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Scanning electron microscopes are one of those niche instruments that most of us don’t really need all the time, but would still love to have access to once in a while. Although we’ve covered a few attempts at home-builds before, many have faltered, except this project over on Hackday. IO by user Vini’s Lab, which appears to be still under active development. The principle of the SEM is pretty simple; a specially prepared sample is bombarded with a focussed beam of electrons, that is steered in a raster pattern. A signal is acquired, using one of a number of techniques, such as secondary electronics (SE) back-scattered electrons (BSE) or simply the transmitted current into the sample. This signal can then be used to form an image of the sample or gather other properties.

The project is clearly in the early stages, as the author says, it’s a very costly thing to build, but already some of the machined parts are ready for assembly. Work has started on the drive electronics for the condenser stigmata lens. This part of the instrument takes the central part of the rapidly diverging raw electron beam that makes it through the anode, and with a couple of sets of octopole coil sets, and an aperture or two, selects only the central portion of the beam, as well as correcting for any astigmatism in the beam. By adjusting the relative currents through each of the coils, a quadrupole magnetic field is created, which counteracts the beam asymmetry.

Scanning control and signal acquisition are handled by a single dedicated card, which utilises the PIO function of a Raspberry Pi Pico module. The Pico can drive the scanning operation, and with an external FTDI USB3.0 device, send four synchronised channels of acquired sample data back to the host computer. Using PCIe connectors and mating edge connectors on the cards, gives a robust and cost effective physical connection. As can be seen from the project page, a lot of mechanical design is complete, and machining has started, so this is a project to keep an eye on in the coming months, and possibly years!

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“This is an answer to a huge demand we’ve had from a number of customers who wanted access to this platform but were limited because of the platform they’re on,” Richard Kerris, Nvidia’s Omniverse VP, said to reporters this week.

Omniverse Cloud is in early access now, and Nvidia is taking applications for it.

Next, Nvidia announced Omniverse OVX, a computing system designed specifically to meet the needs of massive simulations — or industrial digital twins.

Transmutex is reinventing nuclear energy from first principles using a process that uses radioactive waste as a fuel source.

Transmutex, a Swiss company, states on its website that it is “reinventing nuclear energy from first principles” by using a process that uses radioactive waste as a fuel source.

Its transmitter is a particle accelerator that produces nuclear energy with fewer contaminants than any reactor on the market today. The technology represents a valuable tool in the transition to intermittent renewables by providing baseload energy-producing alternatives to fossil-fuel thermal power stations.

The particle accelerator rather than the radioactive fuel creates a controlled nuclear reaction. Turn off the particle beam and the reaction stops immediately. The technology is designed to use a wide range of nuclear fuels including the radioactive waste from existing reactors.

Continue reading “Nuclear Energy Company Proposes a New Reactor to Take Care of the Waste Problem” | >

Devastating residential blazes and wildfires take a terrible toll in terms of deaths and injuries, as well as property loss. Today, researchers will report on a new type of coating that could limit the flammability of wood used in construction, potentially providing more time to escape fires and also curbing their spread. The environmentally friendly flame retardant could also be used for other flammable materials, such as textiles, polyurethane foam and 3D-printed parts.

The researchers will present their results today at the spring meeting of the American Chemical Society (ACS).

Home fires account for the majority of fire deaths and lead to billions of dollars in property damage every year, according to the National Fire Protection Association. Adding fire sprinklers and can help, but another approach is to make construction materials less flammable. That’s the goal of Thomas Kolibaba, Ph.D., who is developing a new for these materials. “This type of treatment, which could be deposited via dipping, spraying or pressure treatment, could make homes much safer,” he says. “The coating could reduce flame spread and smoke production, which could limit damage and give people more time to evacuate.” Unlike most current fire retardant treatments, its ingredients are environmentally benign, and it might also cost less, notes Jaime Grunlan, Ph.D., the project’s principal investigator.

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Biomedical Interventions For Substantial Global Health Concerns — Dr. Emilio Emini, Ph.D., CEO, Bill & Melinda Gates Medical Research Institute

Dr. Emilio A. Emini, Ph.D. is the CEO of the Bill & Melinda Gates Medical Research Institute (https://www.gatesmri.org/), a non-profit organization dedicated to the development and effective use of novel biomedical interventions addressing substantial global health concerns, for which investment incentives are limited, and he leads the Institute’s research and development of novel products and interventions for diseases disproportionately impacting the world’s most vulnerable populations.

Before joining the Gates MRI, Dr. Emini served as director of the HIV and Tuberculosis program at the Bill & Melinda Gates Foundation, where he led the foundation’s efforts focused on accelerating the reduction in the incidence of HIV and TB in high-burden geographies, with the goal of achieving sustained epidemic control.

Continue reading “Dr. Emilio Emini, Ph.D. — CEO — Bill & Melinda Gates Medical Research Institute” | >

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

The anti-cancer molecule salinosporamide A, also called Marizomb, is in Phase III clinical trials to treat glioblastoma, a . Scientists now for the first time understand the -driven process that activates the molecule.

Researchers at UC San Diego’s Scripps Institution of Oceanography found that an enzyme called SalC assembles what the team calls the salinosporamide anti-cancer “warhead.” Scripps graduate student Katherine Bauman is the lead author of a paper that explains the assembly process in the March 21 issue of Nature Chemical Biology.

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It may not feel like it, but our eyes are constantly making rapid, tiny movements called saccades, taking in new information as we focus our gaze on various things in the world. As we do so, our brains receive the input – and depending on what the object of our gaze is, it turns out the brain activity triggered can be quite unique.

“While we typically do not perceive our own eye movements, the abrupt change in visual input with each saccade has substantial consequences at the neuronal level,” researchers explain in a new study led by first author and cognitive neuroscientist Tobias Staudigl from Ludwig Maximilian University of Munich in Germany.

In an experiment, Staudigl and fellow researchers worked with 13 epilepsy patients, who had electrodes implanted in their brains to monitor their condition. This kind of intervention can be helpful for brain scientists, so they often turn to such patients with electrodes already implanted, in case they’d be willing to volunteer their time.

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