Lifeboat Foundation: Safeguarding Humanity
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Scientists said the findings indicated that the virus likely recently jumped from animals to humans, but stressed that additional studies are necessary.

Scientists have reportedly discovered a new kind of coronavirus that is believed to have originated in dogs – in what may be the eighth unique form of the bug known to cause disease in humans.

Researchers in a study published in the Clinical Infectious Diseases journal said their findings from patients hospitalized with pneumonia in 2017–2018 underscored the public health threat of animal coronaviruses, Reuters reported.

They said they had tested nasal swab samples taken from 301 pneumonia patients at a hospital in the east Malaysian state of Sarawak.

Continue reading “Scientists find new human coronavirus that originated in dogs” | >

Most important part comes at 1:49 where Liza talks about gene therapies for people to stop people from aging, reaching homeostasis, or even exceeding it a little bit.

In this video Liz introduces BioViva Science and how the company works with its partners in delivering gene therapies.

Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur, author and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for BioViva and the life sciences. She is actively involved in international educational media outreach and is a founding member of the International Longevity Alliance (ILA). She is the founder of the BioTrove Podcasts, found at iTunes, which is committed to offering a meaningful way for people to learn about current technologies. She is also a founding member of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease.

Continue reading “Fighting Aging With Gene Therapies | Liz Parrish Interview Series Episode 2” | >

Our recent look at the possibility of technosignatures at Alpha Centauri is now supplemented with a new study on the detectability of artificial lights on Proxima Centauri b. The planet is in the habitable zone, roughly similar in mass to the Earth, and of course, it orbits the nearest star, making it a world we can hope to learn a great deal more about as new instruments come online. The James Webb Space Telescope is certainly one of these, but the new work also points to LUVOIR (Large UV/Optical/IR Surveyor), a multi-wavelength space-based observatory with possible launch in 2035.

Authors Elisa Tabor (Stanford University) and Avi Loeb (Harvard) point out that a (presumably) tidally locked planet with a permanent nightside would need artificial lighting to support a technological culture. As we saw in Brian Lacki’s presentation at Breakthrough Discuss (see Alpha Centauri and the Search for Technosignatures), coincident epochs for civilizations developing around neighboring stars are highly unlikely, making this the longest of longshots. On the other hand, a civilization arising elsewhere could be detectable through its artifacts on worlds it has chosen to study.

We learn by asking questions and looking at data. In this case, asking how we would detect artificial light on Proxima b involves factoring in the planet’s radius, which is on the order of 1.3 Earth radii (1.3 R⊕) as well as that of Proxima Centauri itself, which is 0.14 that of the Sun (0.14 R⊙). We also know the planet is in an 11 day orbit at 0.05 AU. Other factors influencing its lightcurve would be its albedo and orbital inclination. Tabor and Loeb use recent work on Proxima Centauri c’s inclination (citation below) to ballpark an orbital inclination for the inner world.

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Astronomers have long predicted that deep beneath Neptune’s thick blue clouds lies a super-hot body of water that, despite its high temperature, never boils because of its incredibly high-pressure atmosphere. Uranus, another planet in the outer solar system of similar size and composition, is also believed to have a similar water-rich interior. Unfortunately, due to their distances from Earth, it is hard to directly probe these two planets to test our assumption. But scientists have found novel ways of testing their theories about these ice giants from Earth.

As described in a newly-published study from Nature Astronomy, scientists recreated the pressure and temperature of the interiors of Neptune and Uranus in a lab. The aim of the experiments was to test hypotheses about the chemistry of the deep water within these planets. But the study could have additional implications for what we know about potentially habitable planets in other solar systems.

“We were seeking to extend our knowledge of the deep interior of ice giants and determine what water-rock interactions at extreme conditions might exist,” said lead author Taehyun Kim, of Yonsei University in South Korea. “Ice giants and some exoplanets have very deep water layers, unlike terrestrial planets. We proposed the possibility of an atomic-scale mixing of two of the planet-building materials (water and rock) in the interiors of ice giants.”

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In our ongoing search to continuously improve our health, we occasionally pay lip service to the bacteria that live inside our gut. Normally this concern rarely manifests as anything more than occasionally remembering to buy some of those small bottles of pro-biotic yoghurts while shopping for your…

Recent discoveries have led to the conclusion that the gut plays an important role in cognitive function, with a large amount of research into understanding what is known as the gut-brain axis, which is the collective name given to the biochemical signalling pathways which take place between the gastrointestinal tract and the central nervous system. With an ever-increasing understanding of this pathway, along with an expanded understand of the gut flora (which was found to decline with age), researchers started to ask how the gut flora are involved in the ageing process.

In order to test how exactly ageing gut flora effects the gut-brain axis, researchers at the University of East Anglia conducted a faecal transplant from elderly mice into younger mice. Following this transplant, the young mice were then put through a serious of tests to assess their cognitive abilities. The younger mice showed significant changes in their microbial profiles, as well as significantly impaired capacity for spatial learning, as well as a decreased capacity for memorisation. These mice also showed an altered expression of proteins associated with neurotransmission and neuroplasticity, along with changes in the mice’s hippocampus, which is responsible for allowing the mice to memories new information, as well as recalling previous memories.

This research has successfully proven a link between the changing microbiome of the gut and protein expression within the central nervous system. This discovery is exceptionally good news, as not only is the problem potentially fairly easy to fix (with an aforementioned faecal transplant), but it also provides clues as to how we might compensate for this age related change in the gut microbiome with medication tailors to mimic the role of a young microbiome. Either way, the discovery has opened the door to a number of exciting prospects for regenerative medicine, along with maybe highlighting the fact that we should really start considering our gut bacteria as more than just a collection of microorganisms, and more of a collection of symbiotic organisms that benefit us in ways that we are only just beginning to understand.

Continue reading “Faecal transplantation: the cure for forgetfulness?” | >

To begin with, why do we use mice in medical and biological research? The answer to this question is fairly straight forward. Mice are cheap, they grow quickly, and the public rarely object to experimentations involving mice. However, mice offer something that is far more important than simple pragmatism, as despite being significantly smaller and externally dissimilar to humans, our two species share an awful lot of similarities. Almost every gene found within mice share functions with genes found within humans, with many genes being essentially identical (with the obvious exception of genetic variation found within all species). This means that anatomically mice are remarkably similar to humans.

Now, this is where for the sake of clarity it would be best to break down biomedical research into two categories. Physiological research and pharmaceutical research, as the success of the mouse model should probably be judges separately depending upon the research that is being carried out. Separating the question of the usefulness of the mouse model down into these two categories also solves the function of more accurately focusing the ire of its critics.

The usefulness of the mouse model in the field of physiological research is largely unquestioned at this point. We have quite literally filled entire textbooks with the information we have gained from studying mice, especially in the field of genetics and pathology. The similarities between humans and mice are so prevalent that it is in fact possible to create functioning human/mouse hybrids, known as ‘genetically engineered mouse models’ or ‘GEMMs’. Essentially, GEMMs are mice that have had the mouse version of a particular gene replaced with its human equivalent. This is an exceptionally powerful tool for medical research, and has led to numerous medical breakthroughs, including most notably our current treatment of acute promyelocytic leukaemia (APL), which was created using GEMMs.

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Astronomers have discovered an exceedingly old star at the edge of our galaxy that seems to have formed only a few million years after the Big Bang – and what they are learning from it could affect their understanding of the birth of the universe.

In a study published last week, researchers found the star during an astronomical survey of the southern sky with a technique called narrowband photometry, which measures the brightness of distant stars in different wavelengths of light and can reveal stars that have low levels of heavy elements.

They then studied the star – known by its survey number as SPLUS J210428.01−004934.2, or SPLUS J2104−0049 for short – with high-resolution spectroscopy to determine its chemical makeup.

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