applications. These could include nanoparticles containing two different metals, which are highly effective in catalysing chemical reactions. Their updated methods provided new ways to determine the structural properties of clusters, the ways in which they convert energy to different forms, and the potential forces between atoms. The technique was also able to distinguish the surrounding environments of atoms in the cores of clusters, and on their surfaces. Ultimately, this allowed the researchers to distinguish between distinctive shapes, including icosahedrons, octahedrons, and simple pancakes. They were also able to identify amorphous shapes, which contain no discernible mathematical order.

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