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Realization experiences: a convergent account of insight and mystical experiences

We argue that the powerful transformative effects of mystical-type experiences can be understood using the same machinery that underlies insight problem solving, and that both mystical experiences and insight are species of a genus of “realization experiences”: experiences wherein some phenomenon or piece of information becomes suddenly experienced as real or true. Specifically, we argue that understanding both in this way allows us to model mystical experiences through the same combination of behavioral entropy and graph theory that have successfully been used to model insight problem solving. Starting from tension between novel information and prior representations, the agent destabilizes its representational network to allow it to enter a state of altered salience and enhanced associations to update the network.

The Next Chip Breakthrough Is Not a Machine

Go to https://sintra.ai/intech or use code INTECH to get an exclusive 72% off all plans. 14-day money-back guarantee.

Timestamps:
00:00 — The Limits of Light
07:44 — The Chemistry Hack. How It Works.

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Let’s connect on LinkedIn: / anastasiintech
Instagram: / anastasi.in.tech
Patreon: / anastasiintech.

Scientists discover how to freeze transplant organs without cracking them

Scientists are making a major leap toward freezing organs for future use without damaging them. A new study reveals that one of the biggest obstacles—cracking during ultra-cold preservation—can be reduced by carefully tuning the temperature at which tissues enter a glass-like state. This breakthrough builds on recent successes in cryopreserved organ transplants and could bring the long-imagined idea of “banking” organs for later use much closer to reality.

Bacterial defense system builds DNA in unexpected new way to stop viruses

Scientists at Stanford University have discovered that DRT3, a unique defense system found in bacteria, creates DNA to protect against viral infections. DRT3 is made up of two different enzymes called reverse transcriptases, Drt3a and Drt3b, and a piece of noncoding RNA (ncRNA). Together, this trio makes long, double-stranded DNA consisting of alternating repeats (GT/AC).

A physicist reveals how time travel is possible | Jim Al-Khalili

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Time is the one thing every human being experiences identically, or so we assume.

Physicist Jim Al-Khalili dismantles that assumption, explaining how velocity and gravity don’t just affect clocks but actually alter the rate at which time passes for the person experiencing it.

Preorder Jim Al-Khalili’s forthcoming book, On Time: The Physics That Makes the Universe, here: https://www.amazon.com/Time-Physics-T?tag=lifeboatfound-20

About Jim Al-Khalili: Jim is a multiple award-winning science communicator renowned for his public engagement around the world through writing and broadcasting and a leading academic making fundamental contributions to theoretical physics, particularly in nuclear reaction theory, quantum effects in biology, open quantum systems and the foundations of quantum mechanics. Jim is a theoretical physicist at the University of Surrey where he holds a Distinguished Chair in physics as well as a university chair in the public engagement in science. He received his PhD in nuclear reaction theory in 1989 and has published widely in the field. His current interest is in open quantum systems and the application of quantum mechanics in biology.

About Jim Al-Khalili:

The Why Is a Discipline: Goodhart’s Law and AI

A reader asked me a question this week that I have been thinking about ever since.

She did not ask whether AI could malfunction. She did not ask whether bad actors could misuse it. She asked something sharper:

Can a system produce bad outcomes systematically, even when intent is good, and nothing is broken?

The answer is yes. And it is the most dangerous category of bad outcome, because nobody is at fault and nothing is broken.

We have all the evidence we need. Amazon ran into it. YouTube ran into it. Hospitals are running into it now. AI labs are about to run into it at a planetary scale. And almost nobody is talking about why.

A 1975 economic principle explains it cleanly. A reader’s question forced me to refine an argument I have been making for years.

New essay: [ https://www.singularityweblog.com/goodharts-law-ai/](https://www.singularityweblog.com/goodharts-law-ai/)

Detecting multiple cancers and other diseases from a single blood sample

UCLA scientists have developed a simple and cost-effective blood test that, in early studies, shows promise in detecting multiple cancers, various liver conditions and organ abnormalities simultaneously by analyzing DNA fragments circulating in the bloodstream. The test, described in the journal Proceedings of the National Academy of Sciences, could offer a powerful and more affordable approach to early disease detection and comprehensive health monitoring.

“Early detection is crucial,” said Dr. Jasmine Zhou, the study’s senior author, a professor of pathology and laboratory medicine and investigator at the UCLA Health Jonsson Comprehensive Cancer Center. “Survival rates are far higher when cancers are caught before they spread. If you detect cancer at stage one, outcomes are dramatically better than at stage four.”

How the MethylScan blood test works The new method, called MethylScan, works by analyzing cell-free DNA (cfDNA), tiny fragments of genetic material released into the blood when cells die. Because cells from every organ shed DNA into the bloodstream, cfDNA carries molecular signals that reflect what is happening throughout the body.

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