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A platform for single-molecule measurement of binding kinetics & enzyme activity.

The first molecular electronics chip has been developed, realizing a 50-year-old goal of integrating single molecules into circuits to achieve the ultimate scaling limits of Moore’s Law. Developed by Roswell Biotechnologies and a multi-disciplinary team of leading academic scientists, the chip uses single molecules as universal sensor elements in a circuit to create a programmable biosensor with real-time, single-molecule sensitivity and unlimited scalability in sensor pixel density. This innovation, appearing this week in a peer-reviewed article in the Proceedings of the National Academy of Sciences (PNAS), will power advances in diverse fields that are fundamentally based on observing molecular interactions, including drug discovery, diagnostics, DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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China successfully launched the Gongjian Ludi Tance-1 01A (L-SAR 01A) satellite into a quasi sun-synchronous orbit of 607 kilometers. The 3.2 metric ton satellite was launched at 23:44 UTC on Tuesday, January 25 on a Chang Zheng 4C from the Jiuquan Satellite Launch Center.

The satellite is equipped with an L-band and multi-channel synthetic aperture radar (SAR) payload. It is a civilian satellite that will use a 33 square meter array to survey the Earth after major events such as earthquakes and landslides.

This is comparable to the Argentinian SAOCOM satellites which are also equipped with L-band and a SAR to monitor environmental disasters. L-band brings the advantage of being able to penetrate clouds, rain, and vegetation which makes it easier to monitor the ground. It operates in a frequency range of 1–2 GHz.

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In the search for extraterrestrial intelligence (SETI), we’ve often looked for signs of intelligence, technology and communication that are similar to our own. But as astronomer and SETI trailblazer Jill Tarter points out, that approach means searching for detectable techno signatures, like radio transmissions, not searching for intelligence itself. At the moment scientists are considering whether artificial intelligence (AI) could help us search for alien intelligence in ways we haven’t even thought of yet.

As we think about extraterrestrial intelligence it’s helpful to remember humans are not the only intelligent life on Earth. For all we know, chimpanzees have culture and use tools, spiders process information with webs, cetaceans have dialects, crows understand analogies and beavers are great engineers. Non-human intelligence, language, culture and technology surround us to no end. Alien intelligence could look like an octopus, an ant, a dolphin or a machine or, on the other hand, be radically different from anything on Earth.

#Artificialintelligence #Space #NASA.

Continue reading “U.S. LEAKED: Artificial Intelligence Just Found ALIENS In SPACE” | >

Many of the all-too-familiar symptoms of aging can be attributed to a build-up of senescent cells, those which have stopped dividing. In a new study, researchers in Japan have identified a protein specific to these cells and developed a vaccine that can clear them away, with tests on mice reducing the effects of aging.

Cells cannot keep dividing forever – eventually they accumulate too much DNA damage through environmental stress, so the body shuts them down and flags them to be cleared out by the immune system. This seems to be an evolutionary defense mechanism against cells turning cancerous.

However, even immune cells aren’t immune from this process, and as they become senescent themselves the immune system gradually loses the ability to clear out senescent cells. As these inactive cells accumulate in the body, they contribute to symptoms of aging and the diseases that come with it.

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“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” said Bennett.

The heart was provided by Revivicor, a company based in Virginia that has been engineering pig organs for roughly two decades. In several experiments for pig-to-baboon transplants, the organs survived up to nine months, until the animals passed away due to a lung infection unrelated to the transplant.

Overall, the heart had 10 hefty genetic edits. Three of them wiped out sugar molecules on the outside of cells that provoke an immune response. Six bolstered the chance of the human host accepting the heart—amping up an anti-inflammatory response, preventing blood vessel damage, and dampening any antibodies against the organ. Finally, the last edit limited the pig heart’s size. Although it generally matched the size of a human heart, the team wanted to prevent the pig organ from overgrowth inside Bennett’s chest once it was transplanted—something they previously noticed happened in baboons.

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Over the last year home prices have skyrocketed (along with prices of almost everything else), leaving millions of people unable to afford to move or to change their housing situation. Mortgage lender Freddie Mac estimated last year that the US has a housing supply shortage of 3.8 million homes. It’s partly Covid-related; construction has slowed due to labor shortages, high raw material costs, and supply chain issues—but the problem predates the pandemic, as demand for homes was already outpacing supply in 2019.

Middle-and low-income families have been hit hardest by the housing shortage. In an effort to assist those in need, Habitat for Humanity launched an initiative last year to incorporate 3D printing into its construction process to cut costs. The first home was completed last month, and a family moved in just before Christmas.

Located in Williamsburg, Virginia, the house has three bedrooms and two bathrooms, and the 3D printed portion of it—that is, the exterior walls—took just 28 hours to build. “Build” in this case meant a 3D printer moved along a track in the shape of the house, putting down one layer after another of a cement mixture.

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The amazing thing about radio transients is that if you have enough frequency coverage, you can work out how far away they are. This is because lower radio frequencies arrive slightly later than higher ones depending on how much space they’ve traveled through.

Our new discovery lies about 4,000 light years away—very distant, but still in our galactic backyard.

We also found the radio pulses were almost completely polarized. In astrophysics this usually means their source is a strong magnetic field. The pulses were also changing shape in just half a second, so the source has to be less than half a light second across, much smaller than our sun.

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For millions of patients who have lost limbs – for reasons ranging from diabetes to trauma – the possibility of regaining function through natural regeneration remains out of reach. The regrowth of legs and arms remains limited to animals such as salamanders and the realm of science fiction.

However, a new study published in the journal Science Advances, by scientists at Tufts University and Harvard University’s Wyss Institute, has brought us a step closer to the goal of regenerating human limbs.

On adult frogs, which are naturally unable to regenerate limbs, a research team succeeded in triggering regrowth of a lost leg using a five-drug cocktail applied in a silicone wearable bioreactor dome that seals over the stump for just 24 hours. That brief treatment sets in motion an 18-month period of regrowth that eventually restores a functional leg.

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