Is pancreatic cancer hereditary? Are there any genetic mutations associated with it? Our pancreatic cancer expert Florencia McAllister, M.D., weighs in on these questions and seven more.
How to Help a Loved One
Posted in neuroscience
Identifying how to help a loved one struggling with mental health challenges can feel overwhelming. Our helpful guide is filled with tips, strategies, and resources that can accelerate the journey to recovery.
In a study from Yale-NUS College, researchers found evidence that metabolic dysfunction is a primary cause of Alzheimer’s disease is the most common neurodegenerative disease affecting the elderly worldwide, as well as one of the most common causes of dementia. In Singapore, one in 10 people aged 60 or above is believed to suffer from dementia.
Researchers at Harvard University are investigating whether human genes could reverse the effects of aging. NBC Medical Fellow Dr. Akshay Syal got exclusive access to their lab to discuss the future of how to defy aging.
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No questions concerning plasma dilution or E5, but a good interview with chapters.
Professor Matt Kaeberlein discusses the Dog Aging Project, longevity, Rapamycin, mTOR, and if we can ‘solve aging’
Timestamps:
0:00 Dog Aging Project.
4:18 Intermittent fasting.
10:23 Best longevity lifestyle.
16:25 Rapamycin & mTOR
23:27 Rapamycin human study.
30:18 Protein restriction diets.
39:46 Combination longevity therapies.
45:38 SGLT2i therapies.
47:23 Metformin & longevity.
52:50 Navigating misinformation.
55:28 Creatine.
59:00 Best exercises for longevity.
01:03:00 Can we solve aging?
01:09:45 Epigenetic reprogramming.
1:16:50 Supplements Dr Kaeberlein takes.
Donate towards our Rapamycin & Exercise clinical study: https://bit.ly/3QwugRx.
My full supplement stack: https://drstanfield.com/my-supplements/
The Israeli government has teamed up with a defense contractor to invent a new material matrix that can hide soldiers from infrared sensors, making them more difficult to detect.
Polaris Defense’s Kit 300 system is a “thermal visual concealment” system that uses a combination of “metals, microfibres, and polymers” to mask a soldier’s thermal signature, according to Business Insider.
Thermal imaging technology creates a visual representation of an object via the invisible infrared (“heat radiation”) the object emits. If that object radiates heat, a thermal imager will show an image of it, with different colors representing relative levels of heat.
Our bodies harbor countless microbes—and so do our tumors, it turns out. Over the past 5 years, researchers have shown cancer tissue contains entire communities of bacteria and fungi. Now, it appears some of the bacteria may be cancer’s accomplices. In a paper in this week, a team led by Susan Bullman of the Fred Hutchinson Cancer Center reports that in oral and colorectal tumors, bacteria live inside cancer cells and boost their production of proteins known to suppress immune responses. The microbial interlopers may set off a chain reaction that prevents the immune system from killing cancerous cells, and they may also help cancer metastasize to other parts of the body.
The study doesn’t entirely clinch the case for a bacterial role in cancer, but it is very suggestive, says Laurence Zitvogel, a tumor immunologist at the Gustave Roussy Institute. “It shows that bacteria in colorectal and oral tumors can actively disturb the immune equilibrium,” she says.
Confirmation that microbes can cause tumors to grow or spread could open up new ways to make cancer treatment more effective, for instance by killing bacteria with antibiotics. And because each type of cancer appears to come with a unique microbiome, researchers are exploring whether microbes could be used as a diagnostic tool to detect cancer early in a blood sample.
Just as car created job for drivers, computer created job for data entry operator.robots will also create new types of high paying jobs.
For decades, the arrival of robots in the workplace has been a source of public anxiety over fears that they will replace workers and create unemployment.
Now that more sophisticated and humanoid robots are actually emerging, the picture is changing, with some seeing robots as promising teammates rather than unwelcome competitors.
‘Cobot’ colleagues
Take Italian industrial-automation company Comau. It has developed a robot that can collaborate with – and enhance the safety of – workers in strict cleanroom settings in the pharmaceutical, cosmetics, electronics, food and beverage industries. The innovation is known as a “collaborative robot”, or “cobot”.
Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small set of patients with the autoimmune disease lupus. Penn Medicine CAR T pioneer Carl June, MD, and Daniel Baker, a doctoral student in Cell and Molecular Biology in the Perelman School of Medicine at the University of Pennsylvania, discuss this development in a commentary published today in Cell.
“We’ve always known that in principle, CAR T therapies could have broad applications, and it’s very encouraging to see early evidence that this promise is now being realized,” said June, who is the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine at Penn Medicine and director of the Center for Cellular Immunotherapies at Penn’s Abramson Cancer Center.
T cells are among the immune system’s most powerful weapons. They can bind to, and kill, other cells they recognize as valid targets, including virus-infected cells. CAR T cells are T cells that have been redirected, through genetic engineering, to efficiently kill specifically defined cell types.
Vitaly Vanchurin, physicist and cosmologist at the University of Minnesota Duluth speaks to Luis Razo Bravo of EISM about the world as a neural network, machine learning, theories of everything, interpretations of quantum mechanics and long-term human survival.
Timestamp of the conversation:
00:00 — Opening quote by Vanchurin.
00:53 — Introduction to Vanchurin.
03:17 — Vanchurin’s thoughts about human extinction.
05:56 — Brief background on Vanchurin’s research interests.
10:24 — How Vanchurin became interested in neural networks.
12:31 — How quantum mechanics can be used to understand neural networks.
18:56 — How and where does gravity fit into Vanchurin’s model?
20:39 — Does Vanchurin incorporate holography (AdS/CFT) into hid model?
24:14 — Maybe the entirety of physics is an “emergent” neural network.
28:08 — Maybe there are forms of life that are more fit to survive than humans.
28:58 — Maldacena’s “principle of Maximal life“
29:28 — Theories of Everything.
31:06 — Why Vanchurin’s framework is potentially a true TOE (politics, ethics, etc.)
34:07 — Why physicists don’t like to talk to philosophers and ask big questions.
36:45 — Why the growing number of theories of everything?
39:11 — Apart from his own, does Vanchurin have a favorite TOE?
41:26 — Bohmian mechanics and Aharanov’s Two-time approach to quantum mechanics.
43:53 — How has Vanchurin’s recent paper been received? Beliefs about peer review.
46:03 — Connecting Vanchurin’s work to machine learning and recommendations.
49:21 — Leonard Susskind, quantum information theory, and complexity.
51:23 — Maybe various proposals are looking at the same thing from different angles.
52:17 — How to follow Vanchurin’s work and connect to him.
Vanchurin’s paper on the world as a NN: https://arxiv.org/abs/2008.01540
Vanchurin on a theory of machine learning: https://arxiv.org/abs/2004.
Vanchurin’s website and research interests: https://www.d.umn.edu/cosmology/
Learn more about EISM at www.eism.eu.