Lifeboat Foundation

Aging is a highly complex process with thousands of genes influencing our health, which poses a challenge for researchers looking to explain and target the underlying processes that lead to declining health. Researchers from the Babraham Institute’s Epigenetics research program have published a map of genetic interactions in C. elegans in iScience which can be used to identify new genes that influence lifespan and that have equivalent genes in humans.

Researchers use simple model organisms like the nematode worm C. elegans to gather information that can inform studies on human aging because many genes are shared or have counterparts in other species. However, there are some conceptual and technical challenges that apply to the study of aging in model organisms. Dr. Casanueva, Group leader in the Epigenetics research program explains: “The way researchers usually study gene function is by disrupting its function and observing what happens. The disruption of some genes causes worms to live a very long-life. In this way, researchers have found the so-called ‘longevity-pathways.” However, the complexity underlying aging means that it is not enough to focus on individual genes. We need to study the overall organization of longevity by generating a systems-wide view.”

In collaboration with the physicist Marta Sales Pardo at University of Rovira i Virgili, Dr. Casanueva and her lab set out to cast a wider net when it comes to studying longevity genes. Together they created the largest network of gene regulatory interactions that are found in a long-lived type of C. elegans. In this network, the relationships between genes are represented by lines, and represented in different layers based on the flow of information between genes. The middle of the web represents the genes with the most influence, in this case, they receive complex input signals and de-code them, and connect to an output layer of genes. The researchers found that most key genes for longevity belong to transcription factors and metabolic genes.

Occasionally, there are things that Google Maps can’t find but a B-2 stealth bomber is not among them, according to a Redditor.

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Several strategies are being explored to halt or reverse the effects of aging.

A box full of $50 and $100 bills, totaling $180,000, was sent to the physics department at City College of New York. An enclosed note from the mysterious donor asked the school to use the cash to fund scholarships for needy students.

When a City College physics professor opened an ordinary box that had been sitting in the mailroom, he was startled by its contents.

Continue reading “A Box of Cash, a Secret Donor and a Big Lift for Some N.Y.C. Students” »

A single treatment with room temperature plasma could accelerate repair of large bone defects.

So the bristle worm jaw is both metal-like and yet not. As Zelaya-Lainez puts it, “Here we are dealing with a completely different material, but interestingly, the metal atoms still provide strength and deformability there, just like in a piece of metal.”

Observing the creation of a metal-like material from biological processes is a bit of a surprise and may suggest new approaches to materials development. “Biology could serve as inspiration here,” says Hellmich, “for completely new kinds of materials. Perhaps it is even possible to produce high-performance materials in a biological way — much more efficiently and environmentally friendly than we manage today.”

Scientists have used state-of-the-art 3D printing and microscopy to provide a new glimpse of what happens when taking magnets to three-dimensions on the nanoscale—1000 times smaller than a human hair.

The international team led by Cambridge University’s Cavendish Laboratory used an advanced 3D printing technique they developed to create magnetic double helices—like the double helix of DNA—which twist around one another, combining curvature, chirality, and strong magnetic field interactions between the helices. Doing so, the scientists discovered that these magnetic double helices produce nanoscale topological textures in the magnetic field, something that had never been seen before, opening the door to the next generation of magnetic devices. The results are published in Nature Nanotechnology.

Magnetic devices impact many different parts of our societies, magnets are used for the generation of energy, for data storage and computing. But magnetic computing devices are fast approaching their shrinking limit in two-dimensional systems. For the next generation of computing, there is growing interest in moving to three dimensions, where not only can higher densities be achieved with 3D nanowire architectures, but three-dimensional geometries can change the magnetic properties and offer new functionalities.

While AI can provide real-time analysis of enormous amounts of data, an AI system coupled with blockchain technology can provide a transparent data governance model for quicker validation amongst various stakeholders through smart contracts and DAOs.

Blockchain benefits can address AI’s shortcomings

Applying the benefits of blockchain technology can help address various shortcomings of AI and help in increasing people’s trust in AI-based applications. With Blockchain, AI applications acquire the qualities of decentralization, distributed data governance, data immutability, transparency, security, and real-time accountability. Many AI-enabled intelligent systems are criticized for their lack of security and trust levels. Blockchain technology can essentially help in addressing the security and trust deficit issues to a significant extent. Enormous challenges remain for both blockchain technology and Artificial Intelligence. Still, when combined, they display tremendous potential and will complement each other to restore the trust factor and improve efficiency at large.

NASA and the Russian space agency Roscosmos are finalizing an agreement to launch the first cosmonaut on a SpaceX Crew Dragon spacecraft, agency officials confirmed on Monday (Dec. 20).