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Summary: Seizures originate from an excess of excitatory over inhibitory neural activity in confined regions of the brain, and spread only when they overcome strong inhibitory activity in surrounding regions.

Source: Weill Cornell University.

New evidence from a zebrafish model of epilepsy may help resolve a debate into how seizures originate, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings may also be useful in the discovery and development of future epilepsy drugs.

Analyzing sodium levels in breast cancer tumors can give an accurate indication of how aggressive a cancer is and whether chemotherapy treatments are taking effect, new research has shown.

In a study, by the universities of York and Cambridge and funded by charities Cancer Research UK and Breast Cancer Now, researchers developed a technique using sodium imaging (MRI) to detect salt levels in in mice.

Using this technique, the researchers looked at tumors and discovered that salt (sodium) was being accumulated inside and that more active tumors accumulate more sodium.

BHL Cryotanks have demonstrated a 75% mass reduction compared to existing state-of-the-art aerospace cryotanks (metal or composite), enabling hydrogen aircraft and eVTOL makers to store as much as 10 times more liquid hydrogen fuel without adding mass. As a result, aircraft can travel longer distances without refueling.

GTL has fabricated and tested multiple BHL Cryotanks at a range of scales and has been demonstrated to be leak-tight even after repeated cryo-thermal pressure cycles. This technology has achieved TRL 5+ and is compatible with a variety of cryogenic propellants, including liquid oxygen, liquid methane, and liquid hydrogen.

The BHL Cryotank pictured here measures 2.4 meters long with a 1.2-meter diameter and weighs 12 kilograms (roughly 26 pounds). With the addition of a skirt and vacuum dewar shell, the total system weight is 67 kilograms. This particular tank system can hold over 150 kilograms of liquid hydrogen, giving it a hydrogen storage ratio of at least 50% (the weight of stored hydrogen fuel relative to total system weight), which is as much as 10 times greater than current state-of-the-art fuel tanks. HyPoint estimated that an aircraft equipped with GTL dewar tank technology could achieve as much as four times the range of a conventional aircraft using aviation fuel, cutting aircraft operating costs by an estimated 50% on a dollar-per-passenger-mile basis.