Lifeboat Foundation

Revealing yet another super-power in the skillful squid, scientists have discovered that squid massively edit their own genetic instructions not only within the nucleus of their neurons, but also within the axon — the long, slender neural projections that transmit electrical impulses to other neurons. This is the first time that edits to genetic information have been observed outside of the nucleus of an animal cell.

The study, led by Isabel C. Vallecillo-Viejo and Joshua Rosenthal at the Marine Biological Laboratory (MBL), Woods Hole, is published this week in Nucleic Acids Research.

The discovery provides another jolt to the “central dogma” of molecular biology, which states that genetic information is passed faithfully from DNA to messenger RNA to the synthesis of proteins. In 2015, Rosenthal and colleagues discovered that squid “edit” their messenger RNA instructions to an extraordinary degree — orders of magnitude more than humans do — allowing them to fine-tune the type of proteins that will be produced in the nervous system.

Doctor groups are recommending testing and isolation for people who lose their ability to smell and taste, even if they have no other symptoms.

We may have it all wrong when it comes to this accidental invasive species.

Researchers have designed a brain-computer interface to read your mind better than ever.

But don’t think this is a replacement for pumping some iron.

Up-to-date Coronavirus COVID-19 guidance for physicians & pharmacists from Johns Hopkins ABX. Disease spectrum, testing, and clinical trials for vaccines, chloroquine, remdesivir, lopinavir / ritonavir discussed.

Covid-19 lasted for 17 days in the cabins of cruise ships:

Cruise ships are often settings for outbreaks of infectious diseases because of their closed environment and contact between travelers from many countries.

What is added by this report?

Continue reading “Public Health Responses to COVID-19 Outbreaks on Cruise Ships — Worldwide, February–March 2020” »

With more than 39,000 Americans infected with coronavirus, the US is now the third hardest-hit country in the world. New York alone has more than 20,000 cases, with 12,305 in the Big Apple.

When an egg cell of almost any sexually reproducing species is fertilized, it sets off a series of waves that ripple across the egg’s surface. These waves are produced by billions of activated proteins that surge through the egg’s membrane like streams of tiny burrowing sentinels, signaling the egg to start dividing, folding, and dividing again, to form the first cellular seeds of an organism.

Now MIT scientists have taken a detailed look at the pattern of these waves, produced on the surface of starfish eggs. These eggs are large and therefore easy to observe, and scientists consider starfish eggs to be representative of the eggs of many other animal species.

In each egg, the team introduced a protein to mimic the onset of fertilization, and recorded the pattern of waves that rippled across their surfaces in response. They observed that each wave emerged in a spiral pattern, and that multiple spirals whirled across an egg’s surface at a time. Some spirals spontaneously appeared and swirled away in opposite directions, while others collided head-on and immediately disappeared.